- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Stroke Rehabilitation and Recovery
- Obstructive Sleep Apnea Research
- Cardiovascular and Diving-Related Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Venous Thromboembolism Diagnosis and Management
- Sleep and Wakefulness Research
- Intracerebral and Subarachnoid Hemorrhage Research
- Neuroscience of respiration and sleep
- Peripheral Artery Disease Management
- Cerebral Venous Sinus Thrombosis
- Sleep and related disorders
- Trypanosoma species research and implications
- Vestibular and auditory disorders
- Cardiovascular Health and Disease Prevention
- Intracranial Aneurysms: Treatment and Complications
- Advanced Neuroimaging Techniques and Applications
- Functional Brain Connectivity Studies
- Cerebrospinal fluid and hydrocephalus
- Healthcare Systems and Public Health
- Cerebral Palsy and Movement Disorders
- Cannabis and Cannabinoid Research
- Dysphagia Assessment and Management
- Coenzyme Q10 studies and effects
Universidade de Ribeirão Preto
2012-2025
Universidade de São Paulo
2015-2025
Instituto de Neurociências e Comportamento
2022-2025
São Camilo Hospital
2023
University of Lausanne
2023
Clinics Hospital of Ribeirão Preto
2014-2022
University of Bern
2018-2019
Institute of Social and Preventive Medicine
2018-2019
Federal Almazov North-West Medical Research Centre
2019
National Cerebral and Cardiovascular Center
2018
What is known and objective Cannabidiol (CBD) the main non-psychotropic component of Cannabis sativa plant. REM sleep behaviour disorder (RBD) a parasomnia characterized by loss muscle atonia during associated with nightmares active dreaming. We have described effects CBD in RBD symptoms patients Parkinson's disease. Cases summary Four treated had prompt substantial reduction frequency RBD-related events without side effects. new conclusion This case series indicates that able to control RBD.
<b><i>Background:</i></b> The modified Rankin Scale (mRS) is a commonly used scale to assess the functional outcome after stroke. Several studies on mRS showed good reliability, feasibility, and interrater agreement of this using face-to-face assessment. However, telephone assessment more time-efficient way obtain an grade than interview. aim study was validate among Portuguese structured interview in sample Brazilian stroke patients....
The Guidelines for Stroke Rehabilitation are the result of a joint effort by Scientific Department Neurological Brazilian Academy Neurology aiming to guide professionals involved in rehabilitation process reduce functional disability and increase individual autonomy. Members group participated web discussion forums with predefined themes, followed videoconference meetings which issues were discussed, leading consensus. These guidelines, divided into two parts, focus on implications recent...
Background: Mechanical Thrombectomy (MT) treats Acute Ischemic Stroke (AIS) removing the thrombus, and improves clinical outcome. However, it uses high quantities of contrast, with risk Contrast Extravasation (CE), but also Hemorrhagic Transformation (HT), both detected by cranial Computed Tomography (CT). to differentiate between them, is necessary perform a control CT 72 hours after MT. Aims: This study aims develop tool capable differentiating HT from EC in CT. Methodology: 398 CTs were...
Introduction: Acute stroke care (ASC) is crucial to improve patient outcomes. In developing regions, optimizing resources essential enhance effectiveness of careline networks. Sao Paulo State presents a unique challenge due its territory and healthcare infrastructure. This study aims analyze current potential territorial coverage for expanding ASC. Hypothesis: We hypothesize that by systematically analyzing existing resources, mapping designing 30-60 minutes isochrones, it possible identify...
The data on predictors of poor outcomes for stroke patients in middle-income countries are lacking. To identify the acute phase after a first-ever (FES) outcome within 3 months and 1 year population-based study town Matão, state São Paulo, Brazil. We prospectively investigated characteristics with FES from prospective study, registry, 2015 to 2020. Poor was defined as modified Rankin scale (mRS) score 6, assessed at follow-up. association between analyzed by logistic regression analysis. Of...
Sleep disturbances are common in acute stroke patients and linked with a negative outcome. However, it is also unclear which how such changes may be related to To explore this link, we performed sleep electroencephalogram (EEG) study animals humans after ischemic stroke. (1) Animal study: 12 male rats were assigned two groups: ischemia (IS) sham surgery (Sham). In both groups, architecture was investigated 24 h before for the following 3 days. (2) Human 153 participating SAS-CARE...
<b><i>Background:</i></b> Basilar artery occlusion (BAO) is a rare stroke subtype with high mortality rates. Best BAO reperfusion strategy still controversial. <b><i>Objective:</i></b> We aim to describe outcomes of patients submitted mechanical thrombectomy (MT) in comprehensive center Brazil and analyze which previous published computed tomography angiography (CTA) collateral score better predict functional outcomes....
The optimal anesthetic management for endovascular therapy (EVT) in patients with posterior circulation stroke remains unclear. Our objective was to investigate the impact of early intubation enrolled BASICS trial (Basilar Artery International Cooperation Study).
OBJECTIVE: Obstructive sleep apnea is frequent during the acute phase of stroke, and it associated with poorer outcomes.A well-established relationship between supine obstructive severity exists in nonstroke patients.This study investigated frequency positional patients ischemic or hemorrhagic stroke.METHODS: Patients who suffered their first either hemorrhagic, were subjected to a full polysomnography, including continuous monitoring positions, night after symptom onset.Obstructive was...
Background: Given the importance of acute stroke care for public health in terms its burden and consequences like disability death, evidence-based practice has directed development clinical protocols operational guidelines to populations affected by this pathology.
 Aim: To evaluate impact implementing line Urgency Emergency Care Network a large Brazilian municipality.
 Methods: This is retrospective study, conducted between 2014 2019 services Ribeirao Preto, SP, municipality...
Scarce data are available on the occurrence of symptomatic intracranial hemorrhage related to intravenous thrombolysis for acute stroke in South America. We aimed address frequency and clinical predictors after at our tertiary emergency unit Brazil.We reviewed radiological 117 consecutive ischemic patients treated with hospital between May 2001 April 2010. compared results those Safe Implementation Thrombolysis Stroke registry. Univariate multiple regression analyses were performed identify...
<h3>Objective:</h3> To determine the rate of symptomatic intracranial hemorrhage (SIH) and in-hospital mortality among patients with acute ischemic stroke related to Chagas disease (CD) treated IV tissue plasminogen activator (TPA). <h3>Methods:</h3> In this retrospective cohort study, consecutive TPA routinely tested for CD were retrospectively selected from a single-center, hospital-based, prospective registry 2001 2012. Demographic clinical data obtained as well mortality. CT scans...
Background Assessment of the impact thrombectomy learning curve on clinical outcomes is essential for developing healthcare system protocols. Aims The aim this study was to assess effect case volume procedural and in a Brazilian registry. Methods A total 645 patients with acute ischemic stroke treated by were included analysis. Patients divided into two groups regarding period treatment: early group late group. Results In adjusted analysis, treatment an independent predictor recanalization...