A5038803466- Geotechnical Engineering and Analysis
- Rock Mechanics and Modeling
- Education and Learning Interventions
- Tunneling and Rock Mechanics
- Geotechnical Engineering and Underground Structures
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Agriculture, Soil, Plant Science
- Semiconductor materials and devices
- Educational Research and Pedagogy
- Advancements in Semiconductor Devices and Circuit Design
- Landslides and related hazards
- Integrated Circuits and Semiconductor Failure Analysis
- Tendon Structure and Treatment
- Online and Blended Learning
- Impact of Technology on Adolescents
- Educational Systems and Policies
- Civil and Geotechnical Engineering Research
- Korean Urban and Social Studies
- Engineering Applied Research
- Underground infrastructure and sustainability
- Copper Interconnects and Reliability
- Nanoplatforms for cancer theranostics
- Radiomics and Machine Learning in Medical Imaging
- Orthopedic Surgery and Rehabilitation
Korea Electric Power Corporation (South Korea)
2019-2025
Norgine (United Kingdom)
2023
Soongsil University
2023
Inha University
2020-2021
Chung-Ang University
2020
Inje University
2018
Hanyang University
2013-2018
Korea Railroad Research Institute
2018
National Health Insurance Service Ilsan Hospital
2017
National Health Insurance Service
2017
Abstract This paper examines the construct of social presence and develops an instrument to measure in distance higher education. Social is regarded as important factor understand psychological emotional relations among distant learners, especially when constructivism discourse based learning are emphasised. Items initially drawn from literature were reviewed by experts relevant fields extracted through exploratory confirmatory analyses. Then correlation analysis was executed see...
Lymphovascular invasion (LVI) is one of the most important prognostic factors in gastric cancer as it indicates a higher likelihood lymph node metastasis and poorer overall outcome for patient. Despite its importance, detection LVI(+) histopathology specimens can be challenging task pathologists subtle difficult to discern. Herein, we propose deep learning-based method using H&E-stained whole-slide images. The ConViT model showed best performance terms both AUROC AURPC among...
Although rock-mass rating (RMR) and tunneling quality index (Q) systems are used in different rock engineering projects as empirical design tools, their application tunnel is widely accepted these were developed updated for this purpose specifically. This paper reviews the work conducted by various researchers since development of two with respect to only. Compared other classification systems, received international acceptance still tools due continuous updates form characterization...
The TBM disc cutter, which is the main cutting tool of tunnel boring machines (TBMs), replaced when it excessively worn during process. Disc cutters are usually monitored by workers at cutterhead chambers, and they check status wear cutters. Manual measurement occasionally results in inaccurate results. In order to overcome these limitations, real-time cutter monitoring techniques have been developed with different types sensors. This study evaluates distance performance an eddy-current...
In eukaryotic replication licensing, Cdt1 plays a key role by recruiting the MCM2-7 complex onto origin of chromosome. The C-terminal domain mouse (mCdt1C), most conserved region in Cdt1, is essential for licensing and directly interacts with complex. We have determined structures mCdt1CS (mCdt1C_small; residues 452 to 557) mCdt1CL (mCdt1C_large; 420 using X-ray crystallography solution NMR spectroscopy, respectively. While N-terminal 31 form flexible loop short helix near middle, rest...
The primary output of the rock mass rating (RMR) and tunneling quality index (Q) system is a preliminary tunnel support design, as these methods are empirically developed updated for this purpose. In study, internationally accepted design tools evaluated to improve results design. simplified improved some parameters through use equations replace discrete/lump characterization with continuous rating. Recent developments in used proposing back analysis approach calculation from span installed...
In this study, we designed near-infrared (NIR)-responsive Mn2+-doped melanin-like poly(L-DOPA) nanoparticles (MNPs), which act as multifunctional nano-platforms for cancer therapy. MNPs, exhibited favorable π-π stacking, drug loading, dual stimuli (NIR and glutathione) responsive release, photothermal photodynamic therapeutic activities, T1-positive contrast magnetic resonance imaging (MRI). First, MNPs were fabricated via KMnO4 oxidation, where the embedded Mn2+ acted a T1-weighted agent....
Empirical classification systems do not provide details of the factors that affect performance fully grouted rock bolts, as they are based on average values. Fully rock-bolt patterns during tunnel-support design a part composite support, and functions rock-mass quality tunnel span. Various bolts used in situ different environments, along with other materials static dynamic environments construction. The performances evaluated through pull-out tests follow ASTM standards. Several field were...
Rockburst is an unstable failure of a rock mass which influenced by many factors. During deep excavations, the presence nearby geological structures such as minor faults, joints, and shear zones increases likelihood rockburst occurrence. A zone has been observed in headrace tunnel Neelum Jhelum Hydropower Project, Pakistan, played important role major events project’s history. seismic event that involves release great amount energy dynamic wave radiated from source reaches excavation...
Attempts to understand the emotion have evolved from perspective of an independent cognitive system mind that interactive response involving body. This study aimed quantify and visualize relationships between different emotions bodily organ systems East Asian medicine.Term frequency-inverse document frequency (tf-idf) method was used significance Five Viscera gallbladder relative seven through classical medical text DongUiBoGam. Bodily organs corresponded were visualized using a body...
The utility tunnels used for electricity transmission are in high demand these days. literature presents many limitations the currently cutterhead drive design procedure while using a shield tunnel boring machine (TBM) excavation of relatively small diameter tunnels. In order to develop an appropriate method specially drive, experimental data obtained through operation 3560 mm TBM were this research work. For purpose, earth pressure balance (EPB) was manufactured and facility established...
Empirical systems for the classification of rock mass are used primarily preliminary support design in tunneling. When applying existing acceptable international tunnel supports high-stress environments, tunneling quality index (Q) and (RMi) that preferred over geomechanical due to stress characterization parameters incorporated into two systems. However, these not appropriate when applied a location where is jointed experiencing high stresses. This paper empirically extends application...
We have developed a novel cell stretching device (called Cell Gym) capable of applying physiologically relevant low magnitude strains to tenocytes on collagen type I coated membrane. validated our thoroughly two levels: (1) substrate strains, (2) level strains. Our strain results showed that the applied stretches were transferred cells accurately (∼90%). gene expression data mechanically stimulated (4%) expressed lower COL gene. COX2 was increased but did not reach statistical significance....
Physiological loading is essential for the maintenance of articular cartilage through regulation tissue remodeling. To correctly understand behavior chondrocytes in their native environment, cell stimulating devices and bioreactors have been developed to examine effect mechanical stimuli on chondrocytes. This study describes design validation a novel system analyzing chondrocyte deformation patterns. involves an vitro device controlled application multi-axial-loading regimes...
Three-dimensional (3D) computational aortic models have been established to reproduce diseases such as aneurysm and dissection; however, no developed study diabetes mellitus (DM). To characterize biomechanical properties of the human aorta with DM, reconstructed CT images were converted into DICOM format, imported 3D segmentation using Mimics software. This resulted in a reconstruction complete aorta, including three branches. We applied pulsatile blood pressure waveform for ascending...
In this study, we designed bisphosphonate-conjugated polyanionic hyaluronic acid (HA) microbeads (MBs) for the controlled delivery of bone morphogenetic protein 2 (BMP2). MBs were prepared via photo-crosslinking bisphosphonate (alendronate)-conjugated methacrylated HA (Alen-MHA). The Alen-MHA actively absorbed cationic BMP2 up to 91.0% loading efficacy and displayed a sustained release 10 days. BMP2/Alen-MHA induced osteogenic-related genes in cellular experiments showed highly increased...
Five new transition metal coordination polymers, [Zn 3 ( bipy )( TC ) 6 ] 1 ), [Co 2 [Co( [Cd( 4 and [Cu 5 = 4,4'‐bipyridine; 3‐thiophenecarboxylate), with chain structures, were solvothermally synthesized in high yields under mild reaction conditions. While compounds , reveal peddle wheel‐like exhibit ladder‐like backbones. The organic ligand was utilized as a linker that connects each cluster consisting of the corresponding cation infinite chain. frameworks are thermally robust up to ca....
Abstract Noninvasive and precise diagnosis of hepatic fibrosis is very important for the preventive therapeutic regimen cirrhosis cancer. In this study, we fabricated T 1 contrast Mn‐porphyrin (MnTPPS 4 )/retinoic acid‐chitosan ionic‐complex nanoparticles (MRC NPs). The functional properties MRC NPs were evaluated via transmission electron microscopy (TEM) imaging, release cytotoxicity assay, hepatocyte‐specific uptake magnetic resonance (MR) imaging study. TEM images confirmed typical...