Ingolf Askevold
A5010581011- Trauma and Emergency Care Studies
- Abdominal Trauma and Injuries
- Renal Transplantation Outcomes and Treatments
- Transplantation: Methods and Outcomes
- Esophageal and GI Pathology
- COVID-19 and healthcare impacts
- Pelvic and Acetabular Injuries
- Appendicitis Diagnosis and Management
- Artificial Intelligence in Healthcare and Education
- Medical Malpractice and Liability Issues
- Intestinal Malrotation and Obstruction Disorders
- Hernia repair and management
- Esophageal Cancer Research and Treatment
- Amoebic Infections and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pancreatitis Pathology and Treatment
- Gastrointestinal disorders and treatments
- Palliative Care and End-of-Life Issues
- Gastroesophageal reflux and treatments
- Anorectal Disease Treatments and Outcomes
- Nutrition and Health in Aging
- Minimally Invasive Surgical Techniques
- Inflammasome and immune disorders
- Simulation-Based Education in Healthcare
- Optimism, Hope, and Well-being
Justus-Liebig-Universität Gießen
2017-2025
Universitätsklinikum Gießen und Marburg
2014-2023
Abstract Background The SARS-CoV-2 pandemic is a major challenge for health care services worldwide. It’s impact on oncologic therapies and elective surgery has been described recently, the literature provides guidelines regarding appropriate patient treatment during pandemic. However, of emergency poorly investigated up to now. Methods A 17-item web survey had distributed surgeons in June 2020 around world, investigating patients septic diseases both requiring time-to-intervention routine,...
Rationale: Although type II alveolar epithelial cells (AEC2s) are chronically injured in idiopathic pulmonary fibrosis (IPF), they contribute to regeneration IPF. Objectives: We hypothesized that Notch signaling may AEC2 proliferation, dedifferentiation characterized by loss of surfactant processing machinery, and lung Methods: applied microarray analysis, kinome profiling, flow cytometry, immunofluorescence western blotting, quantitative PCR, proliferation surface activity analysis study...
Artificial intelligence (AI) is gaining traction in medicine and surgery. AI-based applications can offer tools to examine high-volume data inform predictive analytics that supports complex decision-making processes. Time-sensitive trauma emergency contexts are often challenging. The study aims investigate surgeons' knowledge perception of using clinical
Emergency surgery represents a unique context. Trauma teams are often multidisciplinary and need to operate under extreme stress time constraints, sometimes with no awareness of the trauma's causes or patient's personal clinical information. In this perspective, dynamics how trauma function is fundamental ensuring best performance outcomes.An online survey was conducted among World Society Surgery members in early 2021. 402 fully filled questionnaires on topics knowledge translation tools,...
Chronic lung allograft dysfunction (CLAD) after transplantation is a common complication with poor prognosis. We assessed the utility of quantitative computed tomography (CT) for diagnosis, prediction, and discrimination CLAD phenotypes. retrospectively analyzed routine inspiratory expiratory CT scans from 78 patients at different time points transplantation. Mean density (MLD), parametric response mapping (PRM), percentage air trapping, airway wall morphology parameters were calculated...
Blood levels of the acute phase reactant C-reactive protein (CRP) are frequently measured as a clinical marker for inflammation, but biological functions CRP still controversial. is phosphocholine (PC)-binding pentraxin, mainly produced in liver response to elevated interleukin-1β (IL-1β) and IL-1β-dependent cytokine IL-6. While both cytokines play important roles host defense, excessive systemic IL-1β can cause life-threatening diseases such trauma-associated inflammation. We hypothesized...
The SARS-CoV-2 pandemic is still ongoing and a major challenge for health care services worldwide. In the first WSES COVID-19 emergency surgery survey, strong negative impact on (ES) had been described already early in situation. However, knowledge limited about current effects of patient flow through rooms, daily routine decision making ES as well their changes over time during last two years. This second survey investigates course pandemic.A web distributed to medical specialists four-week...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes disease 2019 (COVID-19) has become a global health problem with pandemic character. Lung transplant recipients may be particularly at risk due to the high degree of immunosuppression and lung being organ primarily affected by COVID-19. We describe 16-year-old male 64-year-old female recently transplanted patients COVID-19 during inpatient rehabilitation. Both were receiving triple immunosuppressive therapy had no signs...
Abstract Background Shared decision-making (SDM) between clinicians and patients is one of the pillars modern patient-centric philosophy care. This study aims to explore SDM in discipline trauma emergency surgery, investigating its interpretation as well barriers facilitators for implementation among surgeons. Methods Grounding on literature topics understanding, barriers, a survey was created by multidisciplinary committee endorsed World Society Emergency Surgery (WSES). The sent all 917...
Morgagni-Larrey congenital diaphragmatic hernia (MLH) is rare in adult patients and surgery performed infrequently. The evidence regarding the most beneficial treatment modality low. Nevertheless, with increasing experience minimally-invasive surgery, literature proves laparoscopic approach as being safely feasible. However, knowledge on disease well options are based single surgeon's experiences small case series literature.Retrospective single-center analysis (≥ 18 years) MLH from 01/2003...
To reduce the shortage of organs for transplantation by expanding organ selection criteria as a means to increase pool potential lung donors. In this study, we sought investigate impact using lungs from very old donors aged >70 years on outcomes after transplantation. Between January 2010 and November 2016, 96 patients with end-stage disease underwent in our centres. Lung were divided into 3 groups according age (donor <60 years, 60–69 ≥70 years). We examined effect donor various short-...
Abstract Background Investigating the context of trauma and acute care surgery, article aims at understanding factors that can enhance some ethical aspects, namely importance patient consent, perceptiveness role leader, perceived ethics as an educational subject. Methods The employs international questionnaire promoted by World Society Emergency Surgery. Results Through analysis 402 fully filled questionnaires surgeons from 72 different countries, three main topics are investigated through...
Abstract Perianal abscesses are frequent diseases in general surgery. Principles of standard patient care surgical drainage with exploration and concomitant treatment fistula. Antiinfective therapy is frequently applied cases severe local disease perianal sepsis. However, the role microbiologic testing purulence from disputed knowledge concerning bacteriology bacterial resistances very limited. A retrospective cohort study was performed consecutive patients (≥ 12 years age) a tertiary...
Abstract Purpose The association between sarcopenia of kidney transplant recipients and outcome after transplantation (KT) has not yet been fully understood is still considered controversial. aim our study was to analyze the impact pre-transplant on graft function, postoperative complication rates, survival patients renal transplantation. Methods In this retrospective single-center study, all who underwent KT (01/2013–12/2017) were included. Demographic data, rejection delayed patient rates...
Abstract Background Association of cognitive impairment with chronic kidney disease has been reported over the last decade. Individuals show better performance after transplantation than individuals on dialysis but are more likely to be affected by age-matched comparison groups. Better knowledge prevalence as well course and profile is important for design future studies assessing clinical impact developing management strategies. The goal our study examine extent before derive a distinct...
Abstract Background In contrast to adults, the situation for pediatric trauma care from an international point of view and global management severely injured children remain rather unclear. The current study investigates structural in centers different levels as well experiences with around world. Methods A web-survey had been distributed mailing list World Society Emergency Surgery 10/2021–03/2022, investigating characteristics respondents affiliated hospitals, case-load patients,...
Abstract Purpose Trans-hiatal herniation after esophago-gastric surgery is a potentially severe complication due to the risk of bowel incarceration and cardiac or respiratory complaints. However, measures for prevention treatment options are based on single surgeon´s experiences small case series in literature. Methods Retrospective single-center analysis patients who underwent surgical repair trans-hiatal hernia following gastrectomy esophagectomy from 01/2003 07/2020 regarding clinical...
Human cytomegalovirus (HCMV) infections and reactivations are common after lung transplantation associated with the development of bronchiolitis obliterans syndrome. Against this background, temporary HCMV prophylaxis is an established standard regimen in most centers. However, optimal duration unclear. We conducted a retrospective two-center study to determine efficacy indefinite lifelong oral valganciclovir cohort 133 transplant recipients mean follow-up time approximately 5 years. During...
Patients undergoing esophageal cancer surgery are at high risk of developing severe pulmonary complications. Beneficial effects minimally invasive esophagectomy had been discussed recently, but the incidence perioperative respiratory impairment remains unclear. This is a retrospective single-center cohort study patients, who underwent open (OE) or laparoscopically assisted, hybrid abdomino-thoracic (LAE) for regarding (PaO2/FiO2 ratio (P/FR) < 300 mmHg) and pneumonia. No differences were...
The use of robotic systems in bariatric surgery has constantly increased over the last years. However, beside its technical advantages morbidly obese patients conclusive role robotics and metabolic is still under controversial debate. This an analysis prospectively collected data consecutive undergoing fully Roux-en-Y gastric bypasses (TR-RYGB) during first year after implementation a program at tertiary university hospital. All were operated by previously untrained but experienced...
Resection rectopexy (RR) provides good functional results and low recurrence rates for the treatment of obstructed defecation syndrome based on rectal prolapse cul-de-sac syndrome, whereas little is known about changes in pelvic floor dynamics patient satisfaction after surgery.Within three years 26 consecutive female patients were prospectively included. Indications RR (22 laparoscopic, 3 primary open 1 converted-to-open) III° 11 15 patients. Patients' quality life (QOL), fecal behavior...
Background Cancer is one of the leading causes death worldwide, and cardiopulmonary comorbidities may further adversely affect cancer prognosis. We recently described lung cancer-associated pulmonary hypertension (PH) as a new form PH comorbidity cancer. While patients with had significantly reduced overall survival compared without PH, prevalence impact in other cancers remain unclear. Methods In this retrospective, observational cohort study, we analysed on clinical outcomes 1184 solid...
ABSTRACT Background Post‐lung transplantation (LTx) fluid accumulation can lead to dilution of serum creatinine (SCr). We hypothesized that might impact the diagnosis, staging, and outcome posttransplant acute kidney injury (AKI). Methods In this retrospective study, we analyzed data from 131 adult LTx patients at a single German lung center between 2005 2018. assessed occurrence AKI within 7 days posttransplant, both before after SCr‐adjustment for balance (FB), investigated its on...