A5003145621- Oral microbiology and periodontitis research
- Dental Health and Care Utilization
- Pancreatic and Hepatic Oncology Research
- Sarcoma Diagnosis and Treatment
- HIV/AIDS oral health manifestations
- Ferroptosis and cancer prognosis
- Animal Virus Infections Studies
- Bone Tumor Diagnosis and Treatments
- SARS-CoV-2 and COVID-19 Research
- Dental Research and COVID-19
- Gastrointestinal Tumor Research and Treatment
- Lymphoma Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Cancer Genomics and Diagnostics
- Hand Gesture Recognition Systems
- Esophageal Cancer Research and Treatment
- Advanced Image Fusion Techniques
- Myasthenia Gravis and Thymoma
- Gait Recognition and Analysis
- Salivary Gland Disorders and Functions
- Biofield Effects and Biophysics
- Embedded Systems and FPGA Design
- Ocular and Laser Science Research
- Cancer-related gene regulation
- Autoimmune Bullous Skin Diseases
Shanghai Fudan Microelectronics (China)
2024
Fudan University
2019-2024
Shanghai Changzheng Hospital
2017-2024
Nantong University
2022-2024
Nanjing University of Chinese Medicine
2024
Taizhou People's Hospital
2024
Fudan University Shanghai Cancer Center
2022-2023
Second Military Medical University
1987-2023
Ethics and Public Policy Center
2023
Weatherford College
2023
Abstract Bingpian is a time‐honored herb in traditional Chinese medicine ( TCM ). It an almost pure chemical with composition of (+)‐borneol and has been historically used as topical analgesic for millennia. However, the clinical efficacy borneol lacks stringent evidence‐based studies verifiable scientific mechanism. We examined randomized, double‐blind, placebo‐controlled study involving 122 patients postoperative pain. Topical application led to significantly greater pain relief than...
Late mortality risk in sepsis-survivors persists for years with high readmission rates and low quality of life. The present study seeks to link the clinical heterogeneity distinct biological profiles at ICU discharge late adverse events using an unsupervised analysis.In original FROG-ICU prospective, observational, multicenter study, intensive care unit (ICU) patients sepsis on admission (Sepsis-3) were identified (N = 655). Among them, 467 discharged alive from included current study....
Subclassification of tumors based on molecular features may facilitate therapeutic choice and increase the response rate cancer patients. However, highly complex cell origin involved in osteosarcoma (OS) limits utility traditional bulk RNA sequencing for OS subclassification. Single-cell (scRNA-seq) holds great promise identifying heterogeneity. this technique has rarely been used study tumor By analyzing scRNA-seq data six conventional nine cancellous bone (CB) samples, we identified 29...
The recently emerged Omicron subvariants XBB and BQ.1.1 have presented striking immune evasion against most monoclonal neutralizing antibodies convalescent plasma. Therefore, it is essential to develop broad-spectrum COVID-19 vaccines combat current future emerging variants. Here, we found that the human IgG Fc-conjugated RBD of original SARS-CoV-2 strain (WA1) plus a novel STING agonist-based adjuvant CF501 (CF501/RBD-Fc) could induce highly potent durable broad-neutralizing antibody (bnAb)...
Studies have been rarely conducted to provide a comprehensive perspective of pregnant women with the intention investigate relationships between periodontal conditions and oral health-related quality life (OHRQoL). As such, this study aimed describe OHRQoL in Shanghai, China women.A cross-sectional was amongst all stages pregnancy China. Clinical examinations were performed assess conditions, including tooth loss, visible plaque index, bleeding on probing, probing pocket depth clinical...
Viral haemorrhagic disease (VHD) is a new and severe infectious of rabbits, with high rate morbidity mortality. The occurs throughout the year, affecting only adult rabbits not other domestic animals, fowls or laboratory rodents. transmission horizontal, by direct indirect contact, through all routes. There no evidence congenital infection biological vectors. causative agent, viral virus (VHDV), present in tissues, excretions secretions. It an icosahedral nonenveloped parvo-like virus....
Little is known about herpesvirus and putative periodontopathic bacteria in maternal chronic periodontitis. The present case-control study aimed to explore the potential relationship between herpesviruses periodontitis.Saliva samples were collected from 36 pregnant women with periodontitis (cases) healthy periodontal status (controls). Six (Porphyromonas gingivalis [Pg], Aggregatibacer actinomycetemcomitans [Aa], Fusobacterium nucleatum [Fn], Prevotella intermedia [Pi], Tannerella forsythia...
Background: Solitary spinal metastasis (SM) is one of the indications for total en bloc spondylectomy (TES). Conventional TES carries risk damage to great vessels anterior vertebral column, mainly because a lack visualization structures. In this study, we devised modified standard technique achieve direct in 1-stage posterior approach. Methods: Included study were patients ≥18 years old with solitary thoracic or lumbar SM who underwent at our institution between January 2017 and October...
Background. Ferroptosis has gained significant attention from oncologists as a vital outcome of oxidative stress. The aim this study was to develop prognostic signature that based on the ferroptosis-related genes (FRGs) for osteosarcoma patients and explore their specific role in osteosarcoma. Methods. training cohort dataset extracted Therapeutically Applicable Research Generate Effective Treatments (TARGET) database. Different techniques like univariate Cox regression, least absolute...
The peptide-based pan-coronavirus fusion inhibitor EK1 is in phase III clinical trials, and it has, thus far, shown good application prospects against SARS-CoV-2 its variants. To further improve vivo long-acting property, we herein developed an Fc-binding strategy by conjugating with human immunoglobulin G peptide (IBP), which can exploit the long half-life advantage of IgG vivo. newly engineered IBP-EK1 showed potent broad-spectrum inhibitory activity variants, including various Omicron...
To clarify the epidemiology, treatment, and prognosis of sarcomas occurring in bones joints. The surveillance, end results (SEER) 18 registries, comprising sarcoma diagnoses made between 2008 2014, were queried for arising or Kaplan-Meier analysis, multivariate logistic regression Cox proportional hazards model, nomograms used to identify prognostic factors. 2794 patients aged from 1 99 (55.8% male) with microscopically confirmed diagnosed as (including osteosarcoma, chondrosarcoma, Ewing...
Abstract Objective To investigate the disparity in dental caries between native and migrant children Shanghai, China. Methods Between 2013 2015, a random cluster sample of aged 5, 9, 12 15 years was collected from each district Shanghai. Oral examination performed following World Health Organization (WHO) method, findings were reported as decayed‐missing‐filled teeth primary dentition (dmft) permanent (DMFT). Results A total 10 150 examined, 33.6% them migrants. Migrant had higher prevalence...
This study aimed to design a nomogram survival prediction by means of the figures retrieved from Surveillance, Epidemiology, and End Results (SEER) source bank, predict overall (OS) patients with stage IIA non-small cell lung cancer (NSCLC) after surgery.Data for 4511 who had been diagnosed postoperative NSCLC were collected SEER databank, while information on 528 was acquired Chongqing University Cancer Hospital external validation cohort. The independent risk factors that affected...
Objective: To explore the effects of Lidan Huashi Pills on glutathione peroxidase (GSH-Px) activity and growth calcium oxalate crystals in kidneys rats. Methods: 30 rats were randomly divided into a blank group, model an experimental with 10 each group. The group was free to eat drink water for 8 weeks; ethylene glycol method used standard crystal modeling control 4 weeks. given feeding physiological saline (2 ml/d) by continuous gavage (450 mg/kg, 2 After weeks, all euthanized, left kidney...
Video-assisted thoracoscopic surgery (VATS) for a relatively large mediastinal tumor (5.0–10.0 cm) remains controversial. In addition, few studies have focused on comparing different surgical approaches tumors. Therefore, this study aimed to compare the short-term outcomes between subxiphoid approach VATS, intercostal and traditional sternotomy large-sized anterior The consecutively enrolled 159 patients with tumors who received in our hospital January 2018 July 2022 (subxiphoid VATS: 52...
Increasingly extranodal marginal B-cell lymphoma of mucosa-associated lymphoid tissue, known as tissue (MALT) lymphoma, is a type non-Hodgkin's lymphoma. The prognosis primary gastric MALT (GML) patients can be affected by many factors. Clinical risk factors, including age, therapy, sex, stage and family hematologic malignancy history, also have significant effects on the development disease. available data are mainly focused epidemiology; in contrast, few studies investigated prognostic...
Zhao Yizhen (?–1382) was one of the most important figures in history Daoism Yuan and Ming Dynasties. His master, Zhang Tianquan (1275–?), recorded to be a disciple Jin Pengtou (?–1341), famous master inner alchemy late Yuan, poems written by himself biography Yuchu (1359–1410), 43rd Heavenly Master. According these records, we know that Method learned from only about alchemy, inherited Pengtou. But this story does not include all facts. Since have found Tianquan, which is preserved rare...