A5103182185- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Gestational Diabetes Research and Management
- Cancer therapeutics and mechanisms
- Healthcare Education and Workforce Issues
- Monoclonal and Polyclonal Antibodies Research
- Magnesium Alloys: Properties and Applications
- Microbial Natural Products and Biosynthesis
- Maternal Mental Health During Pregnancy and Postpartum
- Aluminum Alloys Composites Properties
- Pharmacological Effects of Natural Compounds
- Assisted Reproductive Technology and Twin Pregnancy
- Aluminum Alloy Microstructure Properties
- Antioxidant Activity and Oxidative Stress
- Salivary Gland Disorders and Functions
- Bacteriophages and microbial interactions
- RNA and protein synthesis mechanisms
- Bioactive Compounds and Antitumor Agents
- Cancer-related Molecular Pathways
- Job Satisfaction and Organizational Behavior
- Glycosylation and Glycoproteins Research
- Bacterial Genetics and Biotechnology
- Health, Environment, Cognitive Aging
- Computational Drug Discovery Methods
- Biopolymer Synthesis and Applications
Tohoku Medical Megabank Organization
2015-2024
Tohoku University
2013-2024
Kanazawa University
2023-2024
Kyoto University
2017-2019
Graduate School USA
2019
Tohoku Medical and Pharmaceutical University
2016-2019
Tohoku University Hospital
2018
TEPCO (Japan)
2016-2017
Chiba University
2000-2014
National Defense Academy of Japan
2013
Abstract Background Alzheimer’s disease (AD) is the most common cause of dementia among elderly. To clarify pathogenesis AD, thousands reports have been accumulating. However, knowledge signaling pathways in field AD has not compiled as a database before. Description Here, we constructed publicly available pathway map called “AlzPathway” that comprehensively catalogs AD. We collected and manually curated over 100 review articles related to built an using CellDesigner. AlzPathway currently...
Friction welding was carried out between TiNi alloy and austenitic stainless steel with without a Ni interlayer. When welded to the interlayer, large amount of brittle Fe 2 Ti intermetallic compound formed at weld interface. The formation this led degradation joint strength. interlayer changed microstructures interface improved A fracture occurred TiNi. free from consisted mainly 3 After as reaction layer, eutectic base alloy. layer structure tends form periphery, where temperature would be...
Abstract Autism spectrum disorder (ASD) has phenotypically and genetically heterogeneous characteristics. A simulation study demonstrated that attempts to categorize patients with a complex disease into more homogeneous subgroups could have power elucidate hidden heritability. We conducted cluster analyses using the k-means algorithm number of 15 based on phenotypic variables from Simons Simplex Collection (SSC). As preliminary study, we conventional genome-wide association (GWAS) data set...
PURPOSE. Lutein is a carotenoid mainly found in green leafy vegetables and located the macula lutea human eye. Since humans cannot synthesize lutein de novo, it must be digested as food. The physiological importance of an orally administered compound depends on its interaction with target tissues. It therefore important to clarify absorption mechanism intestine. Cholesterol membrane transporters Niemann-Pick C1 Like 1 (NPC1L1) scavenger receptor class B type (SR-B1) are involved intestinal...
Purpose: To elucidate drug use before and during pregnancy in Japan. Methods: The Japan Environment Children’s Study (JECS) is an ongoing nationwide birth cohort study. We analyzed data from JECS involving cases where drugs were used for 12 months was diagnosed, between the time of diagnosis until week pregnancy, after pregnancy. Results: 97,464 pregnant women. percentages women who had taken one or more supplements 78.4%, 57.1%, 68.8% respectively. Excluding iron supplements, folic acid,...
Objective: To survey prevalence and risk factors for paternal postpartum depression symptoms at one 6 months in Japan.Material methods: The study participants enrolled the prospective birth cohort of an adjunct Japan Environment Children's Study. Postpartum were evaluated using Japanese version Edinburgh Postnatal Depression Scale (EPDS-J). cut-off scores on EPDS-J eight maternal was nine, respectively. multivariate logistic regression included adjustment age, number children family, family...
Exclusive photoinduced energy transfer and switching of its direction by rectangular π-extension nanographene were achieved in porphyrin–nanographene linked systems.
Abstract Hypertensive disorders of pregnancy (HDP) are associated with poor maternal and neonatal prognoses. Although several studies have indicated an effect secondhand smoke (SHS) exposure on HDP, such evidence is lacking in Japan. Therefore, we analyzed data from the Japan Environment Children’s Study, a large-scale epidemiological investigation, to elucidate possible link between SHS HDP risk. Data were obtained all-birth fixed datasets included information 104,062 fetuses their parents....
Abstract Lutein is a carotenoid found mainly in green leafy vegetables and located the macula lutea human eye. An intake of lutein as food needed since humans cannot synthesize it de novo . Although has received much attention recently due to its antioxidant activities, little information about pharmacokinetic properties available. emulsion formulation was used pharmacokinetics after oral administration rats investigated. The bioavailability using this calculated be 5.20%. It that large...
Abstract Objective This study aimed to clarify the correlation between 2011 Great East Japan Earthquake and domestic violence (DV) against pregnant females after disaster in Miyagi Prefecture, an area damaged by earthquake tsunami. Methods We analyzed 7600 from June December 2011. The incidence of physical mental DV proportions inland, north coastal, south coastal areas Prefecture nationwide were calculated, a chi-square test was conducted for comparison. risk factors estimated with...