Jia Lin

ORCID: 0000-0001-8557-1942
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About
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Research Areas
  • Gastric Cancer Management and Outcomes
  • Advanced biosensing and bioanalysis techniques
  • Family Support in Illness
  • Gastrointestinal Tumor Research and Treatment
  • Virology and Viral Diseases
  • Cancer survivorship and care
  • Inflammatory Biomarkers in Disease Prognosis
  • Virus-based gene therapy research
  • Cell Adhesion Molecules Research
  • Esophageal and GI Pathology
  • Signaling Pathways in Disease
  • Biosensors and Analytical Detection
  • Viral Infectious Diseases and Gene Expression in Insects
  • Peptidase Inhibition and Analysis
  • Metastasis and carcinoma case studies
  • NF-κB Signaling Pathways
  • Neurogenetic and Muscular Disorders Research
  • RNA Interference and Gene Delivery
  • Advanced Biosensing Techniques and Applications
  • Neonatal and Maternal Infections
  • Electrochemical sensors and biosensors
  • Metabolomics and Mass Spectrometry Studies
  • Health Promotion and Cardiovascular Prevention
  • T-cell and B-cell Immunology
  • MicroRNA in disease regulation

Fujian Medical University
2014-2025

Union Hospital
2018-2025

Fujian University of Traditional Chinese Medicine
2020-2024

Children's Hospital of Fudan University
2021-2024

East China University of Science and Technology
2019-2023

Fuzhou University
2020

Fujian Provincial Cancer Hospital
2016

Abstract Objective Demoralization has garnered increasing attention in recent years as a significant psychological distress. This study aims to identify latent classes of demoralization lung cancer patients using Latent Class Analysis (LCA) from person‐centered perspective and explore the factors influencing demoralization. Methods A cross‐sectional convenience sampling was conducted among 567 three tertiary hospitals China. LCA employed classify heterogeneous Multinomial logistic regression...

10.1002/pon.6312 article EN Psycho-Oncology 2024-03-01

The increasing genomic complexity of acute myeloid leukemia (AML), the most common form leukemia, poses a major challenge to its therapy. To identify potent therapeutic targets with ability block multiple cancer-driving pathways is thus imperative. unique peptidyl-prolyl cis-trans isomerase Pin1 has been reported promote tumorigenesis through upregulation numerous pathways. Although key drug target for treating promyelocytic (APL) caused by fusion oncogene, much less known about role in...

10.1186/s13045-018-0611-7 article EN cc-by Journal of Hematology & Oncology 2018-05-30

Background: Learning curves have been used in the field of robotic gastrectomy (RG). However, it should be noted that previous study did not comprehensively investigate all changes related to learning curve. This aims establish a curve for radical RG and evaluate its effect on short-term outcomes patients with gastric cancer. Methods: The clinicopathological data 527 who underwent between August 2016 June 2021 were retrospectively analyzed. operation time postoperative hospital stay...

10.1097/js9.0000000000001652 article EN cc-by-nc-nd International Journal of Surgery 2024-05-22

A photoelectrochemical immunoassay was devised to detect CA-125 employing enzyme-catalyzed precipitation on hollow porous In 2 O 3 nanotubes with CdS nanoparticles.

10.1039/d4ay00984c article EN Analytical Methods 2024-01-01

Chicken embryo fibroblast DF-1 cells are increasingly being used in the production of avian virus vaccines. However, relatively low proliferative capacity does not meet requirements industrial production. In this study, we attempted to improve cells. The results intracellular metabolomics showed that 28 types metabolites could play roles cell growth based on variance and timing analysis from grown two media with distinct difference, DMEM/F12 (1 : 1) DMEM. By examining differences components...

10.1039/c9ra05128g article EN cc-by-nc RSC Advances 2019-01-01

The value of plasma fibronectin (pFN) in the diagnosis and prognosis sepsis has not been fully established. Previous studies finding that pFN is significantly reduced sepsis, however, whether pFn affects clarified. Here, we detected analyzed other conventional inflammatory markers advanced patients performed correlation analysis with SOFA score. We also used Fn gene conditional knockout mice which were by cecum ligation puncture (CLP) to investigate effect FN deficiency on prognosis. found,...

10.1096/fj.202100760rrr article EN cc-by-nc The FASEB Journal 2022-02-19

Fibronectin (FN) is a multi-functional glycoprotein that primarily acts as cell adhesion molecule and tethers cells to the extra cellular matrix. In order clarify effect of FN deficiency on hematopoiesis, biochemical immune parameters in mice. We constructed tamoxifen-induced conditional (cre-loxp system) fibronectin knock-out (FnKO) mouse model C57BL/6 background, monitored their behavior, fertility, histological, hematopoietic, immunological indices. found Fn KO mice had reduced high...

10.7717/peerj.10224 article EN cc-by PeerJ 2020-10-30

Objective Cancer burden can be reduced when the population's knowledge of cancer prevention and control measures is increased. However, current epidemiological research investigating in China limited. This study aimed to examine core levels as well its influencing factors among adults Fujian, China. Study design A cross-sectional study. Methods From September December 2021, a total 2,440 Chinese urban rural from Fujian Province, located Southeastern China, were randomly selected for this The...

10.3389/fpubh.2022.1053183 article EN cc-by Frontiers in Public Health 2022-12-21

A novel capacitance immunosensor based on DNAzyme concatemer-amplified signal-generation tags was developed for the sensitive detection of interleukin-6 (IL-6) an interdigitated micro-comb electrode.

10.1039/d0nj05507g article EN New Journal of Chemistry 2020-12-09

The efficacy and benefits of adjuvant chemotherapy (AC) for patients with gastric cancer pT3N0M0 remain controversial.We prospectively collected retrospectively analyzed 235 who underwent radical resection between February 2010 January 2016. Patients were divided into two groups: the surgery-alone (SA) group (n = 82) AC 153). We effects on overall survival (OS) recurrence-free (RFS), relationship number cycles (CC) recurrence rate (RR).The 5-year OS RFS participants 80.9% 87.7%,...

10.3389/fonc.2021.712432 article EN cc-by Frontiers in Oncology 2021-08-26

Objective To investigate resourcefulness and mental health of young patients with breast cancer, evaluate their correlation. Methods A total 52 cases met the inclusion exclusion criteria for cancer were enrolled in study. General condition questionnaire, Chinese Version Resourcefulness Scale Symptom Checklist (SCL-90) used, patients′ its related factors investigated. Results Resourcefulness was (62.7±21.7), which (35.6±11.9) personal resourcefulness, (27.2 ±11.3) social...

10.3760/cma.j.issn.1674-2907.2016.11.003 article EN Zhonghua xiandai huli zazhi 2016-04-16
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