- Renal Transplantation Outcomes and Treatments
- Transplantation: Methods and Outcomes
- Pancreatic function and diabetes
- Testicular diseases and treatments
- Circular RNAs in diseases
- Genetics and Neurodevelopmental Disorders
- Organ Transplantation Techniques and Outcomes
- Health Literacy and Information Accessibility
- Cancer-related gene regulation
- Cancer, Lipids, and Metabolism
- Bipolar Disorder and Treatment
- Wikis in Education and Collaboration
- Biomarkers in Disease Mechanisms
- Liver Disease Diagnosis and Treatment
- Diabetes Treatment and Management
- Tryptophan and brain disorders
- Social Media in Health Education
- Lipoproteins and Cardiovascular Health
- Inflammatory Biomarkers in Disease Prognosis
- Thermal Radiation and Cooling Technologies
- Mechanical and Optical Resonators
- vaccines and immunoinformatics approaches
- Spinal Hematomas and Complications
- Case Reports on Hematomas
- Toxoplasma gondii Research Studies
First Affiliated Hospital Zhejiang University
2012-2023
Blood Center of Zhejiang Province
2023
Second Affiliated Hospital of Nanjing Medical University
2023
Zhejiang University
2013-2023
National Health and Family Planning Commission
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2023
Nantong University
2022
Southern Medical University
2021
Nanfang Hospital
2021
First Affiliated Hospital of Henan University
2020
TikTok was an important channel for consumers to access and adopt health information. But the quality of content in remains underinvestigated.Our study aimed identify upload sources, contents, feature information gallstone disease videos on further evaluated factors related video quality.We investigated first 100 gallstone-related analyzed these videos' content, characteristics. The using quantitative scoring tools such as DISCERN instrument, Journal American Medical Association (JAMA)...
Abstract Purpose To investigate the brain iron deposits in patients with Alzheimer's disease (AD) and healthy age‐matched controls using phase imaging. Materials Methods Twenty‐six AD 24 were recruited. A three‐dimensional high‐resolution, gradient‐echo sequence was used to acquire data coronal plane. high‐pass filter remove variation caused by field inhomogeneity. The regions evaluated included bilateral putamen, globus pallidus, head body of hippocampus. Results Significantly lower values...
Circular RNAs (circRNAs) play a significant role in the initiation and progression of various cancers, including hepatocellular carcinoma (HCC). syntaxin 6 (circSTX6, also known as hsa_circ_0007905) has been identified microRNA (miRNA) sponge pancreatic adenocarcinoma. However, its full range functions terms protein scaffold translation remain largely unexplored context HCC.The expression circSTX6 encoded was examined HCC tumour tissues. N6 -methyladenosine (m6 A) on verified quantified by...
Our previous studies have shown that microRNA-383 (miR-383) expression is downregulated in the testes of infertile men with maturation arrest (MA). Abnormal testicular miR-383 may potentiate connections between male infertility and germ cell tumors. However, mechanisms underlying targeting functions during spermatogenesis remain unknown. In this study, we found fragile X mental retardation protein (FMRP) was associated 88 miRNAs mouse testis including miR-383. Knockdown FMRP NTERA-2 (NT2)...
Lipoprotein(a) [Lp(a)] is a lipoprotein with potent atherogenic and thrombogenic potential. Its role in patients acute coronary syndrome (ACS) combined three-vessel disease (TVD) remains unclear. This study aimed to investigate the correlation between Lp(a) levels occurrence of major adverse cardiovascular events (MACE) ACS TVD. Patients who underwent angiography were diagnosed TVD selected for study. divided into three groups based on their levels. The MACE was evaluated using univariate...
Large language models (LLMs) acquire information from pre-training corpora, but their stored knowledge can become inaccurate or outdated over time. Model editing addresses this challenge by modifying model parameters without retraining, and prevalent approaches leverage hypernetworks to generate these parameter updates. However, they face significant challenges in lifelong due incompatibility with LLM that dynamically change during the process. To address this, we observed hypernetwork-based...
Background The use of the immunosuppressive drug tacrolimus (TAC) is related to new onset diabetes after transplantation. Herein, we examined effect intraperitoneal administered TAC on intestinal glucose absorption in mice. Methods Animals received low, medium, or high dose (0.5, 1, 5 mg/kg/d, respectively), 0.9% saline solution (control) for 14 days. Oral tolerance test (OGTT), insulin concentration test, and serum measurements was performed days exposure. Plasma assessed electrogenic were...
Abstract Mental disorders are severe, disabling conditions with unknown etiology and commonly misdiagnosed when clinical symptomology criteria solely used. Our previous work indicated that combination of serum levels multiple proteins in tissue plasminogen activator (tPA)-brain-derived neurotrophic factor (BDNF) pathway improved accuracy diagnosis major depressive disorder (MDD). Here, we measured tPA, inhibitor-1 (PAI-1), BDNF, precursor-BDNF (proBDNF), tropomyosin-related kinase B (TrkB)...
Abstract Idiopathic diseases of the reproductive system are important factors leading to male infertility. Many studies have shown that microRNAs (miRNAs) regulate expression multiple genes play a significant role in spermatogenesis and development. We previously showed microRNA-210 (miR-210) is one markedly upregulated testes sterile males with maturation arrest (MA). However, miR-210 remains unknown. In this study, we found highly expressed not only patients MA but also cryptorchidism....
Background The internet has changed the way of people acquiring health information. Previous studies have shown that Wikipedia is a reasonably reliable medical resource, and it been ranked higher than other general websites in various search engines. Baidu Encyclopedia one most popular encyclopedia China. However, no quality content provided Encyclopedia. Objective This study aimed to evaluate liver disease information by (in English) Chinese) perform comparison timeliness articles published...
Misdiagnosis between major depressive disorder (MDD) and bipolar depression (BD) is quite common. Our previous study found significantly lower serum VGF (non-acronymic) in MDD patients. However, it unclear whether same changes occur BD Therefore, we aimed to investigate the relationship levels General information, scores of 17-item Hamilton Depression Rating Scale (HDRS), fasting blood samples all participants including 30 patients, 20 healthy controls (HC) were collected. Serum measured by...
Pancreas transplantation is the definite treatment for type 1 diabetes that enables achievement of long-term normoglycemia and insulin independence.However Post-Transplantation Pancreatitis (PTP) due to ischemia reperfusion (IR) injury preservation a major complication in pancreas transplantation.Owning potential anti-inflammatory effect Cisplatin (Cis) liver IR injury, we have examined if Cis could attenuate PTP using murine model.We found able prevent inflammatory response PTP.Pretreatment...
Purpose: Mood disorders are recurrent chronic with fluctuating mood states and energy, misdiagnosis is common when based solely on clinical interviews because of overlapping symptoms. Because may lead to inappropriate treatment poor prognosis, finding an easily implemented objective tool for the discrimination different very necessary urgent. However, there has been no accepted until now. Recently, BICC1 identified as a candidate gene relating major depressive disorder (MDD). Therefore, aim...
We propose a novel and experimentally feasible approach to achieve high-efficiency ground-state cooling of mechanical oscillator in an optomechanical system under the deeply unresolved sideband condition with assistance both intracavity extracavity squeezing. In scheme, degenerate optical parametric amplifier is placed inside cavity, generating squeezing; besides, cavity driven by externally generated squeezing light, namely The quantum interference effect can completely suppress...
Lumbar spinal epidural lipomatosis (SEL) is a rare condition characterized by the pathological proliferation of adipose tissue in space canal. This study presents case 59-year-old male with lumbar SEL treated effectively short term through arthroscopic-assisted uniportal surgery (AUSS) combined modified circle-drawing unilateral laminotomy bilateral decompression (ULBD) technique.
Background: Standard treatments for nonparasitic hepatic cysts (NPHCs) include laparoscopic deroofing (LD), percutaneous aspiration, and alcohol sclerotherapy. However, these have limitations. LD sclerotherapy, example, fail to prevent NPHC recurrences, although sclerotherapy is satisfactorily effective in treating small (diameter <5 cm), which do not usually need treatment. The present study introduces a novel surgical procedure, enucleation with intact cyst (LEIC), may postoperative...
This paper set up an evaluation index system for green building supplier selection mode based on the content and feature of supply chain management , introduced combined method advanced entropy-revised G1 combination weighting TOPSIS. simplifies computation TOPSIS avoids problem subjectively deciding weight . At last, example was given to evaluate feasibility this method.
Background: Venous thromboembolic events (VTE) are common causes of morbidity and mortality in glioblastoma patients. Mutation the isocitrate dehydrogenase 1 enzyme (IDH1) is frequent secondary results altered metabolomics. Objectives: This study evaluates whether IDH-1 status correlates with incidence VTE Methods: Observational 398 cases patients glioblastoma, who all underwent surgery a regional Neurosurgical centre between April 2012 December 2014. IDH -1 Tissue factor (F3) protein...
Objective To investigate the occurrence and influencing factors of early allograft dysfunction (EAD) in patients receiving donation after cardiac death (DCD) liver Transplantation. Methods Forty-five received orthotopic transplantation our center during January 2016 May were included this study. Based on EAD, divided into EAD group non-EAD group. Perioperative data donors recipients collected to analyze risk effect short-term prognosis patients. Results In 45 patients, incidence...