Jun Chen

ORCID: 0000-0002-6317-4281
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About
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Research Areas
  • Microbial Metabolic Engineering and Bioproduction
  • Enzyme Catalysis and Immobilization
  • Microbial Natural Products and Biosynthesis
  • Biofuel production and bioconversion
  • Plant biochemistry and biosynthesis
  • Metabolomics and Mass Spectrometry Studies
  • Marine Sponges and Natural Products
  • Analytical Chemistry and Chromatography
  • Genomics and Phylogenetic Studies
  • Quantum Chromodynamics and Particle Interactions
  • Topic Modeling
  • Recommender Systems and Techniques
  • Wastewater Treatment and Nitrogen Removal
  • Pharmacological Effects of Natural Compounds
  • Analytical Methods in Pharmaceuticals
  • High-Energy Particle Collisions Research
  • Gout, Hyperuricemia, Uric Acid
  • Odor and Emission Control Technologies
  • Industrial Gas Emission Control
  • Genomics, phytochemicals, and oxidative stress
  • Fungal Biology and Applications
  • Image Retrieval and Classification Techniques
  • Particle physics theoretical and experimental studies
  • Heat shock proteins research
  • Traditional Chinese Medicine Analysis

Abilene Christian University
2024

Xiamen University
2023-2024

Xiamen University of Technology
2023-2024

East China University of Science and Technology
2012-2024

Central South University
2023

Shenzhen Third People’s Hospital
2023

Southern University of Science and Technology
2023

West Anhui University
2022

Zhejiang University of Technology
2014-2020

Nankai University
2004-2020

Limonene, a monocyclic monoterpene, is known for its using as an important precursor of many flavoring, pharmaceutical, and biodiesel products. Currently, d-limonene has been produced via fractionation from essential oils or byproduct orange juice production, however, considering the increasing need limonene certain amount pesticides may exist in obtained citrus industry, some other methods should be explored to produce limonene.To construct synthetic pathway Yarrowia lipolytica, two genes...

10.1186/s13068-016-0626-7 article EN cc-by Biotechnology for Biofuels 2016-10-11

Abstract Atomic nuclei are self-organized, many-body quantum systems bound by strong nuclear forces within femtometre-scale space. These complex manifest a variety of shapes 1–3 , traditionally explored using non-invasive spectroscopic techniques at low energies 4,5 . However, these energies, their instantaneous obscured long-timescale fluctuations, making direct observation challenging. Here we introduce the collective-flow-assisted shape-imaging method, which images global shape colliding...

10.1038/s41586-024-08097-2 article EN cc-by Nature 2024-11-06

Yarrowia lipolytica is widely studied as a non-conventional model yeast owing to the high level of lipid accumulation. Therein, triacylglycerol (TAG) major component liposome. In order investigate TAG biosynthesis mechanism at systematic level, novel genome-scale metabolic Y. was reconstructed based on previous iYL619_PCP published by our lab and another iYali4 Kerkhoven et al. The iYL_2.0 contains 645 genes, 1083 metabolites, 1471 reactions, which validated more effective simulations...

10.1186/s40643-017-0180-6 article EN cc-by Bioresources and Bioprocessing 2017-12-01

The anaerobic bacterium Megasphaera hexanoica has great potential for caproate production through reverse β-oxidation using lactate, acetate, and butyrate as substrates. This study assessed the effect of acetate concentrations (10-50 mM) on biosynthesis, lactate oxidation, cell synthesis in M. hexanoica. At 30 mM reached 42.83 mM, with an electron efficiency 67.03 % a specific productivity 4.47 gCA·h-1·gDCW-1. Subsequent fed-batch experiments maintained continuous production, achieving 65.21...

10.1016/j.jenvman.2025.125327 article EN cc-by-nc-nd Journal of Environmental Management 2025-04-21

In our previous studies, AveI was identified as a negative regulator for avermectin biosynthesis in Streptomyces avermitilis NRRL8165, and the aveI-null mutant of NRRL8165 could produce at least 10-fold more B1a than its wild-type strain. order to explore regulatory mechanism by which aveI affects biosynthesis, this study, we performed global comparative gene expression analysis between deletion 8165DeltaI strain using NimbleGen microarrays combination with real-time reverse...

10.1111/j.1574-6968.2009.01721.x article EN FEMS Microbiology Letters 2009-07-10
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