A5100328690- Kidney Stones and Urolithiasis Treatments
- Pediatric Urology and Nephrology Studies
- Ureteral procedures and complications
- Renal and Vascular Pathologies
- Urinary Tract Infections Management
- Urological Disorders and Treatments
- Renal cell carcinoma treatment
- Renal function and acid-base balance
- Porphyrin Metabolism and Disorders
- Sepsis Diagnosis and Treatment
- Heme Oxygenase-1 and Carbon Monoxide
- Paleopathology and ancient diseases
- Prostate Cancer Diagnosis and Treatment
- Urinary Bladder and Prostate Research
- Prostate Cancer Treatment and Research
- Photonic and Optical Devices
- Connexins and lens biology
- Dermatological and Skeletal Disorders
- Acute Kidney Injury Research
- Cancer, Hypoxia, and Metabolism
- Organ Donation and Transplantation
- Kruppel-like factors research
- Complex Network Analysis Techniques
- Minimally Invasive Surgical Techniques
- Spinal Fractures and Fixation Techniques
Second Military Medical University
2014-2024
Changhai Hospital
2014-2024
Sichuan University
2022-2024
Shanghai Municipal People's Government
2024
Hubei Polytechnic University
2023-2024
Yangtze University
2023-2024
Shanghai Institute of Computing Technology
2023
XinHua Hospital
2023
Peking University
2023
Shanghai Jiao Tong University
2023
Abstract Background Kidney stones are composed of approximately 70–80% calcium oxalate. However, the exact mechanism formation oxalate kidney remains unclear. In this study, we investigated roles endoplasmic reticulum stress (ERS), reactive oxygen species (ROS), and NF-κB signalling pathway in pathogenesis oxalate-induced renal tubular epithelial cell injury its possible molecular mechanisms. Methods We established a model to evaluate by intraperitoneal injection glyoxylic acid solution into...
This study assessed the characteristics of pathogens identified in clinical isolates from patients with urinary tract infection (UTI) and their vitro sensitivity to commonly used antibiotics setting China.Multicenter was conducted between January December 2011 12 hospitals China.Urine samples were collected 356 symptomatic treated for acute uncomplicated cystitis, recurrent UTI or complicated UTI.Minimal inhibitory concentrations (MICs) measured using broth microdilution according Clinical...
To evaluate the clinical and microbiological efficacy safety of three doses 3 g fosfomycin tromethamine administered orally to treat lower urinary tract infections.This prospective, uncontrolled, open-label study was conducted in 12 medical centres China, between January December 2011. According diagnosis criteria Chinese Guidelines on Urological Infections, patients (18-70 years) with acute uncomplicated cystitis, recurrent infection or complicated received orally, at days 1, 5.Efficacy...
Acute kidney injury (AKI) occurs in half of patients with septic shock, resulting unacceptably high mortality. However, effective preventive treatments are still lacking. We hypothesized that pretreatment lipoxin A4 (LXA4), known to promote inflammation resolution, may attenuate AKI via blocking crosstalk between and cellular senescence. In this study, rats developed following cecal ligation puncture (CLP), as evidenced by a dynamic increase serum creatinine, blood urea nitrogen, urinary...
To compare the peri-operative and early renal functional outcomes of robot-assisted partial nephrectomy (RAPN) laparoscopic (LPN) for kidney tumours.A total 237 patients fulfilling selection criteria were included, whom 146 91 treated with LPN RAPN, respectively. adjust potential baseline confounders, propensity-score matching was performed. A favourable outcome defined as a warm ischaemia time (WIT) ≤20 min, negative surgical margins, no conversion, Clavien ≥3 complications postoperative...
Introduction: To investigate the thermal effect on water by a novel thulium fiber laser (TFL) designed for lithotripsy and evaluate safety of this clinical use. Materials Methods: An in vitro experimental setup was constructed. A test tube filled with saline immersed an electric bath, TFL probe were inserted into it. Saline irrigated pumped out synchronously at same speed two pumps, respectively, to maintain convection when needed. Then, continuous firing different power settings imposed 60...
Abstract Over the past three decades, there has been increasing interest in miniaturized percutaneous nephrolithotomy (mPCNL) techniques featuring smaller tracts as they offer potential solutions to mitigate complications associated with standard PCNL (sPCNL). However, despite this growing acceptance and recognition of its benefits, unresolved controversies acknowledged limitations continue impede widespread adoption due a lack consensus on optimal perioperative management strategies...
We investigated the relationship of kidney calculi with plasma free and total testosterone, androgen receptor up-regulation in kidneys men nephrolithiasis.Male patients stone healthy were included study. Blood was collected a tube containing 2% heparin morning. Total serum testosterone measured by enzyme linked immunosorbent assay. All underwent percutaneous nephrostolithotomy. At end procedure ultrasound guided puncture biopsy done to acquire tissue. Normal tissue obtained at autopsy served...
Background and Purpose: The management of urolithiasis in patients with a solitary kidney is challenging for endourologists. This study was aimed at evaluating the safety efficacy retrograde intrarenal surgery (RIRS) treatment such renal stones. Patients Methods: Between January 2010 2014, we enrolled 45 who had underwent RIRS holmium:yttrium-aluminum-garnet lithotripsy We collected data pertaining to preoperative patient characteristics, stone dimensions, postoperative outcomes. Results:...
To evaluate the clinical efficacy, safety, and cost of retrograde intrarenal surgery (RIRS) percutaneous nephrolithotomy (PCNL) in treatment for large renal stones patients with a solitary kidney.In this study, 117 kidney who had undergone PCNL or RIRS larger than 2 cm between January 2010 December 2016 were retrospectively evaluated. The patients' demographic data, characteristics, perioperative outcomes collected through review their medical records. Forty-three treated compared to 43 by...
Abstract Background The morbidity of nephrolithiasis is 2–3 times higher in males than females, suggesting that androgen plays a key role nephrolithiasis. death renal tubular epithelial cells (TECs) an important pathophysiological process contributing to the development Therefore, aim this study investigate whether directly induces TECs apoptosis and necrosis its underlying mechanisms kidney stone formation. Materials methods We compared serum testosterone level between male female healthy...