A5066260188- Ocular Surface and Contact Lens
- Allergic Rhinitis and Sensitization
- Contact Dermatitis and Allergies
- Dermatology and Skin Diseases
- Olfactory and Sensory Function Studies
- Retinal Imaging and Analysis
- Ergonomics and Musculoskeletal Disorders
- Corneal surgery and disorders
- Advancements in Transdermal Drug Delivery
- Retinal and Optic Conditions
- Visual perception and processing mechanisms
- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Trauma and Emergency Care Studies
- Ophthalmology and Visual Impairment Studies
- Skin Protection and Aging
- Radiopharmaceutical Chemistry and Applications
- Advanced Drug Delivery Systems
- Traumatic Brain Injury Research
- Medical Imaging Techniques and Applications
- Surfactants and Colloidal Systems
- Healthcare and Venom Research
- Mast cells and histamine
- Ocular Infections and Treatments
- Edible Oils Quality and Analysis
Juntendo University
2022-2024
University of Waterloo
2017-2022
York University
2015
North Shore University Hospital
1999
New York University
1999
Universiti Sains Malaysia
1993
Dry eye disease (DED) is one of the most common ocular surface diseases. Numerous patients with DED remain undiagnosed and inadequately treated, experiencing various subjective symptoms a decrease in quality life work productivity. A mobile health smartphone app, namely, DEA01, has been developed as noninvasive, noncontact, remote screening device, context an ongoing paradigm shift care system, to facilitate diagnosis DED.This study aimed evaluate capabilities DEA01 app diagnosis.In this...
Abstract Background Hay fever is a common allergic disease, with an estimated worldwide prevalence of 14.4% and variety symptoms. This study assessed the minimal clinically important difference (MCID) nasal symptom score (NSS), non‐nasal (NNSS), total symptoms (TSS) for app‐based hay‐fever monitoring. Methods MCIDs were calculated based on data from previous large‐scale, crowdsourced, cross‐sectional using AllerSearch, in‐house smartphone application. determined anchor‐based...
Probability matching is a classic theory of decision making that was first developed in models cognition. Posterior probability matching, variant which observers match their response probabilities to the posterior each being correct, used increasingly often perception. However, little known about whether consistent with vast literature on vision and hearing has within signal detection theory. Here we test using two tools from First, examine models' performance two-pass experiment, where...
Using traditional patient-reported outcomes (PROs), such as paper-based questionnaires, is cumbersome in the era of web-based medical consultation and telemedicine. Electronic PROs may reduce burden on patients if implemented widely. Considering promising reports DryEyeRhythm, our in-house mHealth smartphone app for investigating dry eye disease (DED) electronic Ocular Surface Disease Index (OSDI) should be evaluated compared to determine their equivalency.
Athletes exhibit better dynamic visual acuity (DVA) compared with nonathletes, whereas action video game players (VGPs) perform more similarly to controls despite having similar static and refractive errors. The differences in DVA between groups were not related acuity, error, or smooth pursuit gain.The purpose of the study was examine whether athletes VGPs have superior than (nonathletes, nongamers).Forty-six participants (15 athletes, 11 VGPs, 20 controls) aged 21.7 years (standard...
Rice hull ash obtained by heat treatment and acid activated followed washing was not effective as an adsorbent for carotene in palm oil contrast to that reported adsorption of soy lutein. However, unwashed acid‐activated had activity much higher than carbon silica but slightly less a commercial bleaching clay. Heat raw rice hulls at temperatures below 300°C resulted the most active after activation. Drying 200°C reduced activity. The attributed adsorbed acid. results also suggested removal...
To develop a simple extraction procedure to quantify the uptake of four topical ocular pharmaceutical drugs into contact lenses (CLs).Four silicone hydrogel (SH) CLs (balafilcon A, senofilcon lotrafilcon B, comfilcon B) and conventional (CH) (nesofilcon hilafilcon nelfilcon etafilcon A) were evaluated. The studied natamycin, moxifloxacin, timolol maleate, ketotifen fumarate. For drug incubation, three each type placed in 1 mL mg/mL drug-loading solution for 24 hours. then extracted 2...
This retrospective study aimed to determine the optimal cutoff values of Dry Eye-Related Quality-of-Life Score (DEQS) questionnaire for diagnosing dry eye disease (DED) and classifying DED severities. Participants completed DEQS questionnaire, Japanese version Ocular Surface Disease Index (J-OSDI) examinations. was diagnosed according 2016 Asia Eye Society diagnostic criteria based on symptoms (J-OSDI ≥ 13 points) tear film breakup time ≤ 5 s. Receiver operating characteristic (ROC) analysis...
Long-term ramifications of the coronavirus disease 2019 pandemic on various care-seeking characteristics patients with diabetic retinopathy remain unclear. This study aimed to identify risk factors for dropout from regular fundus examinations (RFEs) in Japan.
Background Assessing changes in quality of life patients with hay fever–related allergic conjunctivitis requires validated and clinically meaningful metrics. A minimal important difference (MCID) that can be applied to assess Domain II the Japanese Allergic Conjunctival Disease Quality Life Questionnaire (JACQLQ) a smartphone app setting has yet determined. Objective This cross-sectional observational study aimed determine MCIDs for app-based JACQLQ assessing conjunctivitis. Methods used...
To visualize the deposition of fluorescein isothiocyanate (FITC) lysozyme on daily disposable contact lenses (CLs) using a novel blink model.Three conventional hydrogel CLs (etafilcon A, omafilcon and nelfilcon A) three silicone (delefilcon senofilcon somofilcon were evaluated in study. The mounted onto model exposed to an artificial tear solution containing FITC for 2 10 hr. flow rate speed set 1 μL/min 6 blinks/min, respectively. After incubation period, 5-mm-diameter disc was punched out...
During the 5th Science, Technology, and Innovation Basic Plan, Japanese government proposed a novel societal concept -Society 5.0- that promoted healthcare system characterized by its capability to provide unintrusive, predictive, longitudinal care through integration of cyber physical space. The role Society 5.0 in managing our quality vision will become more important modern digitalized aging society, both which are known risk factors for developing dry eye. Dry eye is most common ocular...
The purpose of this study was to evaluate the uptake and release radiolabelled myristamidopropyl dimethylamine (MAP-D) on reusable daily wear contact lenses (CLs) over 7 days.Three silicone hydrogel (SH) CL materials (lotrafilcon B, balafilcon A, senofilcon A) two conventional (CH) (etafilcon omafilcon were tested. A short-term (experiment 1, N=4) a longer-term 2, N=3) conducted. In experiment CLs incubated in 2 mL phosphate buffered solution (PBS) containing 14C MAP-D (5 μg/mL) for 8 hrs....
<sec> <title>BACKGROUND</title> Assessing changes in quality of life patients with hay fever–related allergic conjunctivitis requires validated and clinically meaningful metrics. A minimal important difference (MCID) that can be applied to assess Domain II the Japanese Allergic Conjunctival Disease Quality Life Questionnaire (JACQLQ) a smartphone app setting has yet determined. </sec> <title>OBJECTIVE</title> This cross-sectional observational study aimed determine MCIDs for app-based JACQLQ...
The coronavirus disease (COVID-19) pandemic has emphasized the paucity of non-contact and non-invasive methods for objective evaluation dry eye (DED). However, robust evidence to support implementation mHealth- app-based biometrics clinical use is lacking. This study aimed evaluate reliability validity maximum blink interval (MBI) measurements using DryEyeRhythm equivalent traditional techniques in providing an accessible convenient diagnosis. In this single-center, prospective,...
Describe important patterns of neurologic injury in sports related trauma.Sports trauma represents a unique, complex pattern with potential significant impactful morbidity. An estimated 8.6 million injuries occur annually, 300,000 which result traumatic brain (TBI). The incidence other nervous system is underreported.Retrospective analysis consecutive patients who presented to an emergency department between January 1, 2015 and 2020 injury. Characterization vs non-neurological bodily injury,...