A5022123482- Health, Environment, Cognitive Aging
- Birth, Development, and Health
- Air Quality and Health Impacts
- Prenatal Substance Exposure Effects
- Effects and risks of endocrine disrupting chemicals
- Food Security and Health in Diverse Populations
- Child Abuse and Trauma
- Climate Change and Health Impacts
- Maternal Mental Health During Pregnancy and Postpartum
- Migration, Health and Trauma
- Energy and Environment Impacts
- Toxic Organic Pollutants Impact
- Psychological and Temporal Perspectives Research
- COVID-19 and Mental Health
- Health disparities and outcomes
University of California, San Francisco
2021-2024
Exposures early in life, beginning utero, have long-term impacts on mental and physical health. The ECHO prenatal childhood pathways to health consortium (ECHO-PATHWAYS) was established examine the independent combined impact of pregnancy chemical exposures psychosocial stressors child neurodevelopment airway health, as well placental mechanisms underlying these associations.The ECHO-PATHWAYS harmonises extant data from 2684 mother-child dyads three cohort studies (CANDLE [Conditions...
Animal and epidemiological studies suggest that prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) may negatively impact toddler neurodevelopment.We investigated this association in 835 mother-child pairs from CANDLE, a diverse pregnancy cohort the mid-South region of U.S. PAH metabolite concentrations were measured mid-pregnancy maternal urine. Cognitive Language composite scores at ages 2 3 years derived Bayley Scales Infant Toddler Development, 3rd edition (Bayley-3). Behavior...
Abstract Women’s social experiences can have long-term implications for their offspring’s health, but little is known about the potential independent contributions of multiple periods stress exposures over time. This study examined associations maternal exposure to adversity in childhood and pregnancy with children’s anxiety depression symptoms a large, sociodemographically diverse sample. Participants were 1389 mother-child dyads (child age M = 8.83 years; SD 0.66; 42% Black, White; 6%...
Epidemiological study findings are inconsistent regarding associations between prenatal polycyclic aromatic hydrocarbon (PAH) exposures and childhood behavior. This examined of PAH exposure with behavior at age 4-6 years in a large, diverse, multi-region prospective cohort. Secondary aims included examination mixtures effect modification by child sex, breastfeeding, neighborhood opportunity. The ECHO PATHWAYS Consortium pooled 1118 mother-child dyads from three pregnancy cohorts six U.S....
Importance Few population-based studies in the US collected individual-level data from families during COVID-19 pandemic. Objective To examine differences pandemic–related experiences a large sociodemographically diverse sample of children and caregivers. Design, Setting, Participants The Environmental influences on Child Health Outcomes (ECHO) multi-cohort consortium is an ongoing study that brings together 64 individual cohorts with participants (24 757 31 700 caregivers this study) all 50...
Background: Executive function, which develops rapidly in childhood, enables problem-solving, focused attention, and planning. Animal models describe executive function decrements associated with ambient air pollution exposure, but epidemiologic studies are limited. Methods: We examined associations between early childhood exposure school-aged 1235 children from three US pregnancy cohorts the ECHO-PATHWAYS Consortium. derived point-based residential exposures to particulate matter ≤2.5 µm...
Executive functions develop rapidly in childhood, enabling problem-solving, focused attention, and planning. Exposures to environmental toxicants pregnancy may impair healthy executive function development children. There is increasing concern regarding polycyclic aromatic hydrocarbons (PAHs) given their ability transfer across the placenta fetal blood-brain barrier, yet evidence from epidemiological studies limited.
Background and Aims: Prior studies examining the association between spatiotemporally resolved air pollution child executive function (working memory, inhibitory control, cognitive flexibility) are limited. We aimed to fill this gap using data from ECHO-PATHWAYS Consortium. Methods: included 1,241 children three U.S. pregnancy cohorts (CANDLE, TIDES, GAPPS). Exposure particulate matter ≤2.5μm in aerodynamic diameter (PM₂.₅), nitrogen dioxide (NO₂), ozone (O₃) at age 0-4 were derived...
BACKGROUND AND AIM: Epidemiological study findings are inconsistent regarding associations between prenatal polycyclic aromatic hydrocarbon (PAH) exposures and childhood behavior. This examined the of PAH exposure with behavior at age 4-6 years in a large, diverse, multi-region prospective cohort. Secondary aims included examination mixtures effect modification by child sex, breastfeeding, neighborhood opportunity. METHODS: The ECHO PATHWAYS Consortium pooled 1113 mother-child dyads from...