A5070666153- Respiratory viral infections research
- Antimicrobial Resistance in Staphylococcus
- Pneumonia and Respiratory Infections
- Bacterial Identification and Susceptibility Testing
- Pediatric health and respiratory diseases
- Bacterial biofilms and quorum sensing
- Congenital Diaphragmatic Hernia Studies
- Antifungal resistance and susceptibility
- Antibiotic Resistance in Bacteria
- Tracheal and airway disorders
- Viral Infections and Vectors
- Clostridium difficile and Clostridium perfringens research
- Sodium Intake and Health
- Surgical site infection prevention
- Burkholderia infections and melioidosis
- Veterinary medicine and infectious diseases
- Chronic Kidney Disease and Diabetes
- Toxoplasma gondii Research Studies
- Reproductive tract infections research
- Infections and bacterial resistance
- Bacterial Infections and Vaccines
- Urinary Tract Infections Management
- Venomous Animal Envenomation and Studies
- Vasculitis and related conditions
- Bone fractures and treatments
Rajarata University of Sri Lanka
2015-2024
Ministry of Health and Sanitation
2021
University of Peradeniya
2021
Teaching Hospital Kandy
2017-2020
Yahoo (United Kingdom)
2015
Chronic kidney disease (CKD) of unknown etiology (CKDu) is a serious health issue in Sri Lanka. One-to-one age and sex-matched two sample comparative study was carried out the Medawachchiya divisional secretariat area North Central Province (NCP) Lanka, by randomly selecting 100 CKDu patients subjects from non-CKDu affected families same area. An interviewer-administered questionnaire used for collection data pertaining to occupation, medical history lifestyle. Data were analyzed using...
Respiratory syncytial virus (RSV) is a leading cause of pediatric death, with >99% mortality occurring in low- and lower middle-income countries. At least half RSV-related deaths are estimated to occur the community, but clinical characteristics this group children remain poorly characterized.The RSV Global Online Mortality Database (RSV GOLD), global registry under-5 who have died illness, describes dying through data sharing. GOLD acts as collaborative platform for deaths, including...
Introduction The animal husbandry comes to play an important role according new economic reforms of the rural economy in South Asia including Sri Lanka, and farming community has a poor knowledge about hygienic issues husbandry, which can lead spread pathogenic bacterial strains from animals humans.Our study was conducted evaluate methicillin susceptible Staphylococcus aureus (MRSA) colonization its antimicrobial resistance pattern among livestock (n=188) related farmers (n=94) Anuradhapura...
Chronic Kidney disease of uncertain etiology (CKDu) has become a significant burden, affecting farming community Sri Lanka and the exact etiology, which could be multifactorial, is not hitherto established. This study aimed to determine association past hantavirus infection leptospirosis with occurrence CKDu. A cohort ( n = 179) known CKDu patients living in high-CKDu prevalent areas Anuradhapura district was compared group 49 healthy, sex-matched younger blood relatives (control-1) another...
Candidemia is an emerging hospital-acquired bloodstream infection (BSI). It common among severely ill and immunocompromised patients. Even following appropriate therapy in candidemia, recent studies reveal relative high mortality (40%). The global incidence of candidemia shows incline. In Sri Lanka, candida speciation often difficult where basic facilities are less available. We have compared the risk factors, epidemiology, demography, performance HiChrome Candida differential agar (HiCA)...
The prevalence of hMPV infections in Sri Lanka has not been reported and here we report a case series infection children less than 5 years. Patients with ARTI were included from Teaching Hospital, Anuradhapura March 2013 to August 2014. Indirect fluorescence assay was performed on nasopharyngeal aspirates for the identification respiratory viruses [respiratory syncytial virus (RSV), parainfluenza 1, 2 3, influenza A B hMPV]. Moreover, reverse transcriptase-polymerase chain reaction done...
Aim: Worldwide, an estimated 2 billion healthy people carry Staphylococcus aureus (SA) and of these, up to 53 million are thought methicillin-resistant SA (MRSA).MRSA bacteremia patients more critical manage timely introduction antibiotics is life-saving.The aim the study was elucidate prevalence MRSA in different units Teaching Hospital, Anuradhapura (THA), Sri Lanka assess clinical characteristics associated mortality related vancomycin therapy. Materials Methods:The data on which were...
Background: Acute respiratory tract infection (ARTI) is one of the most common acute illnesses childhood. Mostly encountered viral etiology ARTI in children under 5 years are syncytial virus (RSV), parainfluenza types 1, 2 and 3 (PIV), adenovirus (AV), influenza A B, coronavirus (CoV), human Boca (hBoV) metapeumo virus. (hMPV) This study was conducted to identify burden hospitalized with ARTIs map occurrence these viruses local seasonality. Methods & Materials: Nasopharyngeal aspirates (NPA)...
The present study was done to identify the viral diversity, seasonality and burden associated with childhood acute respiratory tract infection (ARTI) in Sri Lanka. Nasopharyngeal aspirates (NPA) of hospitalized children (1 month—5 years) ARTI were collected 2 centers (wet dry zones) from March 2013 August 2014. Respiratory antigen detection by immunofluorescence assay (IFA) used infecting viruses. IFA negative 100 NPA samples tested for human metapeumovirus (hMPV), bocavirus corona viruses...
Medical students who engage in clinical learning healthcare settings can be potential methicillin-resistant Staphylococcus aureus (MRSA) carriers.This is a descriptive cross-sectional study having follow-up approach. Three batches of medical were studying at the Faculty Medicine and Allied Sciences, Rajarata University Sri Lanka (1st, 3rd 5th years MBBS course) screened for nasal axillary MRSA colonization. The first-year before 6 months after learning. knowledge about infection control was...
We have assessed the risk factors for occurrence of hospital-acquired (HA) and community-acquired (CA) viral acute respiratory tract infections (ARTIs) in children. Children (1-60 months) who were having ARTI on admission develops following 48 h after or 3 days discharge included. Indirect immunofluorescence assay (IFA) was performed multivariable analyses done to determine development CA HA-ARTI.Total 818 with ARTIs, 226 (27.6%) RSV cases detected. Out 226, 86 (38.0%) HA-RSV CA-viral-ARTI...
Alkaptonuria is a rare disorder that results from an inherited deficiency of aromatic amino acid metabolism. Only 21% the children under age 1 year having disease are identified in clinics. We report case 1-week-old child first-degree consanguineous couple with symptom frequent nappy staining. Analysis urine showed homogentisic concentration exceeding 200 mg/dL. The physical examination revealed was healthy. parents’ watchfulness and close attention paid to were keys early detection this...
Sri Lanka comprises of a well-established traditional orthopedic treatment system. A 14 year old child had compound fracture over shaft humerus. The internal fixator Kirschner (k) wire was applied following allopathic and after three weeks, it removed as there no healing wound site. Patient asked to follow clinic but defaulted presented Ayurveda management. X-ray reports showed nonunion the Initially, bone immobilized for six months using bamboo splints. Prior applying splints, during every...
Bacteremia following Staphylococcus aureus is a serious clinical condition which often associated with distant metastatic infections. One of the most dreaded complications bacteremia infective endocarditis. Cloxacillin common antibiotic prescribed for suspected staphylococcal infections and confirmed methicillin-sensitive Prolonged use cloxacillin may lead to neutropenia. A 38-year-old Sinhalese man presented Teaching Hospital Kurunegala, Sri Lanka, complaining 3-week history fever; he was...
Methicillin-resistant
is a Gram-positive coccobacillus, and member of the normal human microbiota.
Abstract Objectives Military personnel, because of the unique nature their duties, are reluctant to face stressors. Living in hot and humid conditions they frequently suffer dehydration. Army soldiers living dry zone Sri Lanka, were screened for chronic kidney disease (CKD), common non-communicable diseases methicillin resistant Staphylococcus aureus (MRSA) colonization. Albumin creatinine ratio > 30 mg/g urine taken as cut-off detection CKD. Results Screened 417 soldiers, all men body...
Surgeons instruct the patients to avoid postoperative bathing and dress wounds until sutures are removed. All were sutured at end of surgery kept undressed. Participants received a tap water body bath where covered wound after 24h surgery. The control group asked not wet dressed surgical site inspection on days 3 5. followed up in clinic 14 30 surgery, when age, sex type surgery-matched controls' infection was significantly high clean/contaminated contaminated appendicectomy, breast lump...
Burkholderia pseudomallei is the bacterium that causes melioidosis. It mostly a tropical disease, and particularly common in Southeast Asia northern Australia. The intensive intravenous phase oral prolonged eradication are two phases of melioidosis treatment. current recommended treatment for co-trimoxazole (TMP/SMX).Two patients were diagnosed with B. bacteremia without focus treated TMP/SMX folic acid during phase. Both presented neutropenic sepsis pneumonia pyelonephritis at days 48 45...