A5084270911- Surgical Simulation and Training
- Anatomy and Medical Technology
- Optical Imaging and Spectroscopy Techniques
- Photoacoustic and Ultrasonic Imaging
- Traumatic Brain Injury and Neurovascular Disturbances
- Augmented Reality Applications
- Stress Responses and Cortisol
- Meningioma and schwannoma management
- Intracerebral and Subarachnoid Hemorrhage Research
- Sleep and related disorders
- Maternal Mental Health During Pregnancy and Postpartum
- AI in cancer detection
- Tryptophan and brain disorders
- Neurosurgical Procedures and Complications
- Smart Systems and Machine Learning
- Birth, Development, and Health
- Digital Imaging in Medicine
- Simulation-Based Education in Healthcare
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Gestational Diabetes Research and Management
- Sleep and Wakefulness Research
- Gaze Tracking and Assistive Technology
- Prenatal Substance Exposure Effects
- Cerebrospinal fluid and hydrocephalus
- Ultrasound Imaging and Elastography
Kuopio University Hospital
2012-2024
National Hospital for Neurology and Neurosurgery
2024
University College London
2024
University of Eastern Finland
2012-2023
Eastern Finland Laboratory Center
2020-2021
A substantial proportion of patients undergoing surgery for chronic subdural hematoma (CSDH) use anticoagulation medication due to atrial fibrillation (AF). We assessed the risk postoperative thromboembolic and hemorrhagic complications in CSDH with a history AF their association outcome. This posthoc analysis nationwide multicenter randomized controlled trial conducted during 2020-2022 included preoperative AF. incidence associations functional outcomes mortality. Of 589 patients, 128...
Inflammatory mediators in both the peripheral circulation and central nervous system (CNS) are dysregulated major depressive disorder (MDD). Nevertheless, relatively little is known about role of T-helper (Th)-2 effector cytokines interleukin (IL)-5 IL-13 MDD. We examined serum levels these a Th-1 comparison cytokine, interferon (IFN)-γ, 116 individuals (MDD, n = 58; controls, 58). In our basic multivariate model controlling for effects potential confounders on associations between MDD...
Idiopathic intracranial hypertension (IIH) is aetiologically unknown disorder that associates with endocrinological disturbances, including dysfunction of hypothalamic-pituitary-adrenal-axis. Neuroendocrinological dysfunctions have also been characterized in psychiatric disorders, and therefore we investigated the presence disorders patients IIH a well-defined cohort. A total 51 were included. Patient demographics, symptoms, imaging data, ophthalmological clinical findings collected. At time...
A Finnish joint research effort Kuopio Birth Cohort (KuBiCo) seeks to evaluate the effects of genetics, epigenetics and different risk factors (medication, nutrition, lifestyle environmental aspects) during pregnancy on somatic psychological health status mother child.KuBiCo will ultimately include information 10,000 mother-child pairs who have given their informed consent participate in this cohort. Identification foetal that can potentially later manifest as disease requires a repository...
Pupillary responses have been for long linked to cognitive workload in numerous tasks. In this work, we investigate the role of pupil dilations context microsurgical training, handling microinstruments and suturing act particular. With an eye-tracker embedded on surgical microscope oculars, eleven medical participants repeated 12 sutures artificial skin under high magnification. A detailed analysis pupillary suture segments revealed that indeed varied not only according main but also...
Abstract Purpose Consumer-grade virtual reality (VR) has recently enabled various medical applications, but more evidence supporting their validity is needed. We investigated the accuracy of simulated surgical planning in a VR environment with temporal bones and compared it to conventional cross-sectional image viewing picture archiving communication system (PACS) interface. Methods Five experienced otologic surgeons measured significant anatomic structures fiducials on five fresh-frozen...
Shunt-dependent hydrocephalus after aneurysmal subarachnoid hemorrhage (aSAH) is a common sequelae leading to poorer neurological outcomes and predisposing various complications.A total of 2191 consecutive patients with aSAH were acutely admitted the Neurointensive Care at Kuopio University Hospital between 1990 2018 from defined population. A 349 (16%) received ventriculoperitoneal shunt, 101 an adjustable valve (2012-2018), 232 fixed pressure (1990-2011), 16 valveless shunt (2010-2013)....
Abstract Purpose There is only limited data on the application of virtual reality (VR) for evaluation temporal bone anatomy. The aim present study was to compare VR environment traditional cross-sectional viewing computed tomography images in a simulated preoperative planning setting novice and expert surgeons. Methods A ( n = 5) an group 5), based their otosurgery experience, were created. participants asked identify 24 anatomical landmarks, perform 11 distance measurements between...
Background. Evaluation of microsurgical proficiency is conventionally subjective, time consuming, and unreliable. Eye movement–based metrics have been promising not only in detection surgical expertise but also identifying actual cognitive stress workload. We investigated if pupil dilations blinks could be utilized parallel to accurately classify its moderating features, especially task-related stress. Methods. Participants (n = 11) were divided into groups based on prior experience...
Hyperspectral imaging (HSI) can enhance the recognition of normal and pathological tissues exposed during microscopic or endoscopic surgeries. However, robust HSI classification models would require meticulous documentation tissue-specific optical properties to account for individual variation intraoperative factors. Publicly available databases are yet scarce lack relevant metadata, anatomical accuracy, patients' characteristics which limits clinical utility data. The essential problem is...
In video-based training, clinicians practice and advance their skills on surgeries performed by colleagues themselves. Although microsurgeries are recorded daily, training centers lacking the workforce to manually annotate segments important for practitioners, such as instrument presence position. this work, we propose intelligent detection using Convolutional Neural Network (CNN) augment microsurgical training. The network was trained real videos which human annotators gathered a large...
Clinical studies have demonstrated that circulating cytokine profiles may differ between alexithymic and non-alexithymic subjects. We examined whether the levels of adiponectin (μg/ml) resistin (ng/ml) are independently related to features in a population-based sample.In 2005, clinical data including laboratory assessments were obtained from sub-sample (n = 308) Kuopio Depression Study general population study subjects aged 25-64 years. Based on Toronto Alexithymia Scale score 1998, 1999,...
Microsurgical techniques require highly skilled manual handling of specialized surgical instruments. Surgical process models are central for objective evaluation these skills, enabling data-driven solutions that can improve intraoperative efficiency.We built a model, defined at movement level in terms elementary actions ([Formula: see text]) and targets text]). The model also included nonproductive movements, which enabled us to evaluate suturing efficiency bi-manual dexterity. activities...
Introduction: In recent decades, the lack of educational resources for cadaveric dissections has complicated hands-on otological surgical training otorhinolaryngology residents due to poor availability cadaver temporal bones, facilities, and limited hours practice. Since students must gain adequate patient-safe skills, novel methods need be considered. this proof-of-concept study, a new virtual reality (VR) software is described; was used during national bone dissection course where we...
: 5-aminolevulinic acid (5-ALA) – precursor of protoporphyrin IX (PpIX) is utilized in fluorescence guided surgery (FGS) high-grade gliomas. PpIX used to identify traces glioma during resection. Visual inspection the seems inaccurate comparison optic techniques such as hyperspectral imaging (HSI). To characterize limits detection (i) visual evaluation and (ii) HSI analysis (iii) develop a classification system for visible non-visible fluorescence. Samples with increasing concentrations (C)...
Eye-hand coordination is a central skill in microsurgery. To develop efficacious microsurgical training environments to support development of eye-hand coordination, it important understand the workload associated with visuo-motor tasks We embedded an eye-tracker surgical microscope and collected eye-blink data 10 participants during microsuture task. Blink-rate was shown drop low levels compared resting-state rate be sensitive phases suture. discuss these findings light operator environments.
Distinct tissue types are differentiated based on the surgeon's knowledge and subjective visible information, typically assisted with white-light intraoperative imaging systems. Narrow-band (NBI) assists in identification enables automated classifiers, but many anatomical details moderate computational predictions cause bias. In particular, tissues' light-source-dependent optical characteristics, location, potentially hazardous microstructural changes such as peeling have been overlooked...