Dan Guo

ORCID: 0000-0002-5696-2415
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About
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Research Areas
  • Chinese history and philosophy
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Cardiac, Anesthesia and Surgical Outcomes
  • Venomous Animal Envenomation and Studies
  • Healthcare and Venom Research
  • COVID-19 Clinical Research Studies
  • Cancer-related molecular mechanisms research
  • Dermatological and COVID-19 studies
  • Asian Culture and Media Studies
  • Biomarkers in Disease Mechanisms
  • Obstructive Sleep Apnea Research
  • Sleep and Work-Related Fatigue
  • Non-Invasive Vital Sign Monitoring
  • Colorectal Cancer Surgical Treatments
  • Cancer Genomics and Diagnostics
  • Heme Oxygenase-1 and Carbon Monoxide
  • EEG and Brain-Computer Interfaces
  • Endoplasmic Reticulum Stress and Disease
  • Medical Research and Treatments
  • Neuroscience of respiration and sleep
  • Japanese History and Culture
  • Sleep and Wakefulness Research
  • Heavy Metal Exposure and Toxicity
  • Emotion and Mood Recognition
  • Axon Guidance and Neuronal Signaling

Henan Provincial People's Hospital
2025

Zhengzhou University
2025

Hebei North University
2024

Sichuan University
2022-2023

GenProMarkers (United States)
2022

West China Hospital of Sichuan University
2022

Affiliated Hospital of Nantong University
2021

Nantong University
2021

First Affiliated Hospital of Xi'an Jiaotong University
2018-2021

Xi'an Medical University
2020

Abstract Particulate matter 2.5 (PM2.5)‐induced pulmonary inflammation has become a public concern in recent years. In which, the activation of NLRP3/caspase‐1 pathway was closely related to inflammatory response various diseases. However, promotion effect on PM2.5‐induced remains largely unclear. Here, our data showed that PM2.5 exposure caused lung injury mice by which cell infiltration occurred and alveolar structure disorder. Meanwhile, human bronchial epithelial cells (16HBE) resulted...

10.1002/tox.23035 article EN cc-by Environmental Toxicology 2020-09-30

// Feng Yang 1 , Yizhen Chen Tao Shen Dan Guo Olga Dakhova 2 Michael M. Ittmann Chad J. Creighton 3 Yiqun Zhang Truong D. Dang David R. Rowley Department of Molecular and Cellular Biology, Baylor College Medicine, Houston, TX 77030 Pathology Immunology, Correspondence to: Yang, e-mail: fyang@bcm.edu Rowley, drowley@bcm.edu Keywords: TGF-β, AR, tumor microenvironment, prostate stroma, cancer, co-culture Received: April 24, 2014 Accepted: September 27, Published: November 06, ABSTRACT AR...

10.18632/oncotarget.2536 article EN Oncotarget 2014-10-14

Diffuse axonal injury (DAI) accounts for more than 50% of all traumatic brain injury. In response to the mechanical damage associated with DAI, abnormal proteins produced in neurons and axons, namely, β-APP p-tau, induce endoplasmic reticulum (ER) stress. Curcumin, a major component extracted from rhizome Curcuma longa, has shown potent anti-inflammatory, antioxidant, anti-infection, antitumor activity previous studies. Moreover, curcumin is an activator nuclear factor-erythroid 2-related...

10.1097/wnr.0000000000001015 article EN cc-by-nc-nd Neuroreport 2018-03-23

Spontaneous synchronization over large networks is ubiquitous in nature, ranging from inanimate to biological systems. In the human brain, neuronal and de-synchronization occur during sleep, with greatest degree of slow wave sleep (SWS). The current classification schema based on electroencephalography provides common criteria for clinicians researchers describe stages non-rapid eye movement (NREM) as well rapid (REM) sleep. These stage classifications have been convenient heuristic...

10.1038/s41598-022-11513-0 article EN cc-by Scientific Reports 2022-05-06

Abstract Background:SARS-Cov-2 infection or COVID-19 is a global pandemic. From the time of identification to till, multiple clinical symptoms and parameters have been identified by researchers various countries regions regarding diagnosis presentations COVID19 disease. In this manuscript, we investigated primary basic hematological SARS-CoV-2 among Bangladeshi patients. Methodology: We collected disease history mild moderate degree patients; biochemical on admission reports All them were...

10.21203/rs.3.rs-35016/v1 preprint EN cc-by Research Square (Research Square) 2020-06-29

Recovery from acute kidney injury (AKI) is related to long-term prognosis. This study, involving 56 patients with AKI and controls a prospective cohort undergoing coronary artery bypass grafting (CABG), investigated the prognostic performance of serum levels advanced oxidation protein products (AOPPs) for predicting non-recovered non-completely recovered AKI. AOPP increased significantly 7 days after surgery in or Increased were associated both types poor recovery Results receiver-operating...

10.3109/1354750x.2012.690103 article EN Biomarkers 2012-05-23

Abstract Background: Lung Cancer is one of the most common cancers with high degree malignancy, a devastating disease poor prognosis worldwide. prognostic prediction for patients non small-cell lung cancer (NSCLC) still challenge. Material and methods: The cohort consisted 64 consecutive NSCLC identified from June1, 2014, to June 30, 2018. Liquid biopsy samples were collected. Genomic mutation DNA was calculated by including all substitutions indels over entire somatic, coding, sequencing...

10.1097/md.0000000000020431 article EN cc-by-nc Medicine 2020-06-23

Introduction: SARS-Cov-2 infection or COVID-19 is a global pandemic. In this manuscript, we investigated the primary symptoms and basic hematological presentations of SARS-CoV-2 among Bangladeshi patients.
 Methodology: This was multicentre cross-sectional study done on patients tested positive by RT PCR in Bangladesh. Clinical features mild to moderate degree patients; biochemical admission day laboratory findings severe hospitalized were analyzed.
 Results: Bangladesh commonly...

10.3855/jidc.13692 article EN cc-by The Journal of Infection in Developing Countries 2021-03-07

10.57239/pjlss-2024-22.2.00968 article EN Pakistan Journal of Life and Social Sciences (PJLSS) 2024-01-01

An automatic sleep staging method is proposed to score wakefulness and three nonrapid eye movement (NREM) stages S1, S2 S3, based on the Empirical Mode Decomposition (EMD) algorithm. Patients with disorders were tested using this method. Good agreements between manual results achieved in terms of their Cohen's Kappa value.

10.1142/s1793536910000483 article EN Advances in Adaptive Data Analysis 2010-04-01

Mineral dust-induced gene (mdig) can accelerate cell proliferation. The aim of this study is to investigate the mechanism by which mdig regulates A549 cells were transfected with siRNA specifically targeting mdig. Cell proliferation and cycle progression measured using MTT assay analysis, respectively. Furthermore, real-time reverse transcription quantitative-polymerase chain reaction (RT-qPCR) was performed in examine expression levels related genes such as p18(INK4c), p19(INK4d),...

10.1007/s13277-015-3397-z article EN Tumor Biology 2015-04-08

Abnormal blood-brain barrier (BBB) is a common pathological feature in brain damage. In the present study, microvascular endothelial cell (BMEC) model was established to determine role of toll‑like receptor 4 (TLR4)/protein kinase Cα (PKCα)/occludin signaling pathway BBB dysfunction. Three small interfering (si)RNAs directed against PKCα were designed investigate molecular mechanisms underlying BMECs divided into groups: Control group, TAK‑242 (a TLR4 inhibitor) PKCα‑siRNA group and...

10.3892/mmr.2018.9025 article EN Molecular Medicine Reports 2018-05-16

Abstract Background Impairment of cerebral autoregulation (CA) has been observed in patients undergoing cardiopulmonary bypass (CPB), but little is known about its risks and associations with outcomes. The oximetry index (COx), which a moving linear correlation coefficient between regional oxygen saturation (rScO 2 ) mean blood pressure (MAP), may reflect CA function. When COx approaches 1, it implies that damaged, whereas the functional when value 0. objective this study was to analyze...

10.1186/s13019-023-02413-z article EN cc-by Journal of Cardiothoracic Surgery 2023-11-10

Laparoscopic gastrectomy for esophagogastric junction (EGJ) carcinoma enables the removal of at between stomach and esophagus while preserving gastric function, thereby providing patients with better treatment outcomes quality life. Nonetheless, this surgical technique also presents some challenges limitations. Therefore, three-dimensional reconstruction visualization technology (3D RVT) has been introduced into procedure, doctors more comprehensive intuitive anatomical information that...

10.4240/wjgs.v16.i5.1311 article EN World Journal of Gastrointestinal Surgery 2024-05-23

Objective: SARS-Cov-2 infection or COVID-19 is a global pandemic. From the time of identification to till, multiple clinical symptoms and parameters have been identified by researchers various countries regions regarding diagnosis presentations disease. In this manuscript, we investigated primary basic hematological SARS-CoV-2 among Bangladeshi patients. Methodology: We collected disease history mild moderate degree patients; biochemical on admission reports All them were tested positive for...

10.20944/preprints202006.0275.v1 preprint EN 2020-06-21

Pou2F3 (POU class 2 homeobox 3) is found to be ubiquitously expressed in multiple epidermal layer cells mediating proliferation. Although some POU factors exert a crucial regulation mammary epithelial (MECs), the biological function of unclear. In this study, we aimed investigate endogenous potential effects on proliferation and roles PI3K/AKT/mTOR signaling pathway MECs. We used small interfering RNA silence expression. The efficiency was confirmed by using RT-qPCR Western blot. cell...

10.1080/10495398.2020.1798974 article EN Animal Biotechnology 2020-07-30

Objective To investigate the effect of compound Kushen injection on decrease radiation-induced lung injury and improving quality life for patients with cancer during radiotherapy.Methods 229 who meet required criteria were separated randomly into two groups:treatment group control group.Acute was assessed after applying 0,2 3 months among these patients.Kamofsky before treatment.Results The incidences level 0,1,2 acute 49.53 % (53/107),42.06 (45/107),7.48 (8/107) 0.93 (1/107) respectively...

10.3760/cma.j.issn.1006-9801.2013.09.011 article EN 肿瘤研究与临床 2013-09-28

Abstract Backgroundː Impairment of cerebral autoregulation (CA) has been observed in patients undergoing cardiopulmonary bypass (CPB), but little is known about its risks and associations with outcomes. The objective this study was to analyze the incidence impaired CA, based on oximetry index (COx), total aortic arch replacement CPB moderate hypothermic circulatory arrest (MHCA). We also evaluated association between CA patient outcomes.Methodsː One hundred fifteen four adult who underwent...

10.21203/rs.3.rs-1407691/v1 preprint EN cc-by Research Square (Research Square) 2022-03-11
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