Simona De Angelis

ORCID: 0000-0002-3180-9967
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About
Contact & Profiles
Research Areas
  • Thyroid Disorders and Treatments
  • Diabetes and associated disorders
  • Metabolism and Genetic Disorders
  • Congenital heart defects research
  • Effects and risks of endocrine disrupting chemicals
  • Neonatal Health and Biochemistry
  • Chemical Analysis and Environmental Impact
  • Pancreatic function and diabetes
  • Pesticide Exposure and Toxicity
  • Human Health and Disease
  • Scoliosis diagnosis and treatment
  • Congenital Heart Disease Studies
  • Toxic Organic Pollutants Impact
  • Musculoskeletal pain and rehabilitation
  • Thyroid Cancer Diagnosis and Treatment
  • Neonatal Respiratory Health Research
  • Gout, Hyperuricemia, Uric Acid
  • Case Reports on Hematomas
  • 3D Printing in Biomedical Research
  • Dye analysis and toxicity
  • Agriculture Sustainability and Environmental Impact
  • Algal biology and biofuel production
  • Aluminum toxicity and tolerance in plants and animals
  • Pregnancy and Medication Impact
  • Psychosomatic Disorders and Their Treatments

Istituto Superiore di Sanità
1992-2022

Policlinico Umberto I
2016

Sapienza University of Rome
2005-2016

Brazilian Agricultural Research Corporation
2012

Institute of Cell Biology and Neurobiology
2008

University of Rome Tor Vergata
2007

Pathological Society
2000

University of Turin
1988

In the last decade a high frequency of other congenital anomalies has been reported in infants with hypothyroidism (CH) detected by neonatal screening. present study occurrence additional malformations (CM) population CH Italy between 1991 and 1998 (n = 1420) was investigated. all centers charge screening, treatment, follow-up adhere to Italian National Registry CH. this prevalence CM (8.4%), more than 4-fold higher that (1–2%), found infants. Cardiac represented most frequent associated CH,...

10.1210/jcem.87.2.8235 article EN The Journal of Clinical Endocrinology & Metabolism 2002-02-01

Organophosphorus insecticides, as Chlorpyrifos (CPF), are widely used in agriculture and against household pests; these compounds receive an increasing consideration potential endocrine disrupters. The aim of the present study was to examine short- long-term effects CPF on thyroid adrenal glands CD1 mice following exposure at dose levels not inducing brain acetyl cholinesterase (AchE) inhibition, during gestational and/or postnatal vulnerable phases. Pregnant dams were treated with 0, 3, 6...

10.1093/toxsci/kfp017 article EN Toxicological Sciences 2009-02-03

Purpose: To determine the efficacy of Feldenkrais method for relieving pain in patients with chronic low back (CLBP) and improvement interoceptive awareness.Method: This study was designed as a single-blind randomized controlled trial. Fifty-three diagnosis CLBP at least 3 months were randomly allocated to (mean age 61.21 ± 11.53 years) or Back School group 60.70 11.72 years). Pain assessed using visual analog scale (VAS) McGill Questionnaire (MPQ), disability evaluated Waddel Disability...

10.1080/09638288.2016.1175035 article EN Disability and Rehabilitation 2016-05-23

In Italy, the surveillance of congenital hypothyroidism (CH) is performed by Italian National Registry Infants with CH (INRICH). Up to now, about 3600 infants are recorded in INRICH, and a high number twins included.Our objective was estimate risk multiple single deliveries compare neonatal features from general population.The population INRICH 1989-2000 investigated.A more than 3-fold higher frequency found population, for first time, it possible incidence (10.1 10,000) (3.2 10,000 live...

10.1210/jc.2007-0238 article EN The Journal of Clinical Endocrinology & Metabolism 2007-05-09

Abstract Background Thyroid autoantibodies (ThyAb) and subclinical hypothyroidism occur more frequently in pregnant women with insulin-dependent diabetes mellitus than healthy women. Few studies have investigated the presence of ThyAb gestational (GDM), no significant association between pregnancy thyroid function has been reported. Objective To assess biochemical profile estimate prevalence a group at increased risk GDM due to family personal factors, investigate relationship positive...

10.1530/eje.0.1430741 article EN European Journal of Endocrinology 2000-12-01

Newborn screening program for congenital hypothyroidism (CH) adopting rescreening in at-risk neonates.To estimate the concordance rate CH twin pairs discordant at first screening; to verify whether long-term follow-up of healthy cotwins belonging may be useful diagnose thyroid hypofunction during development; evaluate importance genetic and environmental influences on liability permanent transient CH.Forty-seven were investigated. Proband was defined as pair with a positive test confirmed...

10.1210/jc.2019-00900 article EN The Journal of Clinical Endocrinology & Metabolism 2019-07-09

Background: The frequency of overweight (OW) and obese (OB) children has increased worldwide, particularly in economically developed countries. No studies have been conducted to verify whether the increasing OW obesity schoolchildren may affect evaluation iodine nutritional status populations. aim this study was urinary concentration (UIC), thyroid volume (TV), hypoechoic pattern be affected by body mass index (BMI) schoolchildren. Methods: included (aged 11-13 years) were a part recruited...

10.1089/thy.2020.0189 article EN Thyroid 2020-12-01

Abstract Context Analysis of a 2-screen program for congenital hypothyroidism (CH) was performed using differential dried-blood spot thyrotropin (bTSH) cutoffs 10 mU/L at first screening (all infants) and 5 second (selected infants). Objectives This work aimed to characterize CH infants identified by the compare with bTSH 5.0 9.9 or greater on screening. Design Patients Maternal neonatal clinical features were retrospectively analyzed 119 babies detected screen in Lombardy region Italy, 2007...

10.1210/clinem/dgaa789 article EN The Journal of Clinical Endocrinology & Metabolism 2020-10-30

The purpose of this pilot study was to determine the efficacy an extremely low-frequency magnetic field (ELF-MF) in decreasing chronic pain fibromyalgia (FM) patients.Thirty-seven females were recruited and randomized into two groups: one group first exposed systemic ELF-MF therapy (100 microtesla, 1 80 Hz) then sham therapy, other received opposite sequence intervention.Pain, FM-related symptoms, ability perform daily tasks measured using Visual Analog Scale, Fibromyalgia Impact...

10.1682/jrrd.2015.04.0061 article EN The Journal of Rehabilitation Research and Development 2016-01-01

Abstract Context In 2005, a nationwide program of iodine prophylaxis on voluntary basis was implemented in Italy by law. However, recent data status are lacking. Objective The aim this study to evaluate efficiency, effectiveness, and possible adverse effects (increased occurrence thyroid autoimmunity hyperthyroidism) the Italian program. Methods From 2015 2019, survey performed. use iodized salt evaluated sample 164 593 adults 998 school canteens. A 4233 schoolchildren (aged 11-13 years)...

10.1210/clinem/dgad593 article EN cc-by-nc-nd The Journal of Clinical Endocrinology & Metabolism 2023-10-11

Postpartum thyroiditis (PPT) is characterized by a rapid evolution and recovery of euthyroidism. Therefore, it can represent good model to study early cytokine fluctuations in autoimmune thyroid diseases. TGFβ1 an immunosuppressive cytokine, as inhibits T B cell proliferation, natural killer cytotoxic activity, the generation cytotoxicity. The aim this was assess serum concentrations during pregnancy possible different phases PPT. Thyroid biochemical pattern, antithyroid autoantibodies...

10.1210/jc.2002-020990 article EN The Journal of Clinical Endocrinology & Metabolism 2003-03-01

BACKGROUND: The perception of body image and the deformity trunk in patients with adolescent idiopathic scoliosis (AIS) are a silver lining that has yet to be discussed relevant literature during brace rehabilitation treatment. OBJECTIVE: To determine whether how use br ace changes AIS by drawing test. METHODS: We observed 32 subjects from our Rehabilitation outpatient clinic divided them into treatment (BG-16 subjects) non-brace (CG-16 subjects). Trunk quality life were evaluated using...

10.3233/bmr-160733 article EN Journal of Back and Musculoskeletal Rehabilitation 2016-07-05

Recent data show that regulatory cells with transforming growth factor (TGF)-β1-dependent activity are able to restore self-tolerance in overtly diabetic non-obese (NOD) mice. Thus, TGF-β1 seems have a relevant role protection from autoimmune diabetes. Our aim was investigate the possible significance of serum measurement natural history diabetes NOD mice, as well children positive for at least one islet-related antibody. Serum (both total and active) measured by enzyme-linked immunosorbent...

10.1111/j.1365-2249.2010.04253.x article EN Clinical & Experimental Immunology 2010-09-01

Autoimmune phenomena, especially occurrence of non organ-specific autoantibodies, are common in congenitally acquired HIV infection, mostly the symptomatic stages disease. Anti-thyroid autoantibodies detected adult patients represent only type reported infection. As far as we know, these has not been observed infected children. In this study thyroid biochemical pattern and possible anti-thyroid were investigated 40 vertically infected, 18 seroreverted 22 healthy 34% children showed...

10.1515/jpem.1998.11.6.745 article EN Journal of Pediatric Endocrinology and Metabolism 1998-01-01
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