- Respiratory Support and Mechanisms
- Airway Management and Intubation Techniques
- Cardiac Arrest and Resuscitation
- Intensive Care Unit Cognitive Disorders
- Neonatal Respiratory Health Research
- Pneumonia and Respiratory Infections
- Maternal and Neonatal Healthcare
- Pleural and Pulmonary Diseases
- Respiratory viral infections research
- Infant Development and Preterm Care
- Mosquito-borne diseases and control
- Parasites and Host Interactions
- Lysosomal Storage Disorders Research
- Myofascial pain diagnosis and treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Viral Infections and Outbreaks Research
- Diagnosis and treatment of tuberculosis
- Virology and Viral Diseases
- Public Health and Social Inequalities
- Amoebic Infections and Treatments
- Interpreting and Communication in Healthcare
- Child Nutrition and Feeding Issues
- Indigenous Health and Education
- Obesity, Physical Activity, Diet
- Chronic Obstructive Pulmonary Disease (COPD) Research
Instituto de Medicina Integral Professor Fernando Figueira
2008-2024
Hospital de Clínicas "José de San Martín"
2021
Respiratory syncytial virus (RSV) is a leading cause of pediatric death, with >99% mortality occurring in low- and lower middle-income countries. At least half RSV-related deaths are estimated to occur the community, but clinical characteristics this group children remain poorly characterized.The RSV Global Online Mortality Database (RSV GOLD), global registry under-5 who have died illness, describes dying through data sharing. GOLD acts as collaborative platform for deaths, including...
The clinical-related input and processing of intestinal afferents to the spinal cord is not well known. This study aims develop an electrophysiological experimental animal model from colon during conditions such as hyperexcitability or ischemia. Spinal evoked potentials (SCEP) were elicited by colonic stimulation in ten male adult Sprague-Dawley rats anesthetized with thiobarbital, 60 mg kg-1 i.p. After laminectomy (T11 L5), a tungsten electrode (500 μm; <50Ω) was placed dorsum record...
Abstract Introduction: the infection of chikungunya virus presents clinical manifestations variables, particularly in infants which may present multiple cutaneous manifestations. Description: a case series study was carried out an analytical character 14 (>28 days to < 2 years old) admitted hospital between November 2015 and January 2016 with suspected chikungunya, by specific IgM reactive serology. Patients positive for dengue fever, Zika virus, bacterial infections other exanthematic...
This study sought to translate the Cornell Assessment of Pediatric Delirium from English into Brazilian Portuguese and cross-culturally adapt it for use in Brazil.Following authorization granted by its main author, processes translation cross-cultural adaptation were performed with regard accordance following internationally recommended steps: original two native speakers target language; synthesis translated versions; back-translation review harmonization back-translation; a version an...
Abstract Objectives: to assess the functional independence, capacity and respiratory muscle strength (RMS) in individuals with mucopolysaccharidosis (MPS) type VI. Methods: this cross-sectional study, Pediatric Evaluation of Disability Inventory (PEDI) Functional Independence Measure (FIM) scales were used independence. The RMS assessed by a 6-minute walk test (6MWT) Manovacuometry, respectively. associations between 6MWD analyzed using adjusted simple linear regression models. And besides,...
To describe the use of noninvasive ventilation to prevent tracheal intubation in children a pediatric intensive care unit and analyze factors related respiratory failure.A retrospective cohort study was performed from January 2016 May 2018. The population included aged 1 14 years who were subjected as first therapeutic choice for acute failure. Biological, clinical managerial data analyzed by applying model with variables that obtained significance ≤ 0.20 bivariate analysis. Logistic...
As the diagnosis of Pediatric venous thromboembolism has dramatically increased in recent decades, this study aims to evaluate these patients, determining incidence and describing their biological clinical characteristics.
Objetivo: Avaliar o conhecimento da equipe de enfermagem acerca das medidas cuidados para Pneumonia Associada a Ventilação Mecânica (PAVM) na unidade terapia intensiva (UTI). Métodos: Estudo descritivo, do tipo corte transversal. A amostra foi composta por 318 participantes (95 enfermeiros e 225 técnicos enfermagem). Resultados: frequência com desempenho adequado no questionário 87% 51,5%. dos que responderam à questão “você sente possui suficiente prevenção PAVM?” 52,6% 24% respectivamente....
Meningite é a inflamação das meninges, causada principalmente por bactérias e vírus, além de fungos agentes não infecciosos. O presente trabalho teve como objetivo descrever meningite bacteriana viral aguda, abordando o quadro clínico, epidemiologia, diagnóstico mecanismos patogênicos. Trata-se uma revisão da literatura, desenvolvida entre fevereiro 2022 2023 utilizando base dados Scientific Eletronic Library OnLine (SciELO), Literatura Latino-Americana do Caribe em Ciências Saúde (Lilacs),...
Resumo Introdução: amiotrofia espinhal do tipo 1 (AME 1) é uma doença genética autossômica recessiva que promove morte celular de neurônios motores localizados no corno anterior da medula e núcleos tronco cerebral. A precoce morbimortalidade está associada à disfunção bulbar insuficiência respiratória, necessitando internamento hospitalar suporte ventilatório artificial. O objetivo estudo foi divulgar a relevância manutenção paciente com AME sem prótese ventilatória invasiva protocolo...
Serum levels of sCD40L, sCD40 and sCD62P were evaluated in sickle cell anemia (SCA) patients aged between 2 16 years with normal transcranial Doppler (TCD) no stroke (G1, n = 24); SCA abnormal TCD (G2, 16); a previous history (G3, 8), and; healthy controls (aged to 13 years; 26). The sCD40L significantly higher the G1, G2 G3 groups, compared (p 0.0001, p < 0.0002 0.004, respectively). Among SCA, found group, group 0.03). In analysis, high G3, G1 0.0001), 0.03) G4 0.01), also had levels,...
To translate and cross-culturally adapt the Cornell Assessment of Pediatric Delirium anchor points from English to Brazilian Portuguese.For translation cross-cultural adaptation points, all steps recommended internationally were followed after authorization for use by lead author. The stages as follows: original version into Portuguese two bilingual translators who native speakers target language, synthesis versions, reverse source review back-translation, a committee experts preparation...
Objectives. To perform a temporal validation of predictive model for death in children with visceral leishmaniasis (VL). Methods. A children-exclusive due to VL (Sampaio et al. 2010 model), using retrospective cohort, hereby called cohort. The cohort convenience sample was made 156 patients less than 15 years old hospitalized between 2008 and 2018 VL. Patients included the Sampaio study are here denominated derivation which composed 546 same hospital setting period from 1996 2006....
Abstract Background The imbalance of the Renin Angiotensin System in favor angiotensin II has been described Covid-19-patients. regulates life processes, such as cell growth and division can promote apoptosis initiating an inflammatory process with release proinflammatory cytokines. receptor blockers (ARBs) block AT1 could have a beneficial effect reducing Covid-19 inflammation. Purpose To assess whether Telmisartan is effective C-reactive protein (CRP) plasma levels hospitalized patients...
In a case series of 152 children aged from 2 to 132 months will pleural emphema paediatric tertiary hospital in Luanda, Angola between September 2004 and March 2005, the authors found high prevalence anaemia malnutrition. The most prevalent bacteria fluid were: D pneumoniae, Haemophyllus S aureus. median for stay was 25 days. lethality 7.8% not statistically associated with malnutrition, although this variable associated, multivariate analysis, prolonged hospitalization time.
<b>Background:</b> The beneficial effects of assisted mechanical ventilation have been put on hold, mainly because recent evidences showing that spontaneous breathing may exacerbate lung injury by large changes in transpulmonary pressure severe acute respiratory distress syndrome (ARDS). However, so far, no study has evaluated the with different levels PEEP ventilator-induced (VILI) mild ARDS, which is main clinical indication for breathing. <b>Aim:</b> To compare pressure-support (PSV) and...
<b>Introduction:</b> Maroteaux-Lamy Syndrome (MPS VI) is a rare type of mucopolysaccharidosis in the world, however Brazil it one most commonly diagnosed. <b>Objectives:</b> to measure functionality, functional capacity and strength respiratory muscles MPS VI carriers Brazilian Center inborn errors metabolism. <b>Method:</b> cross sectional study. Pediatric Evaluation Disability Inventory (PEDI) or Functional Independence Measure (FIM) was applied according with age. Relation between total...
<b>Background:</b> prolonged mechanical ventilation (MV) is synonymous with failure in ventilatory weaning. To identify the risk factors related MV children undergoing cardiac surgery (CS) may contribute for early intervention and a better prognosis. <b>Objective:</b> to associated CS northeastern Brazil. <b>Method:</b> retrospective study of childrenunder postoperative period large hospital located Brazil during 2012. Children immunodeficiency, cystic fibrosis, severe neurological disease...
Objetivo: Traduzir e adaptar transculturalmente o instrumento Nurses’ knowledge of port-a-cath maintenance ao português falado no Brasil. Métodos: Estudo qualitativo de tradução adaptação transcultural, realizado em um hospital escola do Nordeste Embasado nas recomendações internacionais iniciado após autorização pela autora instrumento, adotou as seguintes etapas: original por dois tradutores bilíngues nativos português; reversa inglês; síntese das traduções outro tradutor; revisão comitê...
OBJECTIVE: To translate and cross-culturally adapt the Cornell Assessment of Pediatric Delirium anchor points from English to Brazilian Portuguese. METHODS: For translation cross-cultural adaptation points, all steps recommended internationally were followed after authorization for use by lead author. The stages as follows: original version into Portuguese two bilingual translators who native speakers target language, synthesis versions, reverse source review back-translation, a committee...