A5046506106- Plant Molecular Biology Research
- Photosynthetic Processes and Mechanisms
- Alkaloids: synthesis and pharmacology
- RNA and protein synthesis mechanisms
- Plant Reproductive Biology
- Plant Virus Research Studies
- RNA modifications and cancer
- Plant pathogens and resistance mechanisms
- Plant nutrient uptake and metabolism
- Plant-Microbe Interactions and Immunity
- Chromosomal and Genetic Variations
- Genomics and Chromatin Dynamics
- Legume Nitrogen Fixing Symbiosis
- Genomics and Phylogenetic Studies
- Berberine and alkaloids research
- Plant Gene Expression Analysis
- RNA Research and Splicing
- Plant Parasitism and Resistance
- Single-cell and spatial transcriptomics
- Plant Pathogenic Bacteria Studies
- Photoreceptor and optogenetics research
- Insect symbiosis and bacterial influences
- Natural product bioactivities and synthesis
- Sulfur Compounds in Biology
- Insect and Pesticide Research
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2022-2025
Plant Health Institute de Montpellier
2011-2024
Centre Occitanie-Montpellier
2011-2024
Centre de Coopération Internationale en Recherche Agronomique pour le Développement
2011-2024
Université de Montpellier
2022-2024
Institut de Recherche pour le Développement
2022-2024
Institut Agro Montpellier
2022-2024
L'Institut Agro
2022-2024
American Society of Plant Biologists
2022-2023
Université de Tours
2021-2023
A major antiviral mechanism in plants is mediated by RNA silencing, which relies on the cleavage of viral dsRNA into virus-derived small interfering RNAs (vsiRNAs) DICER-like enzymes. Members Argonaute (AGO) family endonucleases then use these vsiRNA as guides to target RNA. This can result a phenomenon known recovery, whereby plant silences gene expression and recovers from symptoms. Endogenous mRNAs also be targeted vsiRNAs virus-induced silencing (VIGS). Although related other mechanisms,...
An important branch of plant immunity involves the recognition pathogens by nucleotide-binding, leucine-rich repeat (NB-LRR) proteins. However, signaling events downstream NB-LRR activation are poorly understood. We have analysed Arabidopsis translatome using ribosome affinity purification and RNA sequencing. Our results show that translational status hundreds transcripts is differentially affected upon protein RPM1, showing an overall pattern a switch away from growth-related activities to...
ABSTRACT Monoterpene indole alkaloids (MIAs) constitute a vast group of plant natural products synthesized within the Gentianales order. MIAs possess outstanding pharmacological properties that explain their wide use in treatment human diseases. These biological activities result from complex structure originate intricated biosynthetic pathways involving several enzyme families and notably cytochrome P450s. The early steps MIA synthesis involve P450s 71 clade, which catalyse conversion...
Summary The mTERF gene family encodes for nucleic acid binding proteins that are predicted to regulate organellar expression in eukaryotes. Despite the implication of this plant development and response abiotic stresses, a precise molecular function was assigned only handful number its c. 30 members plants. Using reverse genetics approach Arabidopsis thaliana combining biochemical techniques, we revealed new functions chloroplast protein, MDA1. We demonstrated MDA1 associates vivo with...
Plants interact with each other via a multitude of processes among which belowground communication facilitated by specialized metabolites plays an important but overlooked role. Until now, the exact targets, modes action, and resulting phenotypes that these induce in neighboring plants have remained largely unknown. Moreover, positive interactions driven release root exudates are prevalent both natural field conditions controlled laboratory environments. In particular, intraspecific suggest...
Plant NB-LRR proteins confer resistance to multiple pathogens, including viruses. Although the recognition of viruses by is highly specific, previous studies have suggested that activation results in a response targets all infected cell. Using an inducible system activate defenses, we find signaling does not result degradation viral transcripts, but rather prevents them from associating with ribosomes and translating their genetic material. This indicates defense against involves repression...
The mitochondrial transcription termination factor proteins are nuclear-encoded nucleic acid binders defined by degenerate tandem helical-repeats of ∼30 amino acids. They found in metazoans and plants where they localize organelles. In higher plants, the mTERF family comprises members several these have been linked to plant development response abiotic stress. However, knowledge molecular basis underlying physiological effects is scarce. We show that Arabidopsis mTERF9 protein promotes...
Pentatricopeptide repeat (PPR) proteins are helical repeat-proteins that bind RNA in a modular fashion with sequence-specificity can be manipulated by the use of an amino acid code. As such, PPR repeats promising scaffolds for design binding synthetic biology applications. However, vivo functional capabilities artificial built from consensus motifs just starting to explored. Here, we report functions protein, dPPRrbcL, made were designed sequence near 5' end rbcL transcripts Arabidopsis...
In both animals and plants, messenger (m)RNA export has been shown to contribute immune response regulation. The Arabidopsis nuclear protein MOS11, along with the nucleoporins MOS3/Nup96/SAR3 Nup160/SAR1 are components of mRNA machinery immunity mediated by nucleotide binding leucine-rich repeat receptors (NLR). human MOS11 ortholog CIP29 is part a small complex three additional members: RNA helicase DDX39, ALY, TAF15b. We systematically assessed biological roles homologs these proteins in...
Abstract Gene regulation at the transcriptional and translational level leads to diversity in phenotypes function organisms. Regulatory DNA or RNA sequence motifs adjacent gene coding act as binding sites for proteins that turn enable disable expression of gene. Whereas known range thousands, only a few have been examined. In this study, we predicted putative regulatory groups untranslated regions from genes regulated Arabidopsis thaliana under normal stressed conditions. The test group...
Vinca minor, also known as the lesser periwinkle, is a well-known species from Apocynaceae, native to central and southern Europe. This plant synthesizes monoterpene indole alkaloids, which are class of specialized metabolites displaying wide range bioactive- pharmacologically important properties. Within almost 50 alkaloids it produces, V. minor mainly accumulates vincamine, commercially used nootropic. Using combination Oxford Nanopore Technologies long read- Illumina short-read...
The organization of the genome into transcriptionally active and inactive chromatin domains requires well-delineated boundaries insulator functions in order to maintain identity adjacent genomic loci with antagonistic marks functionality. In plants that lack known insulators, mechanisms prevent heterochromatin spreading euchromatin remain be identified. Here, we show DNA Topoisomerase VI participates a boundary function safeguards expression genes islands within silenced regions. While some...
<title>Abstract</title> Identifying the genetic determinants underlying plant-plant interactions is key for understanding plant community dynamics, both in natural and agronomical systems. This report unveils complex architecture of interaction effects on aerial biomass septoria tritici blotch severity varietal mixtures wheat, using co-genome-wide association study. Fifty-four significant allelic between distinct loci were identified, with half involving hub loci. Some inter-individual...
Abstract The organization of the genome into transcriptionally active and inactive chromatin domains requires well-delineated boundaries insulator functions in order to maintain identity adjacent genomic loci with antagonistic marks functionality. In plants that lack known insulators, mechanisms prevent heterochromatin spreading euchromatin remain be identified. Here, we show DNA Topoisomerase VI participates a boundary function safeguards expression genes islands within silenced regions....
ABSTRACT The mitochondrial transcription termination factor proteins are nuclear-encoded nucleic acid binders defined by degenerate tandem helical-repeats of ~30 amino acids. They found in metazoans and plants where they localize to mitochondria or chloroplasts. In higher plants, the mTERF family comprises members several these have been linked plant development response abiotic stress. However, knowledge molecular basis underlying physiological effects is scarce. We show that Arabidopsis...