A5005997325- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Lubricants and Their Additives
- Tribology and Wear Analysis
- Lung Cancer Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Herpesvirus Infections and Treatments
- Cancer Immunotherapy and Biomarkers
- Nutrition and Health in Aging
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Gear and Bearing Dynamics Analysis
- Cytomegalovirus and herpesvirus research
- Lung Cancer Treatments and Mutations
- Hepatitis B Virus Studies
- Immune cells in cancer
- Anesthesia and Pain Management
- Microbial Community Ecology and Physiology
- Soil Carbon and Nitrogen Dynamics
- Pleural and Pulmonary Diseases
- Soil and Water Nutrient Dynamics
- Cardiac, Anesthesia and Surgical Outcomes
- Immune Cell Function and Interaction
- Meningioma and schwannoma management
- PARP inhibition in cancer therapy
Second Affiliated Hospital of Zhejiang University
2016-2025
Xi’an University of Posts and Telecommunications
2024
Gansu Agricultural University
2017-2024
Chinese Academy of Forestry
2024
Jilin Agricultural University
2023
Peking University
2022
Shanghai University of Traditional Chinese Medicine
2022
Renmin Hospital of Wuhan University
2022
Fuzhou University
2022
Shuguang Hospital
2022
Rationale: Idiopathic pulmonary fibrosis (IPF) is an irreversible, fatal interstitial lung disease lacking specific therapeutics.Nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme of nicotinamide adenine dinucleotide (NAD) salvage biosynthesis pathway and a cytokine, has been previously reported as biomarker for diseases; however, role NAMPT in not elucidated.Methods: We identified level changes by analyzing public RNA-Seq databases, verified collected clinical samples...
The complement system plays a critical role in ischemia-reperfusion injury (IRI)-mediated delayed graft function (DGF). To better understand the roles of activation pathways IRI kidney transplantation, donor kidneys were treated ex vivo with terminal pathway (TP) inhibitor, anti-rat C5 mAb 18A10, or alternative (AP) inhibitor TT30 for 28 h at 4°C pretransplantation syngeneic transplantation rat model. All 18A10- and 67% TT30-pretreated grafts, but only 16.7% isotype control-pretreated...
The potential benefits of home enteral nutrition (HEN) and the effects HEN on quality life (QOL) after esophagectomy remain unclear. aim was to investigate effect 3 months health related QOL nutritional status esophageal cancer patients who were preoperatively malnourished.142 malnourished (PG-SGA stage B or C) with assigned receive Ivor Lewis minimally invasive (MIE group) laparoscopic jejunal feeding tube placement open (OE nasojejunal placement. After discharge, in MIE group received...
In resectable oesophageal squamous cell carcinoma (ESCC), the efficacy of camrelizumab combined with chemotherapy and apatinib followed by minimally invasive oesophagectomy is not clear. We aimed to fill this knowledge gap.
Thinning-a widely used forest management practice-can significantly influence soil nitrogen (N) cycling processes in subtropical forests. However, the effects of different thinning intensities on nitrification, denitrification, and their relationships with properties microbial communities remain poorly understood. Here, we conducted a study China applied three treatments, i.e., no (0 %), intermediate (10-15 heavy (20-25 investigated intensity potential nitrification rate (PNR),...
In the last decade, numerous microRNAs (miRNAs) have been identified in diverse virus families, particularly herpesviruses. Gallid alphaherpesvirus 2 (GaHV2) is a representative oncogenic that induces rapid-onset T-cell lymphomas its natural hosts, namely Marek’s disease (MD). GaHV2 genome there are 26 mature miRNAs derived from 14 precursors assembled into three clusters, Meq-cluster, Mid-cluster and LAT-cluster. Several miRNAs, especially those Meq-cluster (e.g. miR-M4-5p), demonstrated to...
Background Esophageal cancer (ESCA) is a form of malignant tumor associated with chronic inflammation and immune dysregulation. However, the specific status key mechanisms regulation in this disease require further exploration. Methods To investigate features human ESCA microenvironment its possible regulation, we performed mass cytometry by time flight, single-cell RNA sequencing, multicolor fluorescence staining tissue, flow analyses on paracancerous tissue from treatment-naïve patients....
Abstract Background To investigate the long-term efficacy of minimally invasive Ivor Lewis esophagectomy (MIILE) in esophageal squamous cell carcinoma (ESCC) patients, a retrospective comparison quality life (QOL) and survival between patients who underwent MIILE left transthoracic (Sweet approach) was conducted. Methods A detailed database search identified 614 243 Sweet January 2011 December 2017. After propensity score matching, 216 paired cases were selected for statistical analysis....
This work was to investigate the drug resistance, molecular and virulence characteristics of methicillin-resistant Staphylococcus aureus (MRSA) in burn patients provide empiric antibiotic therapy for clinical treatment. A total 365 non duplicate strains, including 85 MRSA 280 methicillin-susceptible (MSSA), were collected from 2008 2015. The susceptibility tests antibacterial agents performed by Kirby-Bauer disk diffusion method. Polymerase chain reaction (PCR) gel electrophoresis...
K-means clustering algorithm is one of the most popular technique for in machine learning, however, existing k-means algorithm, ability different features and importance data objects are treated equally; discriminative cannot be differentiated effectively. In light this limitation, paper put forward an enhanced regularized type with adaptive weights which we introduced feature matrix vector into objective function developed a new l2-norm regularization to features, then obtained...
The purpose of this retrospective study was to demonstrate the safety and feasibility three-port single-intercostal video-assisted thoracoscopic surgery (SIC-VATS) segmentectomy compared uniportal (UVATS) segmentectomy.We included 544 patients diagnosed with cT1N0M0 non-small-cell lung cancer (NSCLC) who underwent between January 2020 August 2021, including 147 397 SIC-VATS UVATS, respectively. After incorporating preoperative clinical variables, we surgical outcomes perioperative indicators...
Minimally invasive esophagectomy (MIE) Ivor Lewis has been increasingly performed over the last two decades. To guide implementation of this technically demanding procedure, a comprehensive assessment MIE-Ivor learning curves should include both general competence to accomplish procedure and ability generate oncological benefits. These objectives are believed be associated with different phases curve.A retrospective review first 109 patients who underwent by single qualified surgeon was...
Abstract Rationale: Pleuroperitoneal communication (PPC) has been reported to complicate continuous ambulatory peritoneal dialysis (CAPD). However, cases of patients in whom the results methylene blue dye test and peritoneopleural scintigraphy were negative treatment was thoracoscopic surgery have rarely reported. Patient concerns: A 58-year-old man with end-stage chronic renal failure who underwent CAPD presented massive right-sided hydrothorax. The pleural fluid glucose level high. Results...
In this retrospective study, we aimed to demonstrated that three-port single-intercostal (SIC) thoracoscopic lobectomy is an effective choice for lung cancer by comparing the perioperative outcomes of patients with non-small-cell treated SIC and conventional multiple-intercostal (MIC) lobectomy.From January 2013 2018, 642 underwent via a or MIC technique. Propensity-matched analysis incorporating preoperative clinical variables was used compare between two groups.The first 20 were excluded...
AbstractAbstractThis experiment was conducted to evaluate the growth performance, regulating factors, and liver morphology of chicks hatched from egg-laying breeding hens dietary supplemented with additives (β-carotene). Hy-line were allocated into three groups replicates/group. The treatments as follows: basal diet a control (Con), 120 (βc-L) or 240 (βc-H) mg/kg β-carotene diet. After 6 weeks, eggs collected incubated. fed same results showed that in βc-L group increased body weight at 21...
To investigate the safety and effectiveness of a double semipurse string suture method for jejunum fixation in laparoscopic needle catheter jejunostomy minimally invasive Ivor Lewis esophagectomy (MIILE).Two hundred six esophageal cancer patients continuously receiving MIILE from March 2014 to February 2018 were enrolled. In all patients, was applied jejunostomy. The methods details this technique are introduced herein. General information, clinical data, postoperative complications...
Abstract Marek’s disease virus (MDV) strain GX0101 was the first reported field of recombinant gallid herpesvirus type 2 (GaHV-2). However, splenic proteome MDV-infected chickens remains unclear. In this study, a total 28 1-day-old SPF were intraperitoneally injected with chicken embryo fibroblast (CEF) containing 2000 PFU GX0101. Additionally, control group, consisting four one-day-old chickens, received intraperitoneal equal doses CEF. Blood and various tissue samples collected at...