Knut‐Arne Wensaas

ORCID: 0000-0001-9113-7843
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About
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Research Areas
  • Gastrointestinal motility and disorders
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Viral gastroenteritis research and epidemiology
  • Respiratory viral infections research
  • Parasitic Infections and Diagnostics
  • COVID-19 and Mental Health
  • Salmonella and Campylobacter epidemiology
  • Dysphagia Assessment and Management
  • Child Nutrition and Feeding Issues
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 and healthcare impacts
  • Whipple's Disease and Interleukins
  • Vaccine Coverage and Hesitancy
  • Helicobacter pylori-related gastroenterology studies
  • Musculoskeletal pain and rehabilitation
  • Long-Term Effects of COVID-19
  • Pediatric health and respiratory diseases
  • Dermatological diseases and infestations
  • Pneumonia and Respiratory Infections
  • Nutrition and Health in Aging
  • Respiratory and Cough-Related Research
  • Health, psychology, and well-being
  • Clostridium difficile and Clostridium perfringens research
  • Emergency and Acute Care Studies
  • Viral Infections and Outbreaks Research

NORCE Norwegian Research Centre
2018-2024

Hospital for Tropical Diseases
2021

Haukeland University Hospital
2021

University of Oslo
2019-2020

Central Norway Regional Health Authority
2020

University of Bergen
2007-2018

Uni Research (Norway)
2009-2018

VID Specialized University
2017

Institutt for Eksperimentell Medisinsk Forskning
2011

Primary Health Care
2008-2011

Chris Eijsbouts Tenghao Zheng Nicholas A. Kennedy Ferdinando Bonfiglio Carl A. Anderson and 95 more Loukas Moutsianas Jo Holliday Jingchunzi Shi Suyash Shringarpure Michelle Agee Stella Aslibekyan Adam Auton Robert K. Bell Katarzyna Bryc Sarah Clark Sarah L. Elson Kipper Fletez‐Brant Pierre Fontanillas Nicholas A. Furlotte Pooja Gandhi Karl Heilbron Barry Hicks David A. Hinds Karen E. Huber Ethan M. Jewett Yunxuan Jiang Aaron Kleinman Keng‐Han Lin Nadia K. Litterman Marie K. Luff Jey C. McCreight Matthew H. McIntyre Kimberly F. McManus Joanna L. Mountain Sahar V. Mozaffari Priyanka Nandakumar Elizabeth S. Noblin Carrie A. M. Northover Jared O’Connell Aaron A. Petrakovitz Steven J. Pitts G. David Poznik J. Fah Sathirapongsasuti Anjali J. Shastri Janie F. Shelton Chao Tian Joyce Y. Tung Robert J. Tunney Vladimir Vacic Xin Wang Amir S. Zare Alexandru-Ioan Voda Purna Kashyap Lin Chang Emeran A. Mayer Margaret Heitkemper Gregory S. Sayuk Tamar Ringel‐Kulka Yehuda Ringel William D. Chey Shanti Eswaran Juanita L. Merchant Robert J. Shulman Luís Bujanda Koldo García‐Etxebarria Aldona Dlugosz Greger Lindberg Peter T. Schmidt Pontus Karling Bodil Ohlsson Susanna Walter Åshild Faresjö Magnus Simrén Jonas Halfvarson Piero Portincasa Giovanni Barbara Paolo Usai–Satta Matteo Neri Gerardo Nardone Rosario Cuomo Francesca Galeazzi Massimo Bellini Anna Latiano Lesley A. Houghton Daisy Jonkers Alexander Kurilshikov Rinse K. Weersma Mihai G. Netea Jonas Tesarz Annika Gauss Miriam Goebel‐Stengel Viola Andresen Thomas Frieling Christian Pehl Rainer Schaefert Beate Niesler Wolfgang Lieb Kurt Hanevik Nina Langeland Knut‐Arne Wensaas

Abstract Irritable bowel syndrome (IBS) results from disordered brain–gut interactions. Identifying susceptibility genes could highlight the underlying pathophysiological mechanisms. We designed a digestive health questionnaire for UK Biobank and combined identified cases with IBS independent cohorts. conducted genome-wide association study 53,400 433,201 controls replicated significant associations in 23andMe panel (205,252 1,384,055 controls). Our confirmed six genetic loci IBS. Implicated...

10.1038/s41588-021-00950-8 article EN cc-by Nature Genetics 2021-11-01

<h3>Background</h3> <i>Giardia lamblia</i> is a common cause of gastroenteritis worldwide, but there limited knowledge about the long-term complications. <h3>Objective</h3> To estimate relative risk irritable bowel syndrome (IBS) and chronic fatigue 3 years after acute giardiasis. <h3>Design</h3> Controlled historic cohort study with years9 follow-up. Data collected by mailed questionnaire. <h3>Setting</h3> Waterborne outbreak giardiasis in city Bergen, Norway. <h3>Participants</h3> 817...

10.1136/gutjnl-2011-300220 article EN Gut 2011-09-12

Giardia infection in a nonendemic setting is associated with an increased risk for irritable bowel syndrome and chronic fatigue 6 years later. These conditions should be considered differential diagnosis patients persisting symptoms after eradication of the parasite. Background. Functional gastrointestinal disorders may follow acute infections. This study aimed to estimate persistence, prevalence, infection. Methods. We performed controlled prospective cohort 1252 individuals who had...

10.1093/cid/ciu629 article EN cc-by-nc-nd Clinical Infectious Diseases 2014-08-12

The comparative effectiveness of sigmoidoscopy and fecal immunochemical testing (FIT) for colorectal cancer (CRC) screening is unknown.Individuals aged 50-74 years living in Southeast Norway were randomly invited between 2012 2019 to either once-only flexible or FIT every second year. Colonoscopy was recommended after if any polyp ≥10 mm, ≥3 adenomas, advanced CRC found or, subsequent to, >15 μg hemoglobin/g feces. Data this report obtained complete recruitment both groups included 2 full...

10.1053/j.gastro.2020.11.037 article EN cc-by Gastroenterology 2020-11-21

Through the INTernational ConsoRtium of Primary Care BIg Data Researchers (INTRePID), we compared pandemic impact on volume primary care visits and uptake virtual in Australia, Canada, China, Norway, Singapore, South Korea, Sweden, UK USA.Visit definitions were agreed centrally, implemented locally across various settings INTRePID countries, weekly visit counts shared centrally for analysis. We evaluated rate physician during 2019 2020. Rate ratios (RRs) total proportion that period 2020...

10.1136/bmjopen-2021-059130 article EN cc-by-nc BMJ Open 2022-05-01

Irritable bowel syndrome (IBS) is a complication that can follow gastrointestinal infection, but it not clear if patients also develop chronic fatigue. We investigated the prevalence and odds ratio of IBS fatigue 10 years after an outbreak Giardia lamblia, compared with control cohort, changes in over time.We performed prospective follow-up study 1252 laboratory-confirmed cases giardiasis (exposed), which developed Bergen, Norway 2004. Statistics provided us information from 2504 unexposed...

10.1016/j.cgh.2018.01.022 article EN cc-by-nc-nd Clinical Gastroenterology and Hepatology 2018-03-06

A high prevalence of chronic fatigue has previously been reported following giardiasis after a large waterborne outbreak in Bergen, Norway 2004. The aim this study was to describe and evaluate differential diagnoses natural course five years among patients who three the infection. Patients Giardia infection met Chalder's criteria for (n=347) questionnaire all had laboratory confirmed during Bergen (n=1252) were invited participate (n=253). Structured interviews clinical examination performed...

10.1186/1471-230x-13-28 article EN cc-by BMC Gastroenterology 2013-02-12

Background Some psychiatric disorders have been associated with increased risk of miscarriage. However, there is a lack studies considering broader spectrum to clarify the role common as opposed independent mechanisms. Aims To examine miscarriage among women diagnosed conditions. Method We studied registered pregnancies in Norway between 2010 and 2016 ( n = 593 009). The birth registry captures ending gestational week 12 or later, patient general practitioner databases were used identify...

10.1192/bjp.2020.259 article EN The British Journal of Psychiatry 2021-01-15

A high rate of post-infectious fatigue and abdominal symptoms two years after a waterborne outbreak giardiasis in Bergen, Norway 2004 has previously been reported. The aim this report was to identify risk factors associated with such manifestations.All laboratory confirmed cases (n = 1262) during the Bergen received postal questionnaire after. Degree fatigue, as well previous problems, recorded. In statistical analyses number treatment courses, refractory infection, delayed education sick...

10.1186/1471-2334-9-206 article EN cc-by BMC Infectious Diseases 2009-12-01

The aim of this study was to evaluate the prevalence fatigue and abdominal symptoms 2 years after Giardia lamblia infection. All 1262 cases who had Giardia-positive stool samples during an outbreak in 2004 Norway received a questionnaire 2006 asking about symptoms. Fatigue reported by 41%, whereas 38% symptoms, there highly significant association between these Increasing age risk factor for fatigue. were not due chronic infection cohort. Our data warrant further investigations into late...

10.1016/j.trstmh.2009.01.010 article EN Transactions of the Royal Society of Tropical Medicine and Hygiene 2009-01-31

Increased risk of miscarriage has been reported for women with specific chronic health conditions. A broader investigation diseases and may uncover patterns across categories illness. The objective this study was to the according various preexisting diseases.We conducted a registry-based study. Registered pregnancies (n = 593,009) in Norway between 2010 2016 were identified through 3 national registries (birth register, general practitioner data, patient registries). Six broad illness...

10.1371/journal.pmed.1003603 article EN public-domain PLoS Medicine 2021-05-10

To investigate in a cohort with previous gastrointestinal infection and control group the prevalence of overactive bladder syndrome (OAB), how it was associated three other functional disorders; irritable bowel (IBS), dyspepsia (FD) chronic fatigue (CF).Controlled historic study including 724 individuals laboratory confirmed giardiasis six years earlier, 847 controls matched by gender age. Prevalence odds ratios (OR) 95 % confidence intervals (CI) were calculated.The OAB 18.7 (134/716)...

10.1186/s12876-015-0296-0 article EN cc-by BMC Gastroenterology 2015-06-10

The majority of patients with irritable bowel syndrome (IBS) are diagnosed and treated in primary care. aim this study was to investigate the implementation Rome criteria daily care clinical practice adherence general practitioners (GPs) recommended diagnostic approaches for IBS.A survey consisting 18 questions distributed across 11 European countries used assess GPs' approach IBS, use perspective on aetiology disorder.Overall, 185 GPs completed survey. In practice, 32% reported that they...

10.1097/meg.0000000000000848 article EN European Journal of Gastroenterology & Hepatology 2017-01-25

Abstract Background and aims The ACR1990 criteria of fibromyalgia (FM) have been criticized due to poor reliability tender points counting (TPC), inconsistent definitions the widespread pain, by not considering other symptoms than pain in FM phenotype. Therefore, several newer self-report measures for emerged. aim this study was translate survey questionnaire (FSQ) Norwegian validate both 2011 2016 diagnostic (FSDC) against criteria. Methods One hundred twenty chronic patients formerly...

10.1515/sjpain-2020-0002 article EN cc-by Scandinavian Journal of Pain 2020-06-30

Studies have shown an increased prevalence of irritable bowel syndrome (IBS) after acute gastroenteritis. Food as a precipitating and perpetuating factor in IBS has gained recent interest, but food intolerance following gastroenteritis is less investigated. The aims this study were firstly, to compare perceived group previously exposed Giardia lamblia with control group; secondly, explore the relation status; thirdly, investigate associations content fermentable oligosaccharides,...

10.1186/s12876-015-0393-0 article EN cc-by BMC Gastroenterology 2015-11-19

Abstract Background Extensive use of antibiotics and the resulting emergence antimicrobial resistance is a major health concern globally. In Norway, 82% prescribed in primary care one four prescriptions are issued for treatment urinary tract infections (UTI). The aim this study was to investigate time trends antibiotic following consultation UTI care. Methods For period 2006–2015 we linked data from Norwegian Registry Control Payment Health Reimbursements on all patient consultations...

10.1186/s12875-021-01470-4 article EN cc-by BMC Family Practice 2021-06-24

Objectives. To document clinical characteristics of influenza-like illness, reported use health preventive measures and attitudes towards vaccination among patients with illness in general practice during the influenza pandemic 2009. Methods. Cross-sectional survey practice. Patients, who were identified as having peak activity Norway, eligible for inclusion study. A questionnaire was sent 2–4 weeks after visit to GP diagnosis October December 2009, from practices Norway. sample responders...

10.1093/fampra/cmr064 article EN Family Practice 2011-09-05

Irritable bowel syndrome (IBS) is a common complication following gastroenteritis, and high prevalence of postgiardiasis IBS has previously been reported. This study aims to investigate the prevalence, adjusted relative risk (RRadj), overlap different functional gastrointestinal disorders (FGID) according Rome III criteria infection with Giardia lamblia.All patients ≥18 years age verified giardiasis during an outbreak in 2004, control group matched by gender, were mailed questionnaire 3...

10.1111/nmo.12856 article EN Neurogastroenterology & Motility 2016-05-18

Abstract Background With Norwegian national registry data, we assessed the prevalence of post-COVID-19 symptoms at least 3 months after confirmed infection, and whether sociodemographic factors pre-pandemic health problems were risk for these symptoms. Methods All persons with a positive SARS-CoV-2 PCR test from February 2020 to 2021 (exposed) compared group without (unexposed) matched on age, sex, country origin. We used Cox regression estimate hazard ratios (HR) 18 outcome commonly...

10.1186/s12879-023-08727-6 article EN cc-by BMC Infectious Diseases 2023-10-25

Estimate prevalence of gestational diabetes mellitus (GDM) and its treatment in Norway 2010-2020 explore impact new national GDM guidelines 2017.

10.1016/j.diabres.2023.111025 article EN cc-by Diabetes Research and Clinical Practice 2023-11-22

Diverticular disease is a chronic and common condition, yet the impact of diverticular in primary care largely unknown. The diagnosis relies on demonstration diverticula colon, necessary investigations are often not available care. specificity sensitivity symptoms, clinical signs laboratory tests alone generally low consequently diagnostic process will be characterized by uncertainty. Also, criteria for symptomatic uncomplicated absence macroscopic inflammation clearly defined. Therefore...

10.1097/mcg.0000000000000596 article EN Journal of Clinical Gastroenterology 2016-09-13
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