A5100682025- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Screening and Detection
- Minimally Invasive Surgical Techniques
- Colorectal and Anal Carcinomas
- Genetic factors in colorectal cancer
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Diverticular Disease and Complications
- Orthopedic Surgery and Rehabilitation
- Surgical Simulation and Training
- Surgical site infection prevention
- Cancer Genomics and Diagnostics
- Diverse Topics in Contemporary Research
- Bone fractures and treatments
- Consumer Perception and Purchasing Behavior
- COVID-19 and healthcare impacts
- Diverse Approaches in Healthcare and Education Studies
- Anatomy and Medical Technology
- Elbow and Forearm Trauma Treatment
- Hernia repair and management
- Ear and Head Tumors
- Gastrointestinal Tumor Research and Treatment
- Teratomas and Epidermoid Cysts
- Martial Arts: Techniques, Psychology, and Education
Ajou University
2021-2025
Ajou University Hospital
2022-2025
Bucheon University
2024
Kyung Hee University Hospital at Gangdong
2015-2021
Kyung Hee University
2019
Yonsei University
2007-2017
Severance Hospital
2014-2017
Hallym University
2006-2017
Christie's
2015
American Society of Anesthesiologists
2014-2015
To review and compare clinical manifestations of risk factors for anastomotic leakage (AL) after low anterior resection rectal cancer between minimally invasive surgery (MIS) open (OS).MIS has become popular, its course is different from OS. Many studies have reported on the oncologic influence AL. However, few directly compared AL MIS OS.From January 2004 to December 2012, a total 1704 consecutive patients who underwent elective with colorectal anastomosis were eligible. The variables...
As robotic surgery was developed with ergonomic designs, there are expectations that the technical advantages of can shorten learning curve. However, is no comparative study, so far, to evaluate curve between and laparoscopic rectal cancer surgeries. Therefore, aim this study compare low anterior resection (LAR) LAR for cancer. Patients who underwent or by a single surgeon were compared retrospectively (robot n = 89 vs laparoscopy 89). Cumulative sum (CUSUM) used The patients divided into...
Although the total cost of robotic surgery (RS) is known to be higher than that laparoscopic (LS), cost-effectiveness RS has not yet been verified. The aim study clarify compared with LS for rectal cancer. From January 2007 through December 2011, 311 and 560 patients underwent totally conventional cancer, respectively. A propensity score-matching analysis was performed a ratio 1:1 reduce possibility selection bias. Costs perioperative short-term outcomes in both groups were compared....
Peritoneal carcinomatosis (PC) is a common and devastating manifestation of colon cancer refractory to conventional anticancer therapeutics. During the peritoneal dissemination cancer, immunity nullified by various mechanisms immune evasion. Here, we employed armed oncolytic vaccinia virus mJX-594 (JX) rejuvenate antitumor responses in treatment PC.PC model MC38 was generated intraperitoneally treated with JX and/or anti-programmed cell death protein 1 (PD-1) antibody. The tumor burden,...
Objective: To compare short-term perioperative outcomes of single-port laparoscopic surgery (SPLS) and multiport (MPLS) for colon cancer. Summary Background Data: Although many studies reported short- long-term SPLS cancer compared with MPLS, few have results randomized controlled trials. Methods: This was a multicenter, prospective, trial noninferiority design. It conducted between August 2011 June 2017 at 7 sites in Korea. A total 388 adults (aged 19–85 yrs) clinical stage I, II, or III...
Approximately 20 % of all patients with colorectal cancer are diagnosed as having Stage IV cancer; 80 these present unresectable metastatic lesions. It is controversial whether chemotherapy or without primary tumor resection (PTR) effective for the treatment metastasis. Primary could prevent tumor-related complications such intestinal obstruction, perforation, bleeding, fistula. Moreover, it may be associated an increase in overall survival. However, surgery delays use systemic and affects...
Abstract Background Perforated peptic ulcer (PPU) is a common emergency condition requiring surgery using laparoscopy or open repair of the perforated site. The aim this study was to assess role laparoscopic (LS) based on safety and efficacy for PPU. Methods Medical records consecutive patients who underwent LS (OS) PPU at five hospitals between January 2009 December 2019 were retrospectively reviewed. After propensity score matching, short-term perioperative outcomes compared OS in selected...
The spread of COVID-19 has led to numerous hospitals prioritizing case management and delays in diagnosis treatment. Consequently, many cancer patients have developed life-threatening complications during the pandemic. aim this study was investigate impact pandemic on colorectal (CRC), including its clinical pathologic characteristics. This multicenter cohort performed at six institutions Korea included a total 3871 with CRC treated between March 2019 February 2021. After exclusion 211 who...
Background The aim of this study was to compare the outcomes in colorectal cancer (CRC) patients with synchronous unresectable metastases who received either primary tumor resection (PTR) or chemotherapy as first treatment and investigate clinical course asymptomatic treatment. Methods We retrospectively analyzed 324 CRC metastases. Overall survival (OS) for two groups (upfront PTR group [n = 72] vs. upfront 252]). Surgical morbidity mortality were recorded. In chemotherapy, incidences...
Renal cell carcinoma (RCC) is the most common type of kidney malignancy worldwide with Pembrolizumab and axitinib treatment (Pembro/Axi) amongst effective first-line immunotherapies for advanced RCC. However, it remains difficult to predict response early resistance. Therefore, we evaluated whether baseline serum interleukin-6 (IL-6) could be a predictive biomarker. Between November 2019 December 2021, 58 patients RCC were enrolled, administered Pembro/Axi, blood samples analyzed using flow...
Abstract Genomic alterations in tumors play a pivotal role determining their clinical trajectory and responsiveness to treatment. Targeted panel sequencing (TPS) has served as key tool over the past decade, but advancements costs bioinformatics have now made whole-genome (WGS) feasible single-assay approach for almost all cancer genomes settings. This paper reports on findings of prospective, single-center study exploring real-world utility WGS (tumor matched normal tissues) two primary...
Abstract Background Prevention and early detection of colorectal cancer (CRC) is a global priority, with many countries conducting population-based CRC screening programs. Although colonoscopy the most accurate diagnostic method for detection, adherence remains low because its invasiveness need extensive bowel preparation. Non-invasive fecal occult blood tests or immunochemical are available; however, their sensitivity relatively low. Syndecan-2 ( SDC2 ) stool-based DNA methylation marker...
The work was done to study immunogenetic peculiarities of neuroinflammatory diseases among Korean children. A total 13 children with (8 males and 5 females; mean age 4.6 +/-2.6 yr) were consecutively recruited. Geno-mic typing performed on their HLA DRB/HLA DQB genes using PCR-SSOP/SSP techniques gel immunoelectrophoresis. frequencies HLA-DR1 *15 in acute disseminated encephalomyelitis (ADEM) (31%) DQB1 *06 other (38%) significantly increased compared control subjects. HLA-DRB3 * 0202...
The purpose of this study was to assess the impact circumferential tumor location on resection margin (CRM) status and depth invasion in mid low rectal cancer.We retrospectively analyzed whole-mount slides 58 patients who underwent total mesorectal excision for cancer. rate tumor-positive CRM compared according location. In 31 patients, morphometric analyses specimens were performed measure location.Among 50% tumors anterior nonanterior. A more observed frequently than nonanterior (41.1% vs....
Few studies have examined the surgical treatment of intestinal Behçet disease. Consequently, there is currently no standard for Instead, empirical and symptom based.Our aim was to evaluate clinical course after surgery determine appropriate options disease.Medical charts patients who underwent were retrospectively reviewed.The study conducted at a tertiary referral center.Ninety-one disease between January 1995 December 2012 included in this study.Primary outcomes measured patient...
Purpose: Patients who undergo radical surgery for rectal cancer often experience low anterior resection syndrome (LARS). Symptoms of this include frequent bowel movements, gas incontinence, fecal fragmentation, and urgency. The aim study was to investigate the convergent validity, discriminative reliability Korean version LARS score questionnaire.Methods: English questionnaire translated into using forward-and-back translation method. A total 146 patients underwent answered including an...