János Hajdu
A5063551258- Advanced X-ray Imaging Techniques
- Enzyme Structure and Function
- Advanced Electron Microscopy Techniques and Applications
- X-ray Spectroscopy and Fluorescence Analysis
- Quantum and electron transport phenomena
- Laser-Plasma Interactions and Diagnostics
- Photosynthetic Processes and Mechanisms
- Hemoglobin structure and function
- Protein Structure and Dynamics
- Metal-Catalyzed Oxygenation Mechanisms
- Advancements in Semiconductor Devices and Circuit Design
- Crystallography and Radiation Phenomena
- Particle Accelerators and Free-Electron Lasers
- Mass Spectrometry Techniques and Applications
- Laser-Matter Interactions and Applications
- Biochemical and Molecular Research
- Ion-surface interactions and analysis
- Bacteriophages and microbial interactions
- Electron and X-Ray Spectroscopy Techniques
- Advanced Thermodynamics and Statistical Mechanics
- Diamond and Carbon-based Materials Research
- Laser-induced spectroscopy and plasma
- Carbohydrate Chemistry and Synthesis
- Topological Materials and Phenomena
- Atomic and Molecular Physics
Extreme Light Infrastructure Beamlines
2017-2025
Uppsala University
2015-2025
Czech Academy of Sciences, Institute of Physics
2009-2022
SLAC National Accelerator Laboratory
2005-2019
Institute of Molecular Biology and Biophysics
2019
European X-Ray Free-Electron Laser
2014-2018
Lawrence Livermore National Laboratory
2007-2017
Charles University
2017
Stanford University
2007-2012
Menlo School
2007-2012
Intense femtosecond laser excitation can produce transient states of matter that would otherwise be inaccessible to laboratory investigation. At high densities, the interatomic forces bind solids and determine many their properties substantially altered. Here, we present detailed mapping carrier densityâdependent potential bismuth approaching a solid-solid phase transition. Our experiments combine stroboscopic techniques use high-brightness linear electron acceleratorâbased x-ray source...
The motion of atoms on interatomic potential energy surfaces is fundamental to the dynamics liquids and solids. An accelerator-based source femtosecond x-ray pulses allowed us follow directly atomic displacements an optically modified landscape, leading eventually transition from crystalline solid disordered liquid. We show that, first order in time, are inertial, we place constraints shape curvature transition-state surface. Our measurements point toward analogies between this...
The following topics are dealt with: TTF/FLASH in the XFEL context, general layout of facility, accelerator, undulators for SAES and spontaneous emission, photon beamlines scientific instruments, infrastructure auxiliary systems, commissioning operation, project management organization, cost time schedule. (HSI)
We present a proof-of-concept three-dimensional reconstruction of the giant mimivirus particle from experimentally measured diffraction patterns an x-ray free-electron laser. Three-dimensional imaging requires assembly many two-dimensional into internally consistent Fourier volume. Since each is randomly oriented when exposed to pulse, relative orientations have be retrieved data alone. achieve this with modified version expand, maximize and compress algorithm validate our result using new...
We demonstrate the use of an X-ray free electron laser synchronized with optical pump to obtain diffraction snapshots from photoactivated states large membrane protein complexes in form nanocrystals flowing a liquid jet.Light-induced changes Photosystem I-Ferredoxin co-crystals were observed at time delays 5 10 µs after excitation.The result correlates microsecond kinetics transfer I ferredoxin.The undocking process that follows leads rearrangements crystals will terminally lead...
Intense femtosecond x-ray pulses from free-electron laser sources allow the imaging of individual particles in a single shot. Early experiments at Linac Coherent Light Source (LCLS) have led to rapid progress field and, so far, coherent diffractive images been recorded biological specimens, aerosols, and quantum systems with few-tens-of-nanometers resolution. In March 2014, LCLS held workshop discuss scientific technical challenges for reaching ultimate goal atomic resolution single-shot...
Abstract The new European X-ray Free-Electron Laser is the first free-electron laser capable of delivering pulses with a megahertz inter-pulse spacing, more than four orders magnitude higher previously possible. However, to date, it has been unclear whether would indeed be possible measure high-quality diffraction data at pulse repetition rates. Here, we show that structures can obtained using currently available operating conditions XFEL. We present two complete sets, one from well-known...
There exists a conspicuous gap of knowledge about the organization life at mesoscopic levels. Ultra-fast coherent diffractive imaging with X-ray free-electron lasers can probe structures relevant length scales and may reach sub-nanometer resolution on micron-sized living cells. Here we show that introduce beam aerosolised cyanobacteria into focus Linac Coherent Light Source record diffraction patterns from individual cells very low noise levels high hit ratios. We obtain two-dimensional...
Linear-accelerator-based sources will revolutionize ultrafast x-ray science due to their unprecedented brightness and short pulse duration. However, time-resolved studies at the resolution of duration are hampered by inability precisely synchronize an external laser accelerator. At Sub-Picosecond Pulse Source Stanford Linear-Accelerator Center we solved this problem measuring arrival time each high energy electron bunch with electro-optic sampling. This measurement indirectly determined...
In nanotechnology, strategies for the creation and manipulation of nanoparticles in gas phase are critically important surface modification substrate-free characterization. Recent coherent diffractive imaging with intense femtosecond X-ray pulses has verified capability single-shot nanoscale objects at suboptical resolutions beyond radiation-induced damage threshold. By intercepting electrospray-generated particles a single 15 soft-X-ray pulse, we demonstrate specimen free flight first time,...