A5016348883- Nanoparticle-Based Drug Delivery
- RNA modifications and cancer
- Epigenetics and DNA Methylation
- Cancer, Hypoxia, and Metabolism
- Conducting polymers and applications
- Analytical Chemistry and Sensors
- Nanoplatforms for cancer theranostics
- Asymmetric Hydrogenation and Catalysis
- Advanced Sensor and Energy Harvesting Materials
- Cancer-related molecular mechanisms research
- Semiconductor materials and devices
- RNA Interference and Gene Delivery
- Silicon Nanostructures and Photoluminescence
- MicroRNA in disease regulation
- Cancer-related gene regulation
- Thin-Film Transistor Technologies
- Chemical Synthesis and Analysis
- Chemical Synthesis and Reactions
- Catalytic Cross-Coupling Reactions
- Electrochemical sensors and biosensors
- Covalent Organic Framework Applications
- Membrane Separation Technologies
- Curcumin's Biomedical Applications
- Sulfur-Based Synthesis Techniques
- Membrane Separation and Gas Transport
Jiangnan University
2023-2025
Duke Kunshan University
2025
Peking University International Hospital
2024
First Affiliated Hospital of Xi'an Jiaotong University
2024
Xi'an Jiaotong University
2022-2024
Peking University
2024
Shandong University of Traditional Chinese Medicine
2024
Yan'an University
2024
Xihua University
2024
Inner Health
2023
Although targeting cancer metabolism is a promising therapeutic strategy, clinical success will depend on an accurate diagnostic identification of tumor subtypes with specific metabolic requirements. Through broad metabolite profiling, we successfully identified three highly distinct in pancreatic ductal adenocarcinoma (PDAC). One subtype was defined by reduced proliferative capacity, whereas the other two (glycolytic and lipogenic) showed levels associated glycolysis, lipogenesis, redox...
Accumulating preclinical and clinical evidence implicates epithelial-mesenchymal transition (EMT) in acquired resistance to anticancer drugs; however, mechanisms by which the mesenchymal state determines drug remain unknown. To explore a potential role for altered cellular metabolism EMT associated resistance, we analyzed metabolome transcriptome of three lung cancer cell lines that were rendered resistant following experimental induction EMT. This analysis revealed metabolic rewiring during...
Salicylic acid (SA) plays an important role in plant response to abiotic stresses. This study investigated the potential of SA alleviating adverse effects chilling stress on photosynthesis and growth watermelon (Citrullus lanatus). Chilling induced simultaneous accumulation free conjugated plants, chilling-induced production was attributed phenylalanine ammonia-lyase pathway. Applying at moderate concentrations tolerance, whereas inhibition biosynthesis by L-α-aminooxy-β-phenylpropionic...
How to enhance heavy oil recovery meet the consumption is a popular issue around world, and it has attracted widespread attention. A two-dimensional visualized model was adopted study pore-scale mechanisms development effects of foam for enhancing in steam injection processes oil. Experimental images visually presented that small bubbles gather together form bigger foams, thus blocking pores throats leading fluid diversion porous media. As result, sweep efficiency improved from 46.18% 77.93%...
Triggered drug release from anti-tumor nanomedicine is an efficient approach to address the dilemma of systemic nanocarrier stability and on-demand liberation in tumor sites.
Nanoscale drug delivery platforms have been developed over the past four decades that shown promising clinical results in several types of cancer and inflammatory disorders. These nanocarriers carrying therapeutic payloads are maximizing outcomes while minimizing adverse effects. Yet one major challenges facing developers is dilemma premature versus on-demand release, which influences regiment, efficacy potential toxicity. Herein, we report on redox-sensitive polymer-drug conjugate micelles...
Long non-coding RNAs (lncRNAs) have previously been reported to be involved in cancer invasion, proliferation and apoptosis. However, the association between lncRNA, H19, esophageal (EC) has remained elusive. In present study, reverse transcription quantitative‑polymerase chain reaction revealed that expression of H19 was significantly increased associated with tumor depth metastasis 133 EC samples. Furthermore, MTT Transwell assays overexpression vitro promoted invasion cell lines, whereas...
MOF-808(Zr) with the coordinated unsaturated (CUS) Zr4+ centers was synthesized by thermal reflux method, and a series of Au/MOF-808(Zr) catalysts different Au loading percentages have been prepared impregnation–reduction method. The related X-ray diffraction, Fourier transform infrared spectroscopy, high-resolution transmission electron microscopy, photoelectron N2 adsorption–desorption, Inductively coupled plasma-mass spectrometry, NH3 temperature-programmed desorption characterizations...