A5053291734- Cardiac Valve Diseases and Treatments
- Coronary Interventions and Diagnostics
- Infective Endocarditis Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Cardiac Structural Anomalies and Repair
- Cardiovascular Function and Risk Factors
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac pacing and defibrillation studies
- Acute Myocardial Infarction Research
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cerebrovascular and Carotid Artery Diseases
- COVID-19 and healthcare impacts
- Pulmonary Hypertension Research and Treatments
- Mechanical Circulatory Support Devices
- Advanced MRI Techniques and Applications
- Healthcare cost, quality, practices
- Aortic Disease and Treatment Approaches
- Antimicrobial Resistance in Staphylococcus
- Emergency and Acute Care Studies
- Ultrasound and Hyperthermia Applications
- Cardiac, Anesthesia and Surgical Outcomes
- Viral Infections and Vectors
- Liver Disease and Transplantation
- Central Venous Catheters and Hemodialysis
Universität Ulm
2015-2025
University Hospital Ulm
2016-2025
Schwarzwald-Baar Klinikum
2015
Klinikum Coburg
2015
Klinikum Fürth
2015
The aim of this study was to evaluate the outcome transcatheter mitral valve repair (TMVr) in patients with cardiogenic shock and significant regurgitation (MR). Patients severe MR have a poor prognosis setting conventional medical therapy. Because its favorable safety profile, TMVr is being increasingly used as an acute therapy population, though efficacy remains unknown. A multicenter, collaborative, patient-level analysis conducted. moderate (3+) or (4+) who were not surgical candidates...
<h3>Background</h3> Percutaneous coronary intervention with stent implantation is limited by the occurrence of re-stenosis and risk thromboses. <h3>Objective</h3> To define impact paclitaxel-coated balloon angioplasty plus endothelial progenitor cell capturing (EPC) in de novo artery disease. This combination may reduce neointimal proliferation within EPC address thrombosis facilitating rapid endothelialisation. <h3>Methods</h3> In this prospective single-blind multicentre randomised trial,...
Paclitaxel-coated balloons (PCBs) are a preferred treatment option for coronary in-stent restenosis. To date, data from randomized trials of alternative drug coatings lacking. The aim the Malaysian and German-Swiss was to investigate novel sirolimus-coated balloon (SCB) compared with PCB in restenosis.One hundred one patients drug-eluting stent restenosis were enrolled 2 identical comparing SCB (SeQuent SCB, 4 μg/mm²) clinically proven Please, 3 μg/mm²). Primary end point angiographic late...
Bioresorbable vascular scaffolds (BVS) have been available on the European market since November 2011. The ASSURE registry aims to investigate safety and efficacy of Absorb everolimus-eluting bioresorbable scaffold in a real-world setting.Patients with de novo coronary artery disease were consecutively enrolled at six German centres this prospective registry. Outcomes procedural success, cardiovascular death, myocardial infarction, ischaemia-driven target lesion revascularisation (TLR)....
Abstract Aims The coronavirus SARS-CoV-2 outbreak led to the most recent pandemic of twenty-first century. To contain spread virus, many nations introduced a public lockdown. How itself and measures social restriction affect hospital admissions due acute cardiac events has rarely been evaluated yet. Methods Results German authorities announced between March 21st April 20th, 2020. During this period, all patients suffering from an event admitted our ( N = 94) were assessed incidence rate...
Drug-coated balloons (DCBs) are an established treatment strategy for coronary artery disease. Randomized data on the application of DCBs in patients with acute syndrome (ACS) limited. We evaluated impact clinical presentation (ACS versus chronic syndrome) outcomes undergoing DCB or drug-eluting stent (DES) a prespecified analysis BASKET-SMALL 2 trial (Basel Kosten Effektivitäts Trial-Drug-Coated Balloons Versus Drug-Eluting Stents Small Vessel Interventions).BASKET-SMALL randomized 758...
Introduction Despite growing evidence for sex-specific differences in cardiovascular disease, sex is poorly considered the management of infectious endocarditis (IE). Purpose This study aimed to assess aspects diagnosing IE. Methods All consecutive patients admitted at Ulm University Heart Center with suspected IE between 2009 and 2019 were included. was diagnosed using Duke criteria. Risk factors, clinical presentation in-hospital outcomes along impact diagnostic delay compared male female...
Since its introduction in 2003, Abbott's MitraClip (MC) has become the most established catheter-based treatment for mitral regurgitation (MR). Recent approval of Edwards Lifescience's PASCAL device extended field TEER. The aim this retrospective multicenter study was to compare and MC regarding procedural results short- long-term outcomes after valve transcatheter edge-to-edge repair (TEER). Data from 3 high-volume centers were analyzed. primary endpoint residual MR at discharge. Secondary...
The development of transcatheter tricuspid edge-to-edge repair for regurgitation is a therapeutic milestone but specific periprocedural risk assessment tool lacking. TRI-SCORE has recently been introduced as dedicated score valve surgery.This study analyzes the predictive performance following repair.180 patients who underwent at Ulm University Hospital were consecutively included and stratified into three groups. was assessed throughout follow-up period 30 days up to 1 year.All had severe...
Cases of thromboembolic events in 2021 flared up the discussion about safety Astra Zeneca's AZD1222 vaccine. We hereby report three cases pulmonary embolism (PE), one case extended portal vein thrombosis, and combined thrombosis PE within 2 weeks after vaccination with Zeneca vaccine a 60-year-old, 50-year old, 33-year-old, 30-year 40-year-old male that year. All patients were healthy before. In patients, we observed thrombocytopenia to some extent unusually low antibody levels for Spike...
Pulse transit time (PTT) is generally assumed to be a surrogate marker for blood pressure changes and arterial stiffness. The aim was evaluate whether pulmonary PTT (pPTT) may noninvasively measured by Doppler echocardiography it might valuable detecting hemodynamic vascular alterations.We defined pPTT as the interval between R-wave in ECG corresponding peak late systolic vein flow velocity pw-Doppler vein. Twelve consecutive patients with hypertension (PH) 12 subjects without any...
CENTURY II is a prospective, multicentre, randomised, single-blind trial comparing the bioresorbable polymer sirolimus-eluting Ultimaster® stent (BP-SES) with permanent everolimus-eluting XIENCE (PP-EES). Here we present pre-specified analysis of safety and efficacy outcomes in subgroup patients small vessel coronary artery disease.CENTURY included 525 lesions reference diameter ≤2.5 mm. Treatment was randomly assigned: 277 received BP-SES (399 lesions) 248 PP-EES (377 lesions). The primary...
Background Evidence regarding favorable treatment of patients with functional mitral regurgitation (FMR) using transcatheter edge-to-edge repair (TEER) is constantly growing. However, there only few data directly comparing TEER and surgical valve (SMVr). Aims To compare baseline characteristics, short-term 1-year outcomes in FMR undergoing (MV) or SMVr a meta-analytic approach. Methods Systematic database search identified 1,703 studies reporting on for between January 2010 December 2020. A...
Background: Atrial fibrillation is common in patients with mitral regurgitation (MR) and has a negative impact on the clinical outcome of valvular heart disease. We aimed to evaluate pre-procedural atrial long-term outcomes MR undergoing transcatheter valve repair by MitraClip implantation. Methods: analysed 355 consecutive without symptomatic, severe inoperability or high surgical risk implantation three-year follow-up. Results: In implantation, we found advanced age, higher baseline...