Katalin Márta
- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Liver Disease Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Appendicitis Diagnosis and Management
- Gallbladder and Bile Duct Disorders
- COVID-19 Clinical Research Studies
- Childhood Cancer Survivors' Quality of Life
- Esophageal and GI Pathology
- Celiac Disease Research and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Gastroesophageal reflux and treatments
- Hormonal Regulation and Hypertension
- Adrenal Hormones and Disorders
- Eosinophilic Esophagitis
- Microscopic Colitis
- Helicobacter pylori-related gastroenterology studies
- Healthcare cost, quality, practices
- Lymphatic Disorders and Treatments
- Cancer survivorship and care
- Abdominal vascular conditions and treatments
- Inflammatory Bowel Disease
- Renal function and acid-base balance
- Adolescent and Pediatric Healthcare
Semmelweis University
2017-2024
University of Pecs
2016-2024
Vilnius University Hospital Santariskiu Klinikos
2020
Fejér Megyei Szent György Egyetemi Oktató Kórház
2018
Heim Pál Gyermekkórház
2017
Hungarian Academy of Sciences
2017
University of Szeged
2016-2017
Center for Translational Molecular Medicine
2017
Hypertriglyceridemia is the third most common cause of acute pancreatitis (AP). It has been shown that hypertriglyceridemia aggravates severity and related complications AP; however, detailed analyses large cohorts are contradictory. Our aim was to investigate dose-dependent effect on AP. AP patients over 18 years old who underwent triglyceride measurement within initial three days were included into our cohort analysis from a prospective international, multicenter registry operated by...
The in-hospital survival of patients suffering from acute pancreatitis (AP) is 95% to 98%. However, there growing evidence that discharged after AP may be at risk serious morbidity and mortality. Here, we aimed investigate the risk, causes, predictors most severe consequence post-AP period: mortality.A total 2613 well-characterized 25 centers were included followed by Hungarian Pancreatic Study Group between 2012 2021. A general a hospital-based population was used as control group.After an...
The incidence of acute pancreatitis (AP) and the prevalence metabolic syndrome (MetS) are growing worldwide. Several studies have confirmed that obesity (OB), hyperlipidemia (HL), or diabetes mellitus (DM) can increase severity, mortality, complications in AP. However, there is no comprehensive information on independent joint effect MetS components outcome Our aims were (1) to understand whether an AP (2) examine their combinations.From 2012 2017, 1435 cases from 28 centers included...
Introduction: Our meta-analysis indicated that aging influences the outcomes of acute pancreatitis (AP), however, a potential role for comorbidities was implicated, as well. Here we aimed to determine how age and modify in AP cohort-analysis Hungarian cases. Materials methods: Data patients diagnosed with by revised Atlanta criteria were extracted from Registry Pancreatic Patients. Outcomes interest mortality, severity, length hospitalization, local, systemic complications AP. Comorbidities...
Objective This study aimed to develop and validate a patient-reported outcome measure (PROM) in acute pancreatitis (AP) as an endpoint centred on the patient. Design A PROM instrument (PAtieNt-rePoRted OutcoMe scale pancreatItis, international proSpEctive cohort study, PAN-PROMISE scale) was designed based opinion of patients, professionals expert panel. The validated multicentre prospective describing severity AP quality life at 15 days after discharge main variables for validation. COSMIN...
Abstract Chronic pancreatitis (CP) is an end-stage disease with no specific therapy; therefore, early diagnosis of crucial importance. In this study, data from 1315 and 318 patients were analysed acute (AP) CP registries, respectively. The population the AP registry was divided into (n = 983), recurrent (RAP, n 270) 62) groups. prevalence in combination AP, RAP2, RAP3, RAP4 RAP5 + 0%, 1%, 16%, 50% 47%, respectively, suggesting that three or more episodes a strong risk factor for CP....
Abstract Introduction Non‐alcoholic fatty liver disease (NAFLD) is a proven risk factor for acute pancreatitis (AP). However, NAFLD has recently been redefined as metabolic‐associated (MAFLD). In this post hoc analysis, we quantified the effect of MAFLD on outcomes AP. Methods We identified our patients from multicentric, prospective International Acute Pancreatitis Registry Hungarian Pancreatic Study Group. Next, compared AP with and without individual components regarding in‐hospital...
Abstract Pancreatic necrosis is a consistent prognostic factor in acute pancreatitis (AP). However, the clinical scores currently use are either too complicated or require data that unavailable on admission lack sufficient predictive value. We therefore aimed to develop tool aid prediction. The XGBoost machine learning algorithm processed from 2387 patients with AP. confidence of model was estimated by bootstrapping method and interpreted via 10th 90th percentiles prediction scores. Shapley...
Introduction Acute pancreatitis (AP) is an inflammatory disease with no specific treatment. Mitochondrial injury followed by ATP depletion in both acinar and ductal cells a recently discovered early event its pathogenesis. Importantly, preclinical research has shown that intracellular delivery restores the physiological function of protects from cell injury, suggesting restoration energy levels pancreas therapeutically beneficial. Despite several high quality experimental observations this...
Background C-reactive protein level (CRP) and white blood cell count (WBC) have been variably used in clinical trials on acute pancreatitis (AP). We assessed their potential role. Methods First, we investigated studies which CRP or WBC, to describe current role AP. Second, extracted the data of 1435 episodes AP from our registry. WBC admission, within 24 hours onset pain highest values were analyzed. Descriptive statistical tools as Kruskal-Wallis, Mann-Whitney U, Levene's F tests, Receiver...