A5024043489- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Nerve injury and regeneration
- Cancer Immunotherapy and Biomarkers
- Vascular Procedures and Complications
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Treatments and Studies
- Liver Disease and Transplantation
- Hepatitis B Virus Studies
- Colorectal Cancer Surgical Treatments
- Anorectal Disease Treatments and Outcomes
- Hepatitis C virus research
- Central Venous Catheters and Hemodialysis
- Gut microbiota and health
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Neuroscience and Neural Engineering
- Muscle activation and electromyography studies
- Ferroptosis and cancer prognosis
- Ginger and Zingiberaceae research
- Liver Diseases and Immunity
- Enhanced Recovery After Surgery
- Orthopedic Surgery and Rehabilitation
- Genomics, phytochemicals, and oxidative stress
- Case Reports on Hematomas
- Chronic Kidney Disease and Diabetes
Xinxiang Medical University
2025
Tianjin Medical University Cancer Institute and Hospital
2020-2024
Xuzhou Medical College
2023-2024
Jiangsu University
2023-2024
Yangtze University
2023-2024
Zhejiang Cancer Hospital
2023
Zhejiang University
2023
Zunyi Medical University
2018-2022
Nanjing University of Chinese Medicine
2020-2022
Shanghai University of Traditional Chinese Medicine
2021-2022
Abstract Chemotherapy works synergistically with sonodynamic therapy in a multi‐functional system and is employed to improve the therapeutic outcomes of hepatocellular carcinoma. In this study, ultrasound‐responsive nanoparticles (USFNPs) are loaded dual drugs, doxorubicin, composite ultrasound‐sensitive agent, curcumin‐gold. The USFNPs modified an acid‐hydrolyzable polyethylene glycol outermost layer, making it stable blood normal tissues while peeling off acidic tumor microenvironment....
To investigate the impact of metabolic dysfunction-associated steatotic liver disease (MASLD) on efficacy immune checkpoint inhibitor (ICI)-based therapy in patients with chronic hepatitis B (CHB)-related hepatocellular carcinoma (HCC).
The oxidative stress response caused by traumatic brain injury (TBI) leads to secondary damage in the form of tissue and cell death. Nuclear transcription-related factor 2 (NRF2) is a key body against has an important role combating TBI neurons. In present study, we investigated whether rutaecarpine could activate PGK1/KEAP1/NRF2 pathway antagonize We performed controlled cortical impact (CCI) surgery on mice taken H O treatment PC12 cells construct models. results western blot showed that...
Targeted muscle reinnervation (TMR) is a microsurgical repair technique to reconstruct the anatomical structure between distal nerve and stump provide more myoelectric information artificially intelligent prosthesis. Postoperative functional electrical stimulation treatment of patient’s denervated or proximal as well growth factor injection effective in promoting regeneration function recovery. In this experiment, we successfully established TMR rat model divided Sprague-Dawley (SD) adult...
Abstract Background Effective systemic therapy remains limited for advanced esophageal squamous cell carcinoma (ESCC) and hepatocellular (HCC), particularly after prior failed treatment with immune checkpoint inhibitors (ICIs). Theoretically, a combination of tyrosine kinase (TKIs) ICIs may restore immunotherapy sensitivity. Methods In this phase 1b study, patients received AL2846, an antiangiogenic TKI multiple targets (c‐MET, VEGFR1, c‐KIT, Axl, RET, KDR, VEGFR3), in anti–PD‐L1 antibody...
One of the important advantages distal transradial access (dTRA) is significant reduction in incidence radial artery occlusion (RAO). There are few reports on influencing factors for (dRAO) after cardiovascular interventions via dTRA.This retrospective analysis included clinical data patients who underwent a intervention dTRA. The dRAO was evaluated by ultrasound within 24 hours procedure. Multivariate logistic used to explore dRAO.The 3.5% (28/805) at follow-up In comparison between 2...
The aim of this study was to compare the efficacy liver transplantation (LT) and resection (LR) for hepatocellular carcinoma (HCC) patients with portal vein tumor thrombus (PVTT) investigate risk factors affecting prognosis.A total 94 HCC PVTT type I (segmental PVTT) II (lobar were involved divided into LR (n=47) LT groups (n=47). Recurrence-free survival (RFS) overall (OS) compared before after inverse probability treatment weighting (IPTW). Prognostic RFS OS explored.Two well-balanced...
Targeted muscle reinnervation (TMR) is a surgical procedure used to transfer residual peripheral nerves from amputated limbs targeted muscles, which allows the target muscles become sources of motor control information for function reconstruction. However, effect TMR on injured neurons still unclear. In this study, we aimed explore hind limb surgery in spinal cord rats after tibial nerve transection. We found that reduction and atrophy mice caused by transection improved TMR. enhanced...
Veins are easy to obtain, have low immunogenicity, and induce a relatively weak inflammatory response. Therefore, veins the potential be used as conduits for nerve regeneration. However, because of presence venous valves great elasticity wall, vein is not conducive In this study, novel tissue engineered graft was constructed by combining normal dissected microtissue with an autologous repairing 10-mm peripheral defects in rats. Compared rats given alone, had improved sciatic static index,...
Background: Assessing the size of distal radial artery (DRA) in anatomic snuffbox (AS) before coronary intervention is extremely important selection suitable patients, improving success rate puncture and reducing complications. Objective: To evaluate diameter DRA AS its influencing factors Chinese patients scheduled for intervention. Methods: Ultrasound was used to detect inner vessels. A total 1182 were involved study. Results: In all mean diameters DRA, conventional (CRA) ulnar (UA) 2.00 ±...
Purpose We evaluated the clinical effect of utilizing a Limberg rhomboid flap graft in conjunction with Enhanced Recovery After Surgery (ERAS) protocols for management pilonidal sinus sacrococcygeal region to demonstrate feasibility applying ERAS treatment sinus. Methods Between January 2010 and August 2018, prospective data analysis was undertaken on 109 patients who received surgical at Department Colorectal Anal Surgery, Jingzhou Hospital affiliated Yangtze University, Taizhou Affiliated...
BackgroundThere is a lack of randomized clinical trials on whether the 6-French (Fr) Glidesheath Slender (GSS; Terumo, Tokyo, Japan) superior to 6-Fr conventional radial sheath (CS) with respect early-term incidence distal artery occlusion (dRAO) in patients who have undergone coronary angiography (CAG) and/or percutaneous intervention (PCI) via transradial access.MethodsThis was prospective, single-centre trial were undergo CAG PCI either GSS or CS. The primary end point dRAO at 24 hours...
Objective This study aimed to investigate serum levels of the cystatin C (CysC)/creatinine (Cr) ratio and renal markers (CysC, Cr, urea, uric acid [UA]) for different ages by sex. We also establish pediatric reference intervals CysC/Cr ratio. Methods Serum samples were collected from 4765 healthy children (0–18 years old). function measured, each participant was calculated statistically analyzed. Results The marker CysC did not substantially change after 1 year old. UA generally increased...
Oxaliplatin can cause severe peripheral neurotoxicity, which is an important reason for clinical oxaliplatin reduction and cessation of treatment. induced neurotoxicity (OIPN) paresthesia dysesthesia, even affect the quality life patients. So far, there are no recognized effective measures to prevent OIPN. Huangqi Guizhi Wuwu decoction a classical prescription ancient Chinese medicine recorded in "the synopsis Golden Chamber," be used treatment various neurotoxicity. However, lack...
Purpose To investigate the value of modified Bacon operation in patients with low rectal cancer. Methods Retrospective analysis 60 treated laparoscopic surgery for cancer Department Colorectal and Anal Surgery, Jingzhou Hospital affiliated to Yangtze University, from 2019 2022, divided into observation control groups based on method (laparoscopic group Dixon prophylactic ileostomy group). We compared variations between two groups. Results The length abdominal surgical incision was shorter...
Background. Hepatocellular carcinoma (HCC) is one of the most aggressive malignancies with poor prognosis. There are many selectable treatments good prognosis in Barcelona Clinic Liver Cancer- (BCLC-) 0, A, and B HCC patients, but crucial factor affecting survival high recurrence rate after treatments. Therefore, it great significance to predict BCLC-0, BCLC-A, BCLC-B patients. Aim. To develop a gene signature enhance prediction among Materials Methods. The RNA expression data clinical...
This study aimed to investigate the colonization and prevalence of carbapenem-resistant Enterobacteriaceae (CRE) in pediatric liver transplant recipients analyze high-risk factors prognosis CRE infection.A prospective involving 152 patients undergoing transplantation was carried out. Anal swab bacteria cultures were collected when entered intensive care unit (ICU) they left order screen for intestinal colonization. The results grouped according occurrence infection following surgery, divided...
Treatments for patients with early-stage hepatocellular carcinoma (HCC) include liver transplantation (LT), resection (LR), radiofrequency ablation (RFA), and microwave (MWA), are critical their long-term survival. However, a computational model predicting treatment-independent prognosis of HCC, such as overall survival (OS) recurrence-free (RFS), is yet to be developed, our best knowledge. The goal this study identify prognostic factors associated OS RFS in HCC develop nomograms predict...
Abstract Background Liver transplantation (LT), resection (LR), and ablation (LA) are three curative‐intent treatment options for patients with early hepatocellular carcinoma (HCC). We aimed to develop a prognostic calculator compare the long‐term outcomes following each of these therapies. Methods A total 976 HCC within Milan criteria who underwent LT, LR, LA between 2009 2019 from four institutions were evaluated. Multistate competing risks prediction models recurrence‐free survival (RFS),...