A5062567082- Nutritional Studies and Diet
- Blood Pressure and Hypertension Studies
- Sodium Intake and Health
- Health disparities and outcomes
- Disaster Response and Management
- Health, Environment, Cognitive Aging
- Nutrition and Health in Aging
- Liver Disease Diagnosis and Treatment
- Geriatric Care and Nursing Homes
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Posttraumatic Stress Disorder Research
- Birth, Development, and Health
- Genetic Associations and Epidemiology
- Diet and metabolism studies
- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Disease Prevention
- Homelessness and Social Issues
- Body Composition Measurement Techniques
- Nutrition, Genetics, and Disease
- Sleep and related disorders
- Disaster Management and Resilience
- Obesity, Physical Activity, Diet
- Renal function and acid-base balance
- Climate Change and Health Impacts
- Diabetes, Cardiovascular Risks, and Lipoproteins
Tohoku Medical Megabank Organization
2015-2025
Tohoku University
2013-2025
Tohoku University Hospital
2024
General Department of Preventive Medicine
2024
Graduate School USA
2023
Gunma University
1987
Background: We established a community-based cohort study to assess the long-term impact of Great East Japan Earthquake on disaster victims and gene-environment interactions incidence major diseases, such as cancer cardiovascular diseases.
Abstract Risk factors for hypertension have been emphasized in the Japanese Society of Hypertension Guidelines Management Hypertension. However, large-scale studies on association smoking, potassium excretion, and gamma-glutamyl transferase level with BP population are limited. We conducted a cross-sectional study to examine between risk systolic blood pressure Tohoku Medical Megabank Community-based Cohort Study (23,446 men 38,921 women aged ≥20 years). A model adjusted age, body mass...
Epidemiological studies have demonstrated that the urine sodium-to-potassium (Na/K) ratio is more positively associated with high blood pressure and cardiovascular disease risk than either sodium or potassium excretion alone. In this consensus statement, we recommend using average Na/K of casual urines randomly taken in various times on at least four days a week for reliable individual estimate because day-to-day intraday variability within individuals. Although continuous positive...
Abstract No study, to our knowledge, has constructed a polygenic risk score based on clinical blood pressure and investigated the association of genetic lifestyle risks with home hypertension. We examined associations combined hypertension In cross-sectional study 7027 Japanese individuals aged ≥20 years, we developed body mass index, alcohol consumption, physical activity, sodium-to-potassium ratio, categorized into ideal, intermediate, poor lifestyles. A was target data ( n = 1405) using...
Social capital has been considered an important factor affecting mental-health outcomes, such as psychological distress in post-disaster settings. Although disaster-related house condition and displacement could affect both social distress, limited studies have investigated interactions. This study aimed to examine the association between taking into consideration interaction of after Great East Japan Earthquake 2011.Using data from 3793 adults living Shichigahama, Miyagi Prefecture, Japan,...
Recently, the sodium (Na)/potassium (K) ratio was reported to be associated with blood pressure (BP). A Na/K self-monitoring device using spot urine established recently. Here, we assessed whether urinary change measured BP in a health checkup setting. We targeted 12,890 participants who attended Tome City, Miyagi between 2017 and 2018. City introduced measurements during checkups since 2017. For each year, compared baseline characteristics according level. relationship multiple regression...
Abstract This study aimed to investigate the association of combination birth weight and current body mass index (BMI) with risk hypertension in adulthood. cross-sectional used data from Tohoku Medical Megabank Community-based Cohort Study conducted Japan. A total 10,688 subjects aged ≥20 years were eligible. We calculated least square (LS) means systolic blood pressure (SBP) trend tests performed evaluate linear relationships between categories SBP. also a multivariate logistic regression...
The primary prevention of atrial fibrillation (AF), which increases mortality through complications including stroke and heart failure, is important. Excessive salt intake low potassium are risk factors for cardiovascular disease; however, their association with AF remains inconclusive. This study investigated the between sodium- potassium-related urinary markers prevalence. Data from Tohoku Medical Megabank Project Community-based Cohort Study were used in this cross-sectional study....
Background Natural disasters may have negative health effects on survivors. However, long-term observations this are lacking. Therefore, study investigated the association between degree of housing damage caused by Great East Japan Earthquake (GEJE) and all-cause mortality using data from cohort conducted Tohoku Medical Megabank (TMM) Project in disaster-stricken areas. Methods The community-based TMM which a baseline survey May 2013 to March 2016 collected questionnaires blood urine tests....
Objectives Previous studies have assessed the impact of active smoking on mortality using population-attributable fraction (PAF). However, these not included second-hand (SHS), potentially underestimating smoking’s impact. We compared PAF from alone with PAF, including SHS exposure. Design Prospective cohort study. Setting A community-based study in Japan. Participants 40 796 participants aged ≥20 years. Main outcome measures was defined as inhaling someone else’s cigarette smoke at...
Abstract Multiple sclerosis (MS) is a major demyelinating disease of the central nervous system; however, its exact mechanism unknown. This study aimed to elucidate profile white blood cells (WBCs) in acute phase an MS attack. Sixty-four patients with at time diagnosis and 2492 age- sex-adjusted healthy controls (HCs) were enrolled. Data regarding cell counts compared between groups. The total WBC ( p < 0.0001), monocyte basophil = 0.0027), neutrophil 0.0001) higher group than HC group,...
The purpose of this study was to report the basic profile Miyagi Prefecture part a repeated center-based survey during second period Tohoku Medical Megabank Community-Based Cohort Study (TMM CommCohort Study), as well participants' characteristics based on their participation type in baseline survey.
Background: The relationship between blood cell profiles, including hemoglobin (Hb) levels and inflammatory hematological ratios, mental health problems currently remains unclear. Aim: This study aimed to investigate the profiles issues, depressive state sleep disturbance, while adjusting for potential demographic confounders. Methodology: retrospective, cross-sectional, observational used a population-based medical database from Tohoku Medical Megabank Project with more than 60,000...
Background: Patients with physical disease are known to suffer considerable psychological distress. Social support may confound the association between and Population-based epidemiological studies have not been conducted on history of disease, distress social support. Methods: Using cross-sectional data from 2006, we studied 43 487 community-dwelling people aged ≥40 years living in Japan. We examined 13 self-reported histories evaluated using Kessler 6-item scale (K6), defined as ≥13 points...
It has been reported that chronic inflammation may play an important role in the pathogenesis of several serious diseases and could be modulated by diet. Recently, Dietary Inflammatory Index (DII®) was developed to assess inflammatory potential overall The DII as relevant various but not validated Japanese. Thus, present study, we analyzed relationship between scores high-sensitivity C-reactive protein (hs-CRP) levels a Japanese population.Data National Integrated Project for Prospective...
Abstract The sodium-to-potassium (Na/K) ratio is known to be associated with blood pressure (BP). However, no reference value has been established since the urinary Na/K (uNa/K) have diurnal and day-to-day variations. Therefore, we investigated number of days required yield a better association between morning uNa/K home BP (HBP) determined that can used as in participants who are not taking antihypertensive medication. This was cross-sectional study using data from Tohoku Medical Megabank...
A higher body fat percentage is associated with hypertension, even in non-obese individuals. The difference composition may be related to hypertension. mass index (FMI) and fat-free (FFMI) are proposed indicators of composition. This study aimed examine the relationship a combination FMI FFMI hypertension.We conducted cross-sectional 5,058 men 11,842 women aged ≥ 20 years Miyagi Prefecture, northeastern Japan. were calculated as divided by height squared, respectively. indices classified...
Fat mass and fat-free affect glycated hemoglobin A1c (HbA1c) levels blood glucose levels, respectively. The aim of the present study was to examine association between fat index with HbA1c.We carried out a cross-sectional that included 3,731 men 9,191 women aged ≥20 years, living in Miyagi Prefecture, Japan, who were not treated for diabetes. calculated as divided by height squared, indices classified into sex-specific quartiles combined 16 groups. An analysis covariance used assess...
Although several studies have shown an inverse association between lung function and hypertension, few examined the hypertension among never-smokers, no study has investigated home hypertension. We associations in a Japanese population.We conducted cross-sectional of 3728 men 8795 women aged 20 years or older living Miyagi Prefecture, Japan. Lung was assessed using forced expiratory volume at 1 s (FEV ) vital capacity (FVC), measured by spirometry. Hypertension defined as casual blood...
We examined the association between carotid intima medica thickness (cIMT) and risk factors for atherosclerosis based on Japan Atherosclerosis Society 2022 Prevention Guideline.
Accumulating data on the associations between food consumption and lipid composition in body is essential for understanding effects of dietary habits health.