A5024665361- Parallel Computing and Optimization Techniques
- Force Microscopy Techniques and Applications
- Neuroinflammation and Neurodegeneration Mechanisms
- Advanced Data Storage Technologies
- Advanced Memory and Neural Computing
- Immune cells in cancer
- Embedded Systems Design Techniques
- CCD and CMOS Imaging Sensors
- Robotics and Automated Systems
- Molecular Biology Techniques and Applications
- Fluid Dynamics and Mixing
- Boron and Carbon Nanomaterials Research
- Spectroscopy Techniques in Biomedical and Chemical Research
- Single-cell and spatial transcriptomics
- Diamond and Carbon-based Materials Research
- High-Velocity Impact and Material Behavior
- Heat Transfer and Boiling Studies
- High-pressure geophysics and materials
- Carbon Nanotubes in Composites
- Ferroelectric and Negative Capacitance Devices
- Atherosclerosis and Cardiovascular Diseases
- Glioma Diagnosis and Treatment
- Transcranial Magnetic Stimulation Studies
- Graphene research and applications
- Advanced X-ray Imaging Techniques
Tongren Hospital
2025
Shanghai Jiao Tong University
2024-2025
Imperial College London
2024
Tsinghua University
2001-2024
XinHua Hospital
2024
University of Shanghai for Science and Technology
2023
Changhai Hospital
2022-2023
Second Military Medical University
2022-2023
Wuhan University
2022
Subclassification of tumors based on molecular features may facilitate therapeutic choice and increase the response rate cancer patients. However, highly complex cell origin involved in osteosarcoma (OS) limits utility traditional bulk RNA sequencing for OS subclassification. Single-cell (scRNA-seq) holds great promise identifying heterogeneity. this technique has rarely been used study tumor By analyzing scRNA-seq data six conventional nine cancellous bone (CB) samples, we identified 29...
The classification of microglial M1/M2 polarization in the acute phase ischemic stroke remains controversial, which has limited further advances neuroprotective strategy. To thoroughly assess phenotypes, we made middle cerebral artery occlusion model mice to simulate pathological processes from normal conditions ischemia and then early reperfusion period. temporal changes gene profiles, cell subtypes, function were comprehensively analyzed using single-cell RNA sequencing. We identified...
Abstract Structural superlubricity (SSL) is a state of contact with no wear and ultralow friction. SSL has been characterized at van der Waals (vdW) layered materials, while its stability under extreme loading conditions not assessed. By designing both self-mated non-self-mated vdW contacts materials chosen for their high strengths, we report outstanding robustness very pressures in experiments. The incommensurate between graphite interfaces can maintain the pressure lower than 9.45 GPa,...
Astrocyte plays important roles in the pathogenesis of ischemic stroke and reperfusion injury. They intensively participate energy metabolism brain, while their heterogeneity function after remain controversial. By employing single-cell sequencing mice cortex at 12 h transient middle cerebral artery occlusion (tMCAO) comparing with similar published datasets 24h tMCAO, we uncover cellular phenotypes dynamic change astrocytes acute phase stroke. In this study, separately identified 3 major...
Coherent modulation imaging (CMI) is a lessness diffraction technique, which uses an iterative algorithm to reconstruct complex field from single intensity pattern. Deep learning as powerful optimization method can be used solve highly ill-conditioned problems, including phase retrieval. In this study, physics-driven neural network for CMI developed, termed CMINet, the complex-valued object The developed approach optimizes network's weights by customized physical-model-based loss function,...
Interlayer shear between graphene sheets plays an important role in graphene-based materials and devices, but the effect of in-plane deformation graphene, which may depend on size, has not been fully understood. In this paper, size interlayer behavior two is studied based a non-linear shear-lag model with energy barrier analysis, both lattice registry elastic are taken into account, molecular dynamics (MD) simulations carried out to verify model. Both theoretical prediction MD show that...
The latest 2021 WHO classification redefines glioblastoma (GBM) as the hierarchical reporting standard by eliminating glioblastoma, IDH-mutant and only retaining tumor entity of “glioblastoma, IDH-wild type.” Knowing that subclassification tumors based on molecular features is supposed to facilitate therapeutic choice increase response rate in cancer patients, it necessary carry out newly defined GBM. Although differentiation trajectory inference single-cell sequencing (scRNA-seq) data holds...
This paper aims to develop a distributed channel estimation (CE) algorithm for spatially non-stationary (SNS) channels in extremely large aperture array systems, addressing the issues of high communication cost and computational complexity associated with traditional centralized algorithms. However, SNS differ from conventional stationary channels, presenting new challenges such as varying sparsity patterns different antennas. To overcome these challenges, we propose novel CE accompanied by...
DNN inference of edge devices has been very important for a long time with large computing and energy consumption demand. This paper proposes TPE(Transformation Process Element) three characteristics. Firstly, TPE method Data Segmentation Skip Pre-Reorganization(DSSPR). Secondly, Typical Value Matching Calibration Computer (TVMCC) system, which converts direct calculation into matching calibration calculation. Thirdly, includes Format Pre-Configuration Self-Adjustment (DFPCSA) scheme....
Recently, the edge-device DNN training has become of high importance, while computation and access energy consumption are too large. This paper proposes a CPE (Compress Process Element) with three characteristics. Firstly, method Reordering Reusing Data (RRD) by controlling output to reorder data. Secondly, owns Multi-directional Redundant Skip (MRS) mechanism, which anticipates all zeros duplicate fields in advance. Thirdly, contains scheme transform The Calculation Format (TCF), transforms...
The paper presents a three-dimensional model of sodium-water reaction product transport in steam generators with small water/steam leak. is used to study the effects thermodynamic parameters Liquid Metal Fast Breeder Reactor (LMFBR) on leak response water detection system and optimize design. A hydrogen gas line density concept develop differential equation ion transport. can be applied analyze meters, oxygen meters other concentration-type systems. was verified injections into sodium...
Abstract Structural superlubricity (SSL) is a state of contact between two sliding surfaces with no wear and ultralow friction. SSL has been characterized at contacts van der Waals (vdW) layered materials, while its robustness under high pressure not assessed. Here we report experimental results showing that incommensurate vdW interfaces graphite can maintain the lower than 9.45 GPa, tungsten tip substrate remains stable up to 3.74 even higher strength most solids. Beyond this critical...