- Vascular Malformations Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurosurgical Procedures and Complications
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Traumatic Brain Injury and Neurovascular Disturbances
- Spinal Fractures and Fixation Techniques
- Moyamoya disease diagnosis and treatment
- Vascular Malformations and Hemangiomas
- Spinal Hematomas and Complications
- Meningioma and schwannoma management
- Aortic Disease and Treatment Approaches
- Advanced ceramic materials synthesis
- Thermal properties of materials
- COVID-19 and Mental Health
- Fuel Cells and Related Materials
- Conducting polymers and applications
- Cerebral Venous Sinus Thrombosis
- Lymphoma Diagnosis and Treatment
- Cardiovascular Conditions and Treatments
- Retinal and Macular Surgery
- Anesthesia and Pain Management
- Trigeminal Neuralgia and Treatments
- Vitamin C and Antioxidants Research
Tianjin Medical University
2025
Capital Medical University
2016-2025
University of Electronic Science and Technology of China
2024
Guangdong Academy of Medical Sciences
2023-2024
Guangdong Provincial People's Hospital
2023-2024
Southern Medical University
2023-2024
Shantou University
2024
Shantou University Medical College
2024
VA Sepulveda Ambulatory Care Center
2024
University of California, Los Angeles
2024
Brain and spinal arteriovenous malformations are congenital lesions causing intracranial haemorrhage or permanent disability especially in young people. We investigated whether the vast majority all brain associated with detectable tumour-related somatic mutations. In a cohort of 31 patients (21 10 malformations), tissue paired blood samples were analysed ultradeep next generation sequencing panel 422 common tumour genes to identify used droplet digital polymerase chain reaction confirm...
Abstract Background In the post-pandemic era, a wide range of COVID-19 sequelae is growing health concern. However, risks digestive diseases in long COVID have not been comprehensively understood. To investigate long-term risk among patients. Methods this large-scale retrospective cohort study with up to 2.6 years follow-up (median follow-up: 0.7 years), group ( n = 112,311), contemporary comparison 359,671) and historical 370,979) predated outbreak were built using UK Biobank database. Each...
For participants with intracranial aneurysm who underwent stent treatment, light transmission aggregation–guided antiplatelet therapy helped reduce ischemic events without increasing bleeding risks.
To compare clinical efficacy and quality of life (QoL) outcomes between minimally invasive surgery conservative treatment for type II fragility fractures the pelvis (FFP II). A total 150 patients with FFP II, treated at our hospital from January 2019 to December 2022, were included in this study. The mean follow-up period was 22 ± 5 months. Patients divided into two groups: 68 assigned group 82 group. Clinical assessed using Majeed questionnaire self-reported Short Musculoskeletal Function...
The categorization of pigmented purpuric dermatosis (PPD) as a form cutaneous lymphoid dyscrasia has been suggested. Phenotypic and molecular studies were done on 43 patients with PPD. used capillary gel electrophoresis T-cell receptor beta multiplex polymerase chain reaction assay. There 2 principal categories: polyclonal PPD represented by 22 cases monoclonal variants comprising 21 cases. Monoclonal had extensive skin lesions. An identical restricted repertoire independent time location...
The natural history of intradural spinal cord arteriovenous shunts is unknown. We performed an observational study in a consecutive patient cohort with symptomatic who were admitted to three institutes investigate the clinical course this complex disease, which would provide valuable evidence inform decision-making. patients from initial presentation occurrence deterioration, initiation treatment, or last follow-up was analysed. Patients at least 1 month observation included study. Clinical...
To compare the subsequent fertility and risk of recurrence an ectopic pregnancy (EP) in women who had EP, according to type surgical treatment they received--that is, salpingectomy, salpingostomy or tubal anastomosis.
OBJECTIVE Isolated spinal aneurysms (ISAs) are rare causes of subarachnoid hemorrhage (SAH), which encompass a highly heterogeneous group clinical entities with multifarious pathogeneses, characteristics, and treatment strategies. Therefore, knowledge about the ISAs remains inadequate. In this study, authors present comprehensive analysis data associated at their institutions to enhance understanding disease. METHODS Patients confirmed by angiography or surgery authors’ between 2015 2022...
Background Arteriovenous shunts below conus medullaris (AVS-BC) are understudied, particularly those associated with spinal dysraphism. This study aimed to refine the classification and management of AVS-BC. Methods A retrospective analysis patients AVS-BC from two centers over decades was performed, focusing on clinical presentations, angioarchitecture, treatment outcomes. classified into eight subtypes based dural relation, dysraphism presence. Treatment efficacy evaluated using changes in...
The mechanisms of hypertrophic cardiomyopathy (HCM) pathogenesis can be investigated by determining the differences between healthy and disease states at molecular level. In present study, large‑scale transcriptome sequencing was performed to compare mRNA expression in patients with HCM control groups using an Illumina platform. Compared genome background, 257 differentially expressed genes (DEGs) were identified which 62 downregulated 195 upregulated. Reverse transcription‑quantitative...
Lipoprotein-associated phospholipase A2 (Lp-PLA2) probably plays an important role in the development of acute coronary syndrome (ACS). However, alterations Lp-PLA2 levels during ACS and its association with cardiovascular outcome are unclear. Our aim was to investigate change patients ACS. A total 79 came from care unit (CCU) between June 1, 2015 August 31, 2016 this longitudinal study. Serum Lp-PLA2, troponin I, creatine kinase isoenzymes MB (CK-MB) were measured at admission, on first...
The natural history of spinal cord cavernous malformations (SCCMs) remains relatively unclear.To investigate the for hemorrhagic risks and neurological outcomes, as well relevant predicting factors, SCCMs.All patients between 2002 2019 with diagnosis SCCMs were identified retrospectively. An observational study conservative management was performed to reveal SCCMs.We 305 in full cohort, including 126 who conservatively treated at least 6 months (median period, 24.0 months). Forty-five...
Pediatric spinal perimedullary arteriovenous fistula (PMAVF) is rare but may cause permanent disability. We aim to summarize the clinical features of pediatric PMAVFs and our experience in their treatment evaluate effect endovascular a large cohort.From 2008 2017, 51 patients (<14 years' old) treated with techniques were retrospectively reviewed, including 24 type IVb (47.1%) 27 IVc (52.9%) lesions. Clinical features, radiological findings, treatment, outcomes evaluated.Thirty-eight boys...
Pial arteriovenous fistulas (PAVFs) are rare and mostly observed in children. However, the overall angioarchitecture, clinical features, treatments long-term prognosis for pediatric patients remain unclear.Clinical data of consecutive 42 PAVFs were documented analysed. According to differences age distribution they split into a younger group (≤3 years old; 20 cases) an older (3-14 22 cases).Their mean was 4.9±3.9 years, preoperative modified Rankin Scale (mRS) score 1.64±1.57. Fourteen...