A5100384281- Pediatric Urology and Nephrology Studies
- Kidney Stones and Urolithiasis Treatments
- Cardiac tumors and thrombi
- Sarcoma Diagnosis and Treatment
- Renal cell carcinoma treatment
- Pelvic floor disorders treatments
- Aortic Disease and Treatment Approaches
- Urological Disorders and Treatments
- Vascular Tumors and Angiosarcomas
- Aortic aneurysm repair treatments
- Intraocular Surgery and Lenses
- Streptococcal Infections and Treatments
- Malaria Research and Control
- Renal and related cancers
- Urinary Bladder and Prostate Research
- Bone Tumor Diagnosis and Treatments
- Foot and Ankle Surgery
- Pharmacological Effects of Natural Compounds
- Pregnancy-related medical research
- Bladder and Urothelial Cancer Treatments
- Telemedicine and Telehealth Implementation
- Tracheal and airway disorders
- Lower Extremity Biomechanics and Pathologies
- Infectious Aortic and Vascular Conditions
- Traumatic Ocular and Foreign Body Injuries
Tongji Hospital
2014-2025
Huazhong University of Science and Technology
2014-2025
Renmin Hospital of Wuhan University
2016-2025
Wuhan University
2016-2025
Nanjing Drum Tower Hospital
2020-2023
Peking University
2020-2022
Peking University Third Hospital
2020-2022
Sun Yat-sen University
2018-2022
Sun Yat-sen Memorial Hospital
2018-2022
Peking University First Hospital
2022
Necrotizing fasciitis (NF), a life-threatening soft tissue infection, requires early diagnosis, prompt and repeated surgical intervention, broad-spectrum antibiotic therapy. The aim of this study was to identify the independent predictors mortality among patients with NF in Taiwan.We retrospectively reviewed medical records all who were admitted Chi-Mei Medical Center, Tainan, Taiwan, diagnosis NF. definitive confirmed by findings, including (1) dishwater or foul-smelling discharge, (2)...
Depression presents sexual dimorphism, and one important factor that increases the frequency of depression contributes to sex-specific variations in its presentation is obesity. The conventional use Body Mass Index (BMI) as an indicator obesity inherently limited due inability distinguish between fat lean mass, which limits predictive utility for risk. Implementation dual-energy X-ray absorptiometry (DXA) investigated associations body composition (fat appendicular mass) depression. Data...
The pathogenesis of stress urinary incontinence (SUI), a condition common in women, remains to be fully elucidated. This study revealed that the incidence SUI is associated with mitochondrial homeostasis dysregulation following oxidative fibrous connective tissue pelvic floor. SIRT1 an essential factor for maintaining homeostasis; however, its potential role and mechanism action remain unclear. Both vitro vivo, we observed reduced expression inhibit PGC-1α/NRF1/TFAM PINK1/Parkin signalling...
Principal malaria vectors in Africa, An. gambiae and coluzzii, share an inversion polymorphism on the left arm of chromosome 2 (2La/2L+a) that is distributed non-randomly environment. Genomic sequencing studies support role strong natural selection maintaining steep clines 2La frequency along environmental gradients aridity, physiological have directly implicated heat desiccation tolerance, but precise genetic basis underlying behavioral mechanisms remain unknown. As insect cuticle primary...
The regulation of the extracellular matrix (ECM) by mechanical stress is interest as ECM essential in development pelvic organ prolapse. In present study, effect overexposure to on ECM, and probable underlying mechanisms cultured human uterosacral ligament fibroblasts (hUSLFs), was explored. Mechanical has an oxidation‑antioxidation products parametrial fibroblasts. Thus, hUSLFs were incubated with different concentrations hydrogen peroxide elucidate any potential interactions. Excess H2O2...
Streptococcus suis serotype 2 (SS2), a major swine pathogen and an emerging zoonotic agent, has greatly challenged global public health. The encoding proteins with unknown functions the bacterium encodes are obstruction to studies of pathogenesis. A novel surface protective antigen HP0197 is one these which have no sequence homology any known protein. In present study, protein was determined be involved in bacterial virulence through evaluation isogenic mutant (Δhp0197) both mice pigs....
Artemisinin (ART) is an efficacious and safe anti-malarial drugs but has low oral bioavailability auto-induction profiles during multiple dosing. The pharmacokinetic disadvantages have been found to partially depend on the induction of cytochrome P-450 enzymes by ART resulted in therapeutic failure due insufficient drug levels. present study, therefore, investigated impacts chrysosplenetin (CHR), a polymethoxylated flavonoid from Artemisia annua, pharmacokinetics efficacy against Plasmodium...
Abstract Background To compare the safety and efficacy of retrograde intrarenal surgery (RIRS) modified Ultra-mini percutaneous nephrolithotomy (UMP) in semi-supine combined lithotomy position for management 1.5–3.5 cm lower pole renal stones (LPSs). Methods A total 63 patients with LPSs who underwent RIRS ( n = 33) or UMP 30) diameter between January 2017 2019 were analyzed retrospectively. Modified was performed a 9.5/11.5 F ureteral access sheath (UAS) inserted during procedure order to...
Meibomian gland dysfunction (MGD) has become a prevalent ocular surface disorder. Its pathogenesis is regarded as self-perpetuating inflammatory vicious circle. Intense Pulsed Light (IPL) treatment was recently applied to improve the meibomian function and reduce symptoms of MGD. However, studies investigating change specific cytokines during IPL remained sparse. To further figure out how modulates in tears MGD, we therefore performed cross-sectional study enrolled 32 patients from March...
Abstract Background The efficacy of Djulis for skin care is currently based on cellular or animal models, and the clinical aspect not in place. Aim This study to investigate synergistic effect fish collagen ( Chenopodium formosanum Koidz.) improvement parameters. We used combination hydrolyzed develop a new functional formula improvement. Patients/Methods Fifty volunteers were randomly allocated (in 1:1 ratio) placebo drink group. Volunteers required consume 50 mL daily 8 weeks. For...
PurposeTo characterize type A aortic dissection (TAAD) in the Chinese population using high-resolution computed tomography (CT) and explore potential candidacy for endovascular repair of TAAD. MethodsThe imaging studies medical records all 302 patients presenting with TAAD at two hospitals from 2010 to 2013 were reviewed. Of these, 221 excluded because missing/inadequate preoperative CT scans. The remaining 91 (64 men; mean age 51.1±7.5 years) had data adequate assess anatomical suitability...
To assess the effects of using Chinese herbs in assisted reproductive technology. Four hundred and thirty-three subjects aged less than 42 years with infertility due to Fallopian tube or male-related factors who were willing undertake vitro fertilization embryo transplantation randomly allocated a herb intervention group (n=216) conventional treatment control (n=217). All received one four routine ultra-ovulation-promoting therapies at Reproductive Center Third Hospital Affiliated Beijing...
A novel semirigid ureterorenoscope, named the Sotn was designed with a vacuum suction system. The present study aimed to evaluate feasibility and safety of using ureterorenoscope manage single proximal ureteral or renal pelvic stones.Data were retrospectively collected from consecutive patients treated between February 2010 August 2015 at Sun Yat-sen Memorial Hospital University Jiangmen Wuyi Traditional Chinese Medicine in China. primary outcome stone-free rate (SFR) 1 month. secondary...
Objective Previous studies have questioned the safety and efficacy of minor salivary gland biopsy in diagnosis Sjögren’s syndrome, citing complications difficulty pathologic evaluation. This study aims to determine rate specimen adequacy risk after biopsy. Study Design Case series. Setting Single tertiary care center. Methods We reviewed records all patients who underwent at our institution from October 1, 2016, September 2021. Demographics, comorbidities, symptoms, serologic results were...
Fenestrated or branched endovascular aortic arch repair (fb-arch repair) is an effective option for treating complex lesions, including thoracic aneurysms and dissections. However, the relatively high rate of re-intervention due to target vessel (TV)-related endoleaks have raised concerns. This study aimed determine risk factors TV-related after fb-arch repair. was a retrospective analysis all patients undergoing between 2017 2021in nanjing drum tower hospital China. All underwent computed...
Objective: Parasagittal meningiomas (PSM) may pose a difficult surgical challenge because venous patency and collateral anastomoses have to be clearly defined for correct planning. The aim of this study was the diagnostic accuracy computed tomography venography (CTV) in assessing superior sagittal sinus (SSS) obstruction collaterals. Methods: Twenty-four patients undergoing surgery located adjacent SSS were prospectively evaluated. All underwent both conventional examination CTV. Computed...
In this study, we used a self-contrast method, which excluded the individual difference, to evaluate inhibitory effect of chrysosplentin (CHR) in presence or absence artemisinin (ART) on P-glycoprotein (P-gp) transport activity. A sensitive and rapid UHPLC-MS/MS method was applied for quantification digoxin, P-gp-specific substrate, rat plasma. pharmacokinetic study carried out: first after an oral administration digoxin at dose 0.09 mg/kg (first period), followed by 20-day wash-out, then...
To explore the establishment of a scoring system that can provide reference for clinical decision making regarding endoscopic treatment 1-2 cm lower pole stones (LPS).The data patients with renal calculi who were treated percutaneous nephrolithotomy (PCNL) or retrograde intrarenal surgery (RIRS) in three hospitals from January 2013 to December 2017 analyzed retrospectively. Multivariable logistic analysis was performed determine statistically significant indicators and regression...