A5016705149- Traumatic Brain Injury and Neurovascular Disturbances
- Neurosurgical Procedures and Complications
- Trauma and Emergency Care Studies
- Traumatic Brain Injury Research
- Spinal Fractures and Fixation Techniques
- Hip and Femur Fractures
- S100 Proteins and Annexins
- Cardiac Arrest and Resuscitation
- Intracerebral and Subarachnoid Hemorrhage Research
- Radiation Dose and Imaging
- Acute Ischemic Stroke Management
- Pelvic and Acetabular Injuries
- Craniofacial Disorders and Treatments
- Dental Implant Techniques and Outcomes
- Obstructive Sleep Apnea Research
- Facial Trauma and Fracture Management
- Diabetic Foot Ulcer Assessment and Management
- CNS Lymphoma Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Frailty in Older Adults
- Nutrition and Health in Aging
- Cerebral Venous Sinus Thrombosis
- Cerebrospinal fluid and hydrocephalus
- MRI in cancer diagnosis
- Advanced MRI Techniques and Applications
University of Oulu
2018-2025
Oulu University Hospital
2018-2025
Helsinki University Hospital
2025
University of Helsinki
2025
Addenbrooke's Hospital
2024
University of Cambridge
2023-2024
Cambridge University Hospitals NHS Foundation Trust
2024
A substantial proportion of patients undergoing surgery for chronic subdural hematoma (CSDH) use anticoagulation medication due to atrial fibrillation (AF). We assessed the risk postoperative thromboembolic and hemorrhagic complications in CSDH with a history AF their association outcome. This posthoc analysis nationwide multicenter randomized controlled trial conducted during 2020-2022 included preoperative AF. incidence associations functional outcomes mortality. Of 589 patients, 128...
Muscle mass has been traditionally assessed by measuring paraspinal muscle areas at the level of third lumbar vertebra on computed tomography (CT). Neurological or neurosurgical patients seldom undergo CT scans region. Instead, temporal thickness (TMT), cross-sectional area (TMA) and radiodensity measured from head are readily available measures quality in these patient cohorts. The purpose this retrospective study was to establish CT-based reference values for TMT, TMA each decade age 0 100...
OBJECTIVE Craniectomy is a common neurosurgical procedure that reduces intracranial pressure, but survival necessitates cranioplasty at later stage, after recovery from the primary insult. Complications such as infection and resorption of autologous bone flap are common. The risk factors for complications subsequent removal unclear. aim this multicenter, retrospective study was to evaluate affecting outcome cranioplasty, with special emphasis on resorption. METHODS authors identified all...
Abstract Background Chronic subdural haematoma (CSDH) drainage is a common neurosurgical procedure. CSDHs cause excess mortality, which exacerbated by frailty. Sarcopenia contributes to frailty – its key component, low muscle mass, can be assessed using cross‐sectional imaging. We aimed examine the prognostic role of temporal thickness (TMT) measured from preoperative computed tomography head scans among patients undergoing surgical CSDH drainage. Methods retrospectively identified all who...
OBJECTIVE Autologous bone cranioplasty after decompressive craniectomy entails a notable burden of difficult postoperative complications, such as infection and flap resorption (BFR), leading to mechanical failure. The prevalence significance asymptomatic BFR is currently unclear. aim this study was radiologically monitor the long-term survival quality change in patients undergoing autologous cranioplasty. METHODS authors identified all 45 who underwent at Oulu University Hospital, Finland,...
OBJECTIVE The aim of this study was to compare the outcomes early (≤ 90 days) and delayed (> cranioplasty following decompressive craniectomy (DC) in patients with traumatic brain injury (TBI). METHODS authors analyzed participants enrolled Collaborative European NeuroTrauma Effectiveness Research Traumatic Brain Injury (CENTER-TBI) Neurotraumatology Quality Registry (Net-QuRe) studies who were diagnosed TBI underwent DC subsequent cranioplasty. These prospective, multicenter,...
Bone flap resorption (BFR) is the most prevalent complication resulting in autologous cranioplasty failure, but no consensus on definition of BFR or between radiological signs and relevance has been established. We set out to develop an easy-to-use scoring system intended standardize interpretation findings. All 45 patients operated at Oulu University Hospital from 2004 2014 were identified, bone status all available was evaluated using new system. Derived previous literature, a...
BACKGROUND AND OBJECTIVES: Global disparity exists in the demographics, pathology, management, and outcomes of surgically treated traumatic brain injury (TBI). However, factors underlying these differences, including intervention effectiveness, remain unclear. Establishing a more accurate global picture burden TBI represents challenging task requiring systematic ongoing data collection patients with across all management modalities. The objective this study was to establish registry that...
Autologous bone has been the gold standard of cranioplasty materials for decades. Unique to autologous cranioplasty, flap resorption is a poorly understood and unclearly defined complication. Even further, it unclear, whether process eventually stabilizes over time. Thus, sufficient follow-up period after unknown. The Oulu Resorption Score (ORS) straight-forward classification system radiological interpretation resorption. aims present study were evaluate reliability ORS using intra-class...
Primary central nervous system lymphoma (PCNSL) is an aggressive brain disease where lymphocytes invade along perivascular spaces of arteries and veins. The invasion markedly changes (peri)vascular structures but its effect on physiological pulsations has not been previously studied. Using magnetic resonance encephalography (MREGBOLD ) scanning, this study aims to quantify the extent which PCNSL involvement alters stability mediated by cerebral vasculature. Clinical implications relevance...
The epidemiology of traumatic brain injury (TBI) is unclear - it estimated to affect 27-69 million individuals yearly with the bulk TBI burden in low-to-middle income countries (LMICs). Research has highlighted significant between-hospital variability outcomes following emergency surgery, but overall incidence and remains unclear. To address this need, we established Global Epidemiology Outcomes Traumatic Brain Injury (GEO-TBI) registry, enabling recording all cases requiring admission...
Introduction Endoscopic third ventriculostomy (ETV) is becoming an increasingly widespread treatment for hydrocephalus, but research primarily based on paediatric populations. In 2009, Kulkarni et al created the ETV Success score to predict outcome of in children. The purpose this study create a prognostic model success adult patients with hydrocephalus. ability who will benefit from allow better primary patient selection both and shunting. This would reduce additional second procedures due...
<ns3:p>Background The epidemiology of traumatic brain injury (TBI) is unclear – it estimated to affect 27–69 million individuals yearly with the bulk TBI burden in low-to-middle income countries (LMICs). Research has highlighted significant between-hospital variability outcomes following emergency surgery, but overall incidence and remains unclear. To address this need, we established Global Epidemiology Outcomes Traumatic Brain Injury (GEO-TBI) registry, enabling recording all cases...
Decompressive craniectomy (DC) is an effective treatment of intracranial hypertension. Correspondingly, the procedure increasingly utilised worldwide. The number patients rendered vegetative following surgery has been a concern-a matter especially important in children, due to long anticipated lifetime. Here, we report long-term outcomes all paediatric DC from 11-year period tertiary-level centre that geographically serves half Finland.We identified younger than 18 years who underwent Oulu...
Commercial intrathecal baclofen treatment (ITBT) infusion pumps are recommended to be refilled within a maximum of 180 days, thus necessitating at least twice-yearly outpatient visits and refill injections. In particular, with 40-mL reservoir volumes would allow much longer intervals. We investigated stability in active implanted ITBT vivo intervals up 367 days study the feasibility lengthening beyond six months.We obtained 25 samples from 19 patients receiving varying pump All had system...