A5046076516- Satellite Communication Systems
- Insect symbiosis and bacterial influences
- Microplastics and Plastic Pollution
- Quantum Dots Synthesis And Properties
- Effects and risks of endocrine disrupting chemicals
- Enzyme Production and Characterization
- SARS-CoV-2 and COVID-19 Research
- Age of Information Optimization
- interferon and immune responses
- biodegradable polymer synthesis and properties
- Smart Grid Security and Resilience
- Software-Defined Networks and 5G
- Graphene and Nanomaterials Applications
- Infections and bacterial resistance
- Microbial bioremediation and biosurfactants
- Microfluidic and Capillary Electrophoresis Applications
- Polysaccharides and Plant Cell Walls
- Hepatitis Viruses Studies and Epidemiology
- PAPR reduction in OFDM
- Phytoplasmas and Hemiptera pathogens
- Network Time Synchronization Technologies
- Nanopore and Nanochannel Transport Studies
- Spacecraft Dynamics and Control
- Advanced Sensor and Energy Harvesting Materials
- Click Chemistry and Applications
Shanghai Electric (China)
2021-2025
Tianjin University
2018-2024
Shanghai Medical Information Center
2023-2024
Constellation Technology (United States)
2023
China Telecom (China)
2022
ShanghaiTech University
2021
Nanjing Tech University
2021
Collaborative Innovation Center of Chemical Science and Engineering Tianjin
2018
Nankai University
2016-2017
Tianjin International Joint Academy of Biomedicine
2017
The process of recycling poly(ethylene terephthalate) (PET) remains a major challenge due to the enzymatic degradation high-crystallinity PET (hcPET). Recently, bacterial PET-degrading enzyme, PETase, was found have ability degrade hcPET, but with low activity. Here we present an engineered whole-cell biocatalyst simulate both adsorption and steps in PETase achieve efficient hcPET. Our data shows that adhesive unit hydrophobin are functionally displayed on surface yeast cells. turnover rate...
Significance Guanylate-binding proteins (GBPs) belong to interferon-inducible GTPases and mediate a broad spectrum of innate immune responses against various pathogens. Their protective functions require oligomerization induced by nucleotide binding and/or catalysis, but the actual molecular mechanisms are still elusive. Here, we report crystal structures human GBP5 (hGBP5) in both its nucleotide-free state nucleotide-bound state, as well GBP2 (hGBP2). We show that hGBP5 forms closed...
Significance Mosquito-borne diseases cause more than 700,000 deaths annually. Wolbachia pipientis , an intracellular bacterium infecting many insect species, can manipulate host reproduction through cytoplasmic incompatibility (CI) and is being used in several promising strategies for controlling mosquito populations reducing the spread of mosquito-vectored viruses. Although key factors involved CI (called or Cifs) have been identified, molecular mechanisms induction rescue remain elusive....
We demonstrate a label-free, high-throughput cell separation method via SSAW-based acoustofluidic device with serpentine channel for clinical diagnosis and point-of-care analysis.
Abstract The multi‐mode heterogeneous network combines the advantages of high‐speed power line communication (HPLC) and high radio frequency (HRF), ensuring service quality meeting requirements for data transmission delay reliability even when devices are flexibly deployed. Queuing privacy entropy important metrics managing internet things (IoT) networks, which require collaborative optimization phase (server selection sub‐channel allocation) computing (computing resource to ensure low...
Abstract Cytoplasmic incompatibility (CI) results when Wolbachia bacteria-infected male insects mate with uninfected females, leading to embryonic lethality. “Rescue” of viability occurs if the female harbors same strain. CI is caused by linked pairs genes called factors (CifA and CifB). The co-evolution CifA-CifB may account in part for patterns documented infected different strains, but molecular mechanisms remain elusive. Here, we use X-ray crystallography AlphaFold analyze from strain w...
Nowadays, increasing analytical sensitivity is still a big challenge in constructing membrane-based fluorescence immunochromatography test strips (FICTS). However, the bioactivity of antibody (Ab) immobilized on line (T line) porous nitrocellulose membrane (PNM), which directly influences sensitivity, less studied. In this work, novel amphiphilic hydrophobin (HFBI) protein was introduced to modify T effectively retain Abs' bioactivity. The results indicated that HFBI could self-assemble PNM...
Hemicellulose is a highly abundant, ubiquitous, and renewable natural polysaccharide, widely present in agricultural forestry residues. The enzymatic hydrolysis of hemicellulose has generally been accomplished using β-xylosidases, but concomitantly increasing the stability activity these enzymes remains challenging. Here, we rationally engineered β-xylosidase from Bacillus clausii to enhance its by computation-aided design combining ancestral sequence reconstruction structural analysis....
Low water solubility and poor selectivity are two fundamental limitations that compromise applications of near-infrared (NIR) fluorescent probes.Methods: Here, a simple strategy can resolve these problems simultaneously was developed by using novel hybrid protein named RGD-HFBI is produced fusion hydrophobin HFBI arginine-glycine-aspartic acid (RGD) peptide.This unique inherits self-assembly targeting functions from RGD peptide respectively.Results: Boron-dipyrromethene (BODIPY) used as...
Abstract Low water solubility and poor membrane permeability are major disadvantages that compromise applications of most fluorescent dyes. To resolve these problems, herein, using Boron-dipyrromethene (BODIPY) as a model dye, for the first time, we provide new strategy rapid efficient production water-soluble membrane-permeable dye by mixing with an amphiphilic protein named hydrophobin. Data shows BODIPY could be effectively solubilized dispersed in 200 μg/mL hydrophobin simple sonication....
The existing zoonotic coronaviruses (CoVs) and viral genetic variants are important microbiological pathogens that cause severe disease in humans animals. Currently, no effective broad-spectrum antiviral drugs against emerging CoVs available. CoV main protease (Mpro) plays an essential role replication, making it ideal target for drug development. However, the structure of Deltacoronavirus Mpro is still unavailable. Porcine deltacoronavirus (PDCoV) a novel belongs to genus causes atrophic...
Reliability mapping of 5G low orbit constellation network slice is an important means to ensure link communication. The problem state space explosion a typical problem. deep reinforcement learning method introduced. Under the integrated architecture based on software definition (SDN) and function virtualization (NFV), resource requirements constraints virtual (VNF) are comprehensively considered build reliability model, model parameters trained learned by using learning, solve in process...
In this paper, we propose an offloading method for edge computing that takes into account the energy consumption of task requests, constructs and analyzes a co-tracked multi-star structure, calculates individual delay builds multi-layer projection pursuit (MLEPP) model to calculate optimal location. The experimental results show has lower average higher efficiency.
The Zinc-air batteries continuous power generation which is designed by our task group realizes the discharge of zinc electrode in motion and solves problem self-discharge battery. battery control system this paper to realize automatic operation improve efficiency generation. design device based on combination mechanical electrical technology.this use PIC16F877A microcontroller as core main equipment for devices (analog acquisition stepper motor) with technology analysed. ideas software...
Aiming at the high concurrency and delay insensitive services in VPP information interaction, such as collection reporting of basic load data, aiming problem that it excessively occupies resources power communication system. In this paper, a method convergence processing transmission on platform is proposed. Simulation results show proposed can effectively remove redundancy packets achieve better compression performance.
The current conventional routing optimization methods for low-orbit constellation networks have a large impact on satellite energy consumption, which link-state-based method is proposed. By constructing state-space excitation function based node and delay requirements, constraining the function. analysis of experimental results shows that strategy can effectively reduce consumption under proposed method.