Chi-Yi Chen

ORCID: 0000-0002-5438-2871
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About
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Research Areas
  • Hepatitis C virus research
  • Liver Disease Diagnosis and Treatment
  • Hepatitis B Virus Studies
  • HIV/AIDS drug development and treatment
  • Cosmology and Gravitation Theories
  • Relativity and Gravitational Theory
  • Liver Disease and Transplantation
  • Gastric Cancer Management and Outcomes
  • Computational Physics and Python Applications
  • Experimental and Theoretical Physics Studies
  • Black Holes and Theoretical Physics
  • Systemic Lupus Erythematosus Research
  • Organ Transplantation Techniques and Outcomes
  • Helicobacter pylori-related gastroenterology studies
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Pancreatic and Hepatic Oncology Research
  • Noncommutative and Quantum Gravity Theories
  • Colorectal Cancer Screening and Detection
  • Colorectal Cancer Surgical Treatments
  • Cancer-related molecular mechanisms research
  • Gastrointestinal disorders and treatments
  • Esophageal and GI Pathology
  • Economic and Social Development
  • Pulsars and Gravitational Waves Research
  • Pancreatitis Pathology and Treatment

Chia-Yi Christian Hospital
2016-2025

Tianjin First Center Hospital
2015-2024

Tianjin Medical University
2015-2024

Nankai University
2024

National Cheng Kung University Hospital
2022

Chung Shan Medical University Hospital
2019-2020

Chung Shan Medical University
2019-2020

Chinese Academy of Medical Sciences & Peking Union Medical College
2019

Chi Mei Medical Center
2016

Chia Nan University of Pharmacy and Science
2016

Background and Aims: A single-nation study reported that pretreatment HBV viral load is associated with on-treatment risk of HCC in patients who are HBeAg-positive without cirrhosis chronic hepatitis B initiating antiviral treatment. We aimed to validate the association between baseline a larger, multinational cohort. Approach Results: Using cohort from Korea, Hong Kong, Taiwan involving 7545 adult HBeAg-positive, started entecavir or tenofovir treatment ≥5.00 log 10 IU/mL, was estimated by...

10.1097/hep.0000000000000752 article EN cc-by-nc-nd Hepatology 2024-01-24

Background: Although cold snare polypectomy (CSP) is considered effective in reducing delayed postpolypectomy bleeding risk, direct evidence supporting its safety the general population remains lacking. Objective: To clarify whether CSP would reduce risk after compared with hot (HSP) population. Design: Multicenter randomized controlled study. (ClinicalTrials.gov: NCT03373136) Setting: 6 sites Taiwan, July 2018 through 2020. Participants: Participants aged 40 years or older polyps of 4 to 10...

10.7326/m22-2189 article EN Annals of Internal Medicine 2023-02-20

Chronic hepatitis C (CHC) patients who failed antiviral therapy are at increased risk for hepatocellular carcinoma (HCC). This study assessed the potential role of metformin and statins, medications diabetes mellitus (DM) hyperlipidemia (HLP), in reducing HCC among these patients. We included CHC from T-COACH therapy. tracked onset 1.5 years post-therapy by linking to Taiwan's cancer registry data 2003 2019. accounted death liver transplantation as competing risks employed Gray's cumulative...

10.3350/cmh.2024.0038 article EN cc-by-nc Clinical and Molecular Hepatology 2024-04-19

Objective Data regarding the real-world effectiveness and safety of sofosbuvir/velpatasvir (SOF/VEL) with or without low-dose ribavirin (RBV) in patients chronic hepatitis C virus (HCV) infection severe renal impairment (RI) are limited. We evaluated performance SOF/VEL RBV HCV-infected kidney disease stage 4 5. Design 191 compensated (n=181) decompensated (n=10) liver diseases receiving (400/100 mg/day) alone (200 for 12 weeks were retrospectively recruited at 15 academic centres Taiwan....

10.1136/gutjnl-2020-323569 article EN Gut 2021-01-06

Background/Aims: Despite the high efficacy of direct-acting antivirals (DAAs), approximately 1–3% hepatitis C virus (HCV) patients fail to achieve a sustained virological response. We conducted nationwide study investigate risk factors associated with DAA treatment failure. Machine-learning algorithms have been applied discriminate subjects who may respond therapy.Methods: analyzed Taiwan HCV Registry Program database explore predictors failure in patients. Fifty-five host and features were...

10.3350/cmh.2023.0287 article EN cc-by-nc Clinical and Molecular Hepatology 2023-01-01

INTRODUCTION: Concerns regarding bleeding remain in cold snare polypectomy (CSP) for small pedunculated (0-Ip) polyps. The aim of this study was to compare the risk CSP and hot (HSP) such lesions. METHODS: Data on 0-Ip colorectal polyps ≤10 mm were extracted from a large, pragmatic, randomized trial. Immediate postpolypectomy (IPPB), defined as perioperative use clip bleeding, evaluated through polyp-level analysis. Delayed (DPPB), occurring within 2 weeks postoperatively, assessed at...

10.14309/ajg.0000000000002847 article EN cc-by-nc-nd The American Journal of Gastroenterology 2024-05-09

Abstract Background Both European Association for the Study of Liver (EASL) and American Diseases Infectious Society America (AASLD-IDSA) guidelines recommend simplified hepatitis C virus (HCV) treatment with pan-genotypic sofosbuvir/velpatasvir or glecaprevir/pibrentasvir eligible patients. This observational study used real-world data to assess these regimens’ safety in patients develop an algorithm identify suitable by non-specialists. Methods 7,677 HCV-infected from Taiwan Hepatitis...

10.1007/s12072-023-10609-7 article EN cc-by Hepatology International 2024-01-21

The representations of the algebra coordinates and momenta noncommutative phase space are given. We study, as an example, harmonic oscillator in any dimension. Finally map Schrödinger equation from to commutative is obtained.

10.1142/s0217732305017421 article EN Modern Physics Letters A 2005-08-24
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