Lisa Knight
- Diabetes Management and Research
- Diabetes and associated disorders
- Pancreatic function and diabetes
- Diabetes Treatment and Management
- Adolescent and Pediatric Healthcare
- Ethics in Clinical Research
- Food Security and Health in Diverse Populations
- Gun Ownership and Violence Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Asthma and respiratory diseases
- Adrenal and Paraganglionic Tumors
- Health and Medical Research Impacts
- Disaster Response and Management
- Hormonal Regulation and Hypertension
- Parvovirus B19 Infection Studies
- Cancer, Hypoxia, and Metabolism
- Hepatitis B Virus Studies
- Immunodeficiency and Autoimmune Disorders
- Suicide and Self-Harm Studies
- Pharmaceutical studies and practices
- Childhood Cancer Survivors' Quality of Life
- Vitamin D Research Studies
University of South Carolina
2014-2023
University of Florida
2017
OBJECTIVE To examine short-term mortality and cause of death among youth young adults (YYAs) with youth-onset diabetes. RESEARCH DESIGN AND METHODS We included 19,717 YYAs newly diagnosed diabetes before 20 years age from 1 January 2002 to 31 December 2015 enrolled in the SEARCH for Diabetes Youth Study. Of these, 14,721 had type 1; 4,141 2; 551 secondary 304 other/unknown type. Cases were linked National Death Index through 2017. calculated standardized ratios (SMRs) 95% CIs based on age,...
Pheochromocytoma and paraganglioma are rare in the pediatric population occurring approximately 1 50,000 children. While some cases sporadic, they have commonly been associated with syndromes such as von Hippel-Lindau, multiple endocrine neoplasia types IIa IIb, neurofibromatosis type 1, hereditary pheochromocytoma-paraganglioma syndromes. In children less than 18 years of age 60% pheochromocytomas paragangliomas a germline mutation. We present an 11-year-old child abdominal related to...
Abstract Type 1 diabetes (T1D) has a strong genetic component. The insulin dependent (Idd)22 locus was identified in crosses of T1D-susceptible NOD mice with the strongly T1D-resistant ALR strain. NODcALR-(D8Mit293-D8Mit137)/Mx (NOD-Idd22) recombinant congenic mouse strain generated which carry full Idd22 confidence interval. NOD-Idd22 exhibit almost complete protection from spontaneous T1D and significant reduction insulitis. Our goal to unravel mode Idd22-based using vivo vitro models. We...
Dyslipidemia has been documented in youth with type 2 diabetes. There is a paucity of studies examining dyslipidemia over time diabetes and associated risk factors.
Children with asthma and obesity are more likely to have lower vitamin D levels, but the optimal replacement dose is unknown in this population. The objective of study identifying a children obesity-related that safely achieves serum levels ≥ 40 ng/mL. This prospective multisite randomized controlled trial recruited children/adolescents body mass index 85% for age/sex. Part 1 (dose finding), evaluated 4 oral regimens 16 weeks identify achieved 2 compared calculated from part (50,000 IU...
OBJECTIVE To identify correlates of hemoglobin A1c (HbA1c) testing frequency and associations with HbA1c levels microvascular complications in youth-onset diabetes. RESEARCH DESIGN AND METHODS The SEARCH for Diabetes Youth study collected data from individuals diagnosed diabetes before age 20 at 8 years (n = 1,885 type 1, n 230 2) 13 649 84 duration. We identified reporting ≥3 tests/year using logistic regression. examined (retinopathy, neuropathy, or nephropathy) sequentially adjusted...
<p> </p> <p><strong>Objective:</strong> To evaluate the relation between household food insecurity (HFI) and fear of hypoglycemia among young adults with type 1 2 diabetes, adolescents their parents. <p><em><strong>Research Design Methods</strong></em><strong>:</strong> We analyzed cross-sectional data 1,676 youth-onset diabetes (84% 1, 16% 2) 568 (<18 years; mean age 15.1 years) from SEARCH for Diabetes in Youth...
<p> </p> <p><strong>Objective:</strong> To evaluate the relation between household food insecurity (HFI) and fear of hypoglycemia among young adults with type 1 2 diabetes, adolescents their parents. <p><em><strong>Research Design Methods</strong></em><strong>:</strong> We analyzed cross-sectional data 1,676 youth-onset diabetes (84% 1, 16% 2) 568 (<18 years; mean age 15.1 years) from SEARCH for Diabetes in Youth...