- Advanced X-ray Imaging Techniques
- Astro and Planetary Science
- X-ray Spectroscopy and Fluorescence Analysis
- Advanced Electron Microscopy Techniques and Applications
- Planetary Science and Exploration
- Electron and X-Ray Spectroscopy Techniques
- Laser-Plasma Interactions and Diagnostics
- Enzyme Structure and Function
- Astrophysics and Star Formation Studies
- Advancements in Photolithography Techniques
- Particle Accelerators and Free-Electron Lasers
- Crystallography and Radiation Phenomena
- Nuclear Physics and Applications
- Fluid Dynamics and Heat Transfer
- Optical Coatings and Gratings
- Laser-induced spectroscopy and plasma
- Stellar, planetary, and galactic studies
- Ion-surface interactions and analysis
- Advanced X-ray and CT Imaging
- Geochemistry and Geologic Mapping
- Geological and Geochemical Analysis
- Integrated Circuits and Semiconductor Failure Analysis
- Astrophysical Phenomena and Observations
- Particle Dynamics in Fluid Flows
- Advanced Surface Polishing Techniques
Max Planck Institute for the Structure and Dynamics of Matter
2015-2025
Deutsches Elektronen-Synchrotron DESY
2016-2025
Center for Free-Electron Laser Science
2013-2025
Universität Hamburg
2013-2025
Hamburg Centre for Ultrafast Imaging
2020-2024
Hamburg University of Technology
2024
The University of Melbourne
2022
University of Minnesota
2008-2017
Australian National University
2015
Arizona State University
2003-2015
The Stardust spacecraft collected thousands of particles from comet 81P/Wild 2 and returned them to Earth for laboratory study. preliminary examination these samples shows that the nonvolatile portion is an unequilibrated assortment materials have both presolar solar system origin. contains abundance silicate grains are much larger than predictions interstellar grain models, many high-temperature minerals appear formed in inner regions nebula. Their presence a proves formation included...
Organics found in comet 81P/Wild 2 samples show a heterogeneous and unequilibrated distribution abundance composition. Some organics are similar, but not identical, to those interplanetary dust particles carbonaceous meteorites. A class of aromatic-poor organic material is also present. The rich oxygen nitrogen compared with meteoritic organics. Aromatic compounds present, the tend be relatively poorer aromatics than meteorites particles. presence deuterium nitrogen-15 excesses suggest that...
The Trypanosoma brucei cysteine protease cathepsin B (TbCatB), which is involved in host protein degradation, a promising target to develop new treatments against sleeping sickness, fatal disease caused by this protozoan parasite. structure of the mature, active form TbCatB has so far not provided sufficient information for design safe and specific drug T. brucei. By combining two recent innovations, vivo crystallization serial femtosecond crystallography, we obtained room-temperature 2.1...
We demonstrate the use of an X-ray free electron laser synchronized with optical pump to obtain diffraction snapshots from photoactivated states large membrane protein complexes in form nanocrystals flowing a liquid jet.Light-induced changes Photosystem I-Ferredoxin co-crystals were observed at time delays 5 10 µs after excitation.The result correlates microsecond kinetics transfer I ferredoxin.The undocking process that follows leads rearrangements crystals will terminally lead...
We report experimental results on x-ray diffraction of quantum-state-selected and strongly aligned ensembles the prototypical asymmetric rotor molecule 2,5-diiodobenzonitrile using Linac Coherent Light Source. The experiments demonstrate first steps toward a new approach to diffractive imaging distinct structures individual, isolated gas-phase molecules. confirm several key ingredients single experiments: abilities detect count individual scattered photons in shot data, deliver...
Abstract The new European X-ray Free-Electron Laser is the first free-electron laser capable of delivering pulses with a megahertz inter-pulse spacing, more than four orders magnitude higher previously possible. However, to date, it has been unclear whether would indeed be possible measure high-quality diffraction data at pulse repetition rates. Here, we show that structures can obtained using currently available operating conditions XFEL. We present two complete sets, one from well-known...
Commercial EUV lithographic systems require multilayers with higher reflectance and better stability than those published to date. This work represents our effort meet these specifications. Interface-engineered Mo-Si 70% 0.545-nm bandwidth at 13.5-nm wavelength 71% 0.49-nm 12.7-nm were developed. These results achieved 50 bilayers. new consist of alternating Mo Si layers separated by thin boron carbide layers. Depositing on the interfaces leads reduction in molybdenum silicide formation...
In nanotechnology, strategies for the creation and manipulation of nanoparticles in gas phase are critically important surface modification substrate-free characterization. Recent coherent diffractive imaging with intense femtosecond X-ray pulses has verified capability single-shot nanoscale objects at suboptical resolutions beyond radiation-induced damage threshold. By intercepting electrospray-generated particles a single 15 soft-X-ray pulse, we demonstrate specimen free flight first time,...
Seven particles captured by the Stardust Interstellar Dust Collector and returned to Earth for laboratory analysis have features consistent with an origin in contemporary interstellar dust stream. More than 50 spacecraft debris were also identified. The candidates are readily distinguished from impacts on basis of elemental composition and/or impact trajectory. seven candidate diverse composition, crystal structure, size. presence crystalline grains multiple iron-bearing phases, including...
X-ray free-electron lasers deliver intense femtosecond pulses that promise to yield high resolution diffraction data of nanocrystals before the destruction sample by radiation damage. Diffraction intensities lysozyme collected at Linac Coherent Light Source using 2 keV photons were used for structure determination molecular replacement and analyzed damage as a function pulse length fluence. Signatures are observed short 70 fs. Parametric scaling in conventional crystallography does not...
Infrared spectra of material captured from comet 81P/Wild 2 by the Stardust spacecraft reveal indigenous aliphatic hydrocarbons similar to those in interplanetary dust particles thought be derived comets, but with longer chain lengths than observed diffuse interstellar medium. Similarly, samples contain abundant amorphous silicates addition crystalline such as olivine and pyroxene. The presence Wild is consistent mixing solar system matter. No hydrous or carbonate minerals were detected,...