Qin L

ORCID: 0000-0002-1754-7083
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About
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Research Areas
  • Breast Implant and Reconstruction
  • Breast Cancer Treatment Studies
  • Environmental and Agricultural Sciences
  • Evaluation Methods in Various Fields
  • Liver Disease Diagnosis and Treatment
  • Ginseng Biological Effects and Applications
  • Cell Adhesion Molecules Research
  • Advanced Computational Techniques and Applications
  • BRCA gene mutations in cancer
  • Osteoarthritis Treatment and Mechanisms
  • Geomechanics and Mining Engineering
  • Healthcare and Venom Research
  • RNA Interference and Gene Delivery
  • Cancer-related molecular mechanisms research
  • Traditional Chinese Medicine Analysis
  • Structural Engineering and Vibration Analysis
  • Advanced Measurement and Detection Methods
  • Traditional Chinese Medicine Studies
  • Vibration and Dynamic Analysis
  • MicroRNA in disease regulation
  • Ideological and Political Education
  • Electromagnetic Launch and Propulsion Technology
  • Virus-based gene therapy research
  • Social Media in Health Education
  • Mechanical stress and fatigue analysis

Jiangsu Province Hospital
2025

Nanjing Foreign Language School
2025

Soochow University
2024-2025

First Affiliated Hospital of Soochow University
2024-2025

Nanjing Medical University
2025

Guizhou University
2025

Sun Yat-sen University
2025

New York University
2025

Wannan Medical College
2024

Beijing Information Science & Technology University
2024

Immune functions decline with aging, leading to increased susceptibility various diseases including tumors. Exploring aging-related molecular targets in elderly patients cancer is thus highly sought after. Here we find that an ER transmembrane enzyme, sterol O-acyltransferase 2 (SOAT2), overexpressed regulatory T (Treg) cells from lung squamous cell carcinoma (LSCC), while radiomics analysis of LSCC associates SOAT2 expression reduced immune infiltration and poor prognosis. Mechanically, ex...

10.1038/s41467-025-56002-w article EN cc-by-nc-nd Nature Communications 2025-01-13

Abstract A murine heterotopic, nonvascularized cardiac allograft model was used to examine the effects of immunosuppressive cytokine, viral IL-10 (vIL-10), delivered by gene transfer on graft rejection. Retroviral-mediated and expression vIL-10 significantly prolonged survival, without conventional systemic immunosuppression, from 12.1 +/- 0.8 days 39.4 2.5 (p < 0.0001). The effect specific, dose dependent, restricted site transplantation. PCR analysis demonstrated specific...

10.4049/jimmunol.156.6.2316 article EN The Journal of Immunology 1996-03-15

Indefinite graft survival was obtained with murine cardiac allografts using the combined administration of monoclonal antibodies (mAbs) directed against receptor ligand pair CD2-CD48. Although each antibody could prolong when given alone, neither resulted in indefinite seen combination. Combined mAb is associated inhibition T cell priming and help subsequent cytotoxic lymphocyte generation. This indicates that interaction between CD2 its important for antigen recognition, mAbs may prove to...

10.1084/jem.179.1.341 article EN The Journal of Experimental Medicine 1994-01-01

Since ancient times, social civilization has been advancing. As The Times change, each period its own development and the problems that come with it. Nowadays, world is in an era of advanced science technology rapid information dissemination. During this period, Internet became essential thing. And paper needs to analyze impact on society. Include positive influence negative different aspects. We-media a particularly iconic thing era. It contains variety strange content. Therefore, help...

10.54254/2754-1169/2024.ld19608 article EN cc-by Advances in Economics Management and Political Sciences 2025-01-03

The tilt angle of solar active regions (AR) is crucial for the Babcock-Leighton type dynamo models in buildup polar field. However, divergent results regarding properties angles were reported due to their wide scatter, caused by intrinsic mechanisms and measurement errors. Here, we mutually validate magnetogram-based AR dataset from Wang, Jiang, & Luo with Debrecen Photoheliographic Data identifying common data points where both datasets provide comparable same AR/sunspot. validated...

10.48550/arxiv.2502.11698 preprint EN arXiv (Cornell University) 2025-02-17

The preconditioned iterative integration-exponential method is an innovative regularization technique designed to solve ill-conditioned linear problems. However, the has been primarily applied symmetric positive definite problems, and a notable limitation its inability adaptively determine optimal number of iterations. To overcome this limitation, present study demonstrates that can also be effectively nonsymmetric systems. Furthermore, improved proposed by combining refinement algorithm...

10.25259/jksus_14_2024 article EN cc-by-nc-nd Journal of King Saud University - Science 2025-02-28

Vegetation increases surface roughness, reduces wind speeds and decreases sand carrying capacity, thereby effectively intercepting wind-sand flows promoting deposition. Exploring the distribution of sand-fixing plant sediment particles characteristics morphology parameters in desert-oasis transition zone can provide a certain theoretical foundation for regional ecological vegetation construction desertification control. In this paper, particle size sediments (0–2 cm) under cover five typical...

10.3389/fenvs.2025.1556083 article EN cc-by Frontiers in Environmental Science 2025-03-19

10.32604/cmc.2025.063358 article EN Computers, materials & continua/Computers, materials & continua (Print) 2025-01-01

Abstract Background Propofol, a widely administered sedative, is associated with potential hemodynamic instability during anaesthesia. Ciprofol introduces cyclopropyl group to the chemical structure of propofol, forming an R-shaped hand and characterised by rapid induction, recovery, good controllability high degree clinical safety. Methods This prospective randomised, double-blind, controlled trial aimed assess effects ciprofol on haemodynamics its safety efficacy under general anaesthesia...

10.1186/s12871-025-03054-6 article EN cc-by BMC Anesthesiology 2025-04-10

Abstract Brain accumulation of soluble oligomers the amyloid‐β peptide (AβOs) is increasingly considered a key early event in pathogenesis Alzheimer's disease (AD). A variety AβO species have been identified, both vitro and vivo , ranging from dimers to 24mers higher order oligomers. However, there no consensus literature regarding which are most germane AD pathogenesis. Antibodies capable specifically recognizing defined subpopulations AβOs would be valuable asset identification, isolation,...

10.1111/jnc.14118 article EN publisher-specific-oa Journal of Neurochemistry 2017-07-03

Background: The increasing trend of women with unilateral breast cancer to electively undergo contralateral prophylactic mastectomy in addition treatment the index has been controversial. authors set out better frame risks and benefits by evaluating outcomes a large, consecutive cohort patients. Methods: An institutional review board–approved single-surgeon (N.T.) experience (2013 2018) was conducted all patients treated immediate reconstruction. Patient characteristics, surgical pathologic...

10.1097/prs.0000000000005690 article EN Plastic & Reconstructive Surgery 2019-07-01

Background: Triggering receptor expressed on myeloid cells 2 (TREM2), a transmembrane immunoglobulin-superfamily receptor, is primarily such as macrophages and dendritic cells. TREM2 has been shown to be associated with diseases neurodegeneration, fatty liver, obesity, atherosclerosis. Currently, it become one of the hotspots in oncology research. However, role pan-cancer, especially pancreatic cancer, remains unclear. Methods: We used Tumor-immune System Interactions Database (TISIDB)...

10.21037/tcr-24-201 article EN Translational Cancer Research 2024-07-01

Objective The aim of the study was to identify prevalence, authorship, and type information pertaining topics in urogynecology on Instagram via hashtag content analysis. Methods A list 20 hashtags consisting common urogynecologic diagnoses, procedures, lay terms derived from American Urogynecologic Society’s “Patient Fact Sheets.” top 9 most recent 30 posts for each were reviewed authorship type. Content divided into following categories: educational; tagged but unrelated posts; pertinent...

10.1097/spv.0000000000000869 article EN Female Pelvic Medicine & Reconstructive Surgery 2020-04-13

Laminin is an extracellular matrix molecule that the major component of basement membrane and plays a key role in regulating various processes. However, association between laminin gene family prognosis pancreatic carcinoma has not been systematically investigated.

10.1016/j.ajg.2024.07.006 article EN cc-by-nc-nd Arab Journal of Gastroenterology 2024-07-21

Abstract Background After mastectomy and breast reconstruction, many patients experience upper extremity complications, such as pain, restriction in motion, lymphedema. Despite an aesthetically satisfactory outcome, these occurrences can diminish a patient's postoperative quality of life. Several studies have investigated the causes incidence complications. However, there is currently paucity data comparing function according to reconstruction technique. Methods A review was performed...

10.1055/s-0039-1698439 article EN Journal of Reconstructive Microsurgery 2019-10-23
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