A5044508436- Multiple Myeloma Research and Treatments
- Bacterial Identification and Susceptibility Testing
- Acute Lymphoblastic Leukemia research
- Childhood Cancer Survivors' Quality of Life
- Viral gastroenteritis research and epidemiology
- Acute Myeloid Leukemia Research
- Clostridium difficile and Clostridium perfringens research
- Neuroendocrine Tumor Research Advances
- IgG4-Related and Inflammatory Diseases
- Urinary Tract Infections Management
- Gastrointestinal disorders and treatments
- Chronic Myeloid Leukemia Treatments
- Erythrocyte Function and Pathophysiology
- Antifungal resistance and susceptibility
- Urologic and reproductive health conditions
- SARS-CoV-2 and COVID-19 Research
- Microscopic Colitis
- Blood disorders and treatments
- Peptidase Inhibition and Analysis
- Antibiotic Resistance in Bacteria
- Cancer therapeutics and mechanisms
- Protein Degradation and Inhibitors
- Microbial infections and disease research
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Effects of Exercise
St. Vincent's Hospital
2022-2025
Ulsan College
2023
Asan Medical Center
2023
University of Ulsan
2023
Seoul St. Mary's Hospital
2017-2022
Catholic University of Korea
2017-2022
Background: CD71+ erythroid cells (CECs) play a complex immunoregulatory role. Methods: Flow cytometry was used to assess CECs in 84 individuals, from preterm infants adults, divided into 5 age groups, 12 under 6 months, 16 young children (6 months-5 years), 24 (6-10 22 adolescents (11-19 and 10 adults (≥20 years). Results: are universally present at very low frequencies, except individuals younger than months (P < 0.001). Although tended have higher median full-term infants, this difference...
Infectious diarrhea is a global pediatric health concern; therefore, rapid and accurate detection of enteropathogens vital. We evaluated the BioFire® FilmArray® Gastrointestinal (GI) Panel with that comparator laboratory tests. Stool samples patients were prospectively collected tested. As method for bacteria, culture, conventional PCR diarrheagenic E. coli, Allplex GI-Bacteria(I) Assay For discrepancy analysis, BD MAX Enteric Bacterial was used. virus, Virus immunochromatography used...
Conventional methods for etiologic diagnoses of acute gastroenteritis (AGE) are time consuming and have low positive yield leading to limited clinical value. This study aimed investigate quality improvements in patient management, antibiotic stewardship, in-hospital infection transmission prevention using BioFire® FilmArray® Gastrointestinal Panel (GI Panel) children with diarrhea. was a prospective recruiting < 19 years old new onset diarrhea during the period, matched historical cohort...
Enterococcus faecium, especially vancomycin-resistant E. faecium (VREfm), is a major concern for patients with hematologic diseases. Exposure to antibiotics including fluoroquinolone, which used as routine prophylaxis (MH) diseases, has been reported be risk factor infection eneterocci. We compared the characteristics of isolates according their vancomycin susceptibility and patient group (MH vs non-MH patients).A total 120 bacteremic (84 from MH 36 patients) were collected consecutively,...
Automated urine sediment analysis has been developed to address the limitations of microscopic examination dysmorphic red blood cells (RBCs). We evaluated urinary RBC distribution (URD) parameter a recently launched automated flow cytometry analyzer, UF-5000 (Sysmex, Kobe, Japan), differentiate glomerular hematuria (GH) from non-GH (NGH).Samples submitted for patients with (>20 RBCs/μL) were divided into derivation (N=156; 101 GH, 55 NGH) and validation cohorts (N=107; 60 47 NGH). The...
Recent advances in genetic analysis have led to the discovery of novel subtypes precursor B-cell acute lymphoblastic leukemia (B-ALL) with prognostic relevance. In this study, we studied a cohort pediatric B-ALL patients retrospectively determine incidence harboring subtypes, as well their outcome.B-ALL (N = 190) diagnosed single Korean hospital were included study. Patients' medical records reviewed for data on established abnormalities and outcome. CRLF2 expression was analyzed by...
Cardiac troponin (cTn) values above the 99th percentile upper reference limit (URL) indicate myocardial injury. We established URLs for three high-sensitivity cTn (hs-cTn) assays (Beckman Coulter Access hs-cTnI, Abbott STAT and Roche Elecsys hs-cTnT) using a healthy population in Korea.Each value was measured by analyzed dividing gender age.The frequency histograms of log-transformed Beckman exhibited bell-shaped distribution. The were 9.8, 17.4, 17.3 ng/L total population; 10.9/9.0,...
The detection and quantification of hepatitis B virus (HBV) DNA plays an important role in diagnosing monitoring HBV infection as well assessing the therapeutic response. We compared analytical performance a random access, fully automated assay-DxN VERIS Molecular Diagnostics System (Beckman Coulter, Brea, CA, USA)-with that Abbott RealTime assay (Abbott Laboratories, Des Plaines, IL, USA). between-day precision ranged from 0.92% (mean 4.68 log IU/mL) to 4.15% 2.09 for pooled sera patients....
Summary Inherited bone marrow failure syndromes (IBMFS) pose significant diagnostic challenges due to overlapping symptoms and variable expressivity, despite evolving genomic insights. The study aimed elucidate the landscape among 130 Korean patients with IBMFS. We conducted targeted next‐generation sequencing (NGS) clinical exome (CES) across cohort, complemented by whole genome (WGS) chromosomal microarray (CMA) in 12 47 cases, respectively, negative initial results. Notably, 50% ( n = 65)...
Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated fibroinflammatory condition with unique histopathological features that can affect most organs, making diagnosis challenging. This study characterized detailed laboratory characteristics of IgG4-RD. Baseline clinical and 33 patients IgG4-RD were reviewed, including serum IgG4 concentrations, free light chains (sFLCs), IgGĸ- IgGλ-heavy/light (HLCs), capillary protein electrophoresis (SPE), immunofixation (IFE) subclass. The...
Clonal hematopoiesis (CH) is associated with somatic mutations of the hematopoietic stem cells responsible for red blood cell formation. The incidence CH increases age and negative environmental factors. It particularly common in patients on chemotherapy, a greater than 10-fold increased risk hematological malignancy. also cardiovascular disease. Despite recent advances molecular genetic research, clinical translational aspects disease require more attention. However, as data accumulate,...