- Foot and Ankle Surgery
- Orthopedic Surgery and Rehabilitation
- Tendon Structure and Treatment
- Congenital Heart Disease Studies
- Cognitive Functions and Memory
- Child and Animal Learning Development
- Cardiac, Anesthesia and Surgical Outcomes
- Diabetic Foot Ulcer Assessment and Management
- Sepsis Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Dementia and Cognitive Impairment Research
- Cardiac Structural Anomalies and Repair
- Coronary Artery Anomalies
- Airway Management and Intubation Techniques
- Tracheal and airway disorders
- Aging and Gerontology Research
- Sports injuries and prevention
- Cognitive Abilities and Testing
- Memory Processes and Influences
- Acute Kidney Injury Research
- Cardiac Valve Diseases and Treatments
- Total Knee Arthroplasty Outcomes
- Educational Practices and Challenges
- Influenza Virus Research Studies
- Foreign Body Medical Cases
Georgia State University
2023-2025
University Hospital Coventry
2013-2025
Women's and Children's Hospital
2012-2024
Peter Doherty Institute
2023-2024
The University of Melbourne
2023-2024
The University of Adelaide
2016-2023
Women's and Children's Health Network
2022-2023
University of Toledo
2023
University Hospitals Coventry and Warwickshire NHS Trust
2009-2022
Gwinnett College
2015-2022
Aaron J. Kelly, Marcella Sackett, Neena Din, Ellen Quardokus, and Yves V. Brun Departments of Biology Chemistry, Indiana University, Bloomington, 47405 USA
Age-related declines in capabilities may compromise older adults' ability to maintain their homes, threatening successful aging place. Structured interviews were conducted with 44 independently living adults (mean age = 76.1, standard deviation 4.7) discuss difficult home maintenance tasks and how they managed those tasks. Solutions managing difficulties categorized as person-related or environment-related. The majority (85%) of responses solutions. An understanding the specific challenges...
Mounting evidence has shown that critically ill patients are commonly thiamine deficient. We sought to test the hypothesis with septic shock exposed would demonstrate improved lactate clearance and more favorable clinical outcomes compared those not receiving thiamine.Retrospective, single-center, matched cohort study.Tertiary care academic medical center.Adult admitted an International Classification of Diseases, 9th Edition, or 10th diagnosis code either medicine surgery ICU.None.Patients...
Background— Echocardiographic screening for rheumatic heart disease (RHD) is becoming more widespread, but studies to date have used different echocardiographic definitions. The World Heart Federation has recently published new criteria the diagnosis of RHD. We aimed establish prevalence RHD in high-risk Indigenous Australian children using these and compare findings with a group at low risk Methods Results— Portable echocardiography was performed on aged 5 to15 years living remote...
We examined the association between fluid overload and major adverse kidney events in critically ill patients requiring continuous renal replacement therapy for acute injury.Retrospective cohort study.ICU a tertiary medical center.Four-hundred eighty-one adults injury.None.Fluid was assessed as balance from admission to initiation, adjusted body weight. Major were defined composite of mortality, therapy-dependence or inability recover 50% baseline estimated glomerular filtration rate (if not...
<h3>Importance</h3> Platelet-rich plasma injections are used as a treatment for chronic midportion Achilles tendinopathy, but evidence this is limited. <h3>Objective</h3> In adults with to assess the effects of single platelet-rich injection, compared sham on outcome Victorian Institute Sport Assessment-Achilles (VISA-A) score (a composite measure tendinopathy severity). <h3>Design, Setting, and Participants</h3> A participant-blinded, multicenter randomized clinical trial that included 240...
Numerous studies have found that working memory capacity and perceptual speed predict variation in fluid intelligence. Within the cognitive ageing literature, accounts for substantial variance However, within young adults, interrelationships among these three abilities are less clear. The current work investigated relationships via confirmatory factor analyses structural equation modelling using tasks with verbal, spatial, numerical content. results indicate were not related a large,...
Abstract Objective Administration of diuretics has been shown to assist fluid management and improve clinical outcomes in the critically ill post-shock resolution. Current guidelines have not yet included standardization or guidance for diuretic-based de-resuscitation patients. This study aimed evaluate impact a multi-disciplinary protocol diuresis-guided ill. Methods was pre-post single-center pilot within medical intensive care unit (ICU) large academic center. Adult patients admitted...
BackgroundPatients with Achilles tendon rupture who have non-operative treatment traditionally been treated immobilisation of the in plaster casts for several weeks. Functional bracing is an alternative that allows earlier mobilisation, but evidence on its effectiveness and safety scarce. The aim UKSTAR trial was to compare functional quality-of-life outcomes resource use patients non-operatively cast versus brace.MethodsUKSTAR a pragmatic, superiority, multicentre, randomised controlled...
A complementary DNA encoding an inward rectifier K+ channel (HRK1) was isolated from human hippocampus using a 392-base pair cDNA (HHCMD37) as probe.HRKl shows sequence similarity to three recently cloned inwardly rectifying potassium channels (IRK1, GIRKl, and ROMKl, 60, 42, 37%, respectively) has similar proposed topology of two membrane spanning domains that correspond the inner core structure voltage gated K' channels.When HRKl expressed in Xenopus oocytes, large currents were observed...
Knowledge of sequential relationships enables future events to be anticipated and processed efficiently. Research with the serial reaction time task (SRTT) has shown that sequence learning often occurs implicitly without effort or awareness. Here, authors report 4 experiments use a triplet-learning (TLT) investigate in young older adults. In TLT, people respond only last target event series discrete, 3-event sequences triplets. Target predictability is manipulated by varying triplet...
We sought to evaluate the surgical outcomes of repair complete atrioventricular septal defects (cAVSDs) in our institution current era. From 2000 2011, 138 patients underwent definitive cAVSD. Repair was performed using a two-patch technique 92.0% and one-patch 2.2%, ventricular component closed directly 5.8% patients. Operative mortality 1.4% (2 138). Overall (8 Follow-up 96% complete. Freedom from reoperation 84.3% (95% CI 77.1–91.5%) at 8 years. Age >6 months associated with higher rates...
Background Despite recommendations and the need to accelerate redesign of delivery models be team-based patient-centred, professional silos cultural structural barriers that inhibit working together communicating effectively still predominate in hospital setting. Aiming improve rounding, we developed, implemented evaluated Interprofessional Teamwork Innovation Model (ITIM). Methods This quality improvement (QI) study was conducted at an academic medical centre. We followed system’s QI...
Children with chronic medical conditions are at increased risk of severe influenza. Uptake influenza vaccination in children and adolescents these identified special (SRMCs) is suboptimal.To assess the effectiveness Flutext-4U, a parent short message service (SMS) reminder nudge intervention, increasing immunization SRMCs.This randomized clinical trial was conducted tertiary pediatric hospital Adelaide, South Australia, from April 15 to September 30, 2021. aged 6 months younger than 18 years...
Aims There is compelling evidence for the use of cemented hip hemiarthroplasty displaced intracapsular fractures; however, risks cement are well reported and in rare cases may be associated with haemodynamic collapse. It therefore important to improve our understanding instability, intraoperative monitoring, strategies reduce risk patients. Methods We measured arterial blood pressure using LiDCO rapid Continuous Non-invasive Arterial Pressure (CNAP) finger cuff during surgery patients...
Background Relatively few studies focus on Course-Based Undergraduate Research Experiences (CUREs) to improve retention of knowledge and enhance student research experience in the social sciences. Objective We introduced a modified, manual version Balloon Analogue Risk Task (BART), which students engaged all phases project, including development risk-taking assessment, participant recruitment, scale administration, presentation modified BART, data collection, entry analysis. Method To...
The Rouge River watershed, a highly urbanized watershed in southeast Michigan, has substantial impervious surface coverage, relatively high population density, and modified stream network (e.g., straightening burial, dams, underground retention). number of channels order decreases, increasing flooding, reducing water quality, decreasing aquatic species. This study defines, identifies, describes the progression geographic pattern urban deserts—defined as those areas within that exhibit no due...
Partial atrioventricular septal defect (pAVSD) is routinely repaired with a low mortality. However, limited data are available on the long-term follow-up of these patients. The current study was designed to determine survival and morbidity large cohort patients operated at single institution. From 1975 2012, 249 consecutive underwent pAVSD repair Royal Children's Hospital. were obtained from hospital records, correspondence cardiologists primary care physicians, patient surveys state death...
These first Australian National Standards of Care for Childhood-onset Heart Disease (CoHD Standards) have been developed to inform the healthcare requirements CoHD services and enable all patients, families carers impacted by (paediatric adult congenital heart disease [ACHD]) live their best healthiest lives. The are designed provide clarity certainty required deliver excellent, comprehensive, inclusive, equitable care across Australia carers, offer an iterative roadmap future these...
The objective of this study was to investigate the effects aging on strategic control attention and extent which relationship is mediated by working memory capacity (WMC). This also sought boundary conditions wherein age differences in selectivity may occur.Across 2 studies, value-directed remembering task used Castel colleagues (Castel, A. D., Balota, D. A., & McCabe, P. (2009). Memory efficiency at encoding: Impairments Alzheimer's Disease. Neuropsychology, 23, 297-306) modified include...