A5026027021- Viral Infections and Vectors
- Virology and Viral Diseases
- Mosquito-borne diseases and control
- Animal Disease Management and Epidemiology
- Vector-Borne Animal Diseases
- Influenza Virus Research Studies
- Plant Virus Research Studies
- Insect symbiosis and bacterial influences
- Livestock and Poultry Management
- Animal Virus Infections Studies
- Environmental Toxicology and Ecotoxicology
- Microbial Natural Products and Biosynthesis
- Light effects on plants
- Viral gastroenteritis research and epidemiology
- Photosynthetic Processes and Mechanisms
- Plant Molecular Biology Research
- Malaria Research and Control
- Zoonotic diseases and public health
- vaccines and immunoinformatics approaches
- Physiological and biochemical adaptations
- Genomics and Phylogenetic Studies
- Fungal and yeast genetics research
- Synthesis and Biological Activity
- Microbial infections and disease research
- Environmental DNA in Biodiversity Studies
Centre de Coopération Internationale en Recherche Agronomique pour le Développement
2013-2024
Animal, Santé, Territoires, Risques et Ecosystèmes
2017-2024
Université de Montpellier
2018-2024
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2011-2023
COMUE Languedoc-Roussillon Universités
2023
SUNY Downstate Health Sciences University
2023
Universidad de Extremadura
2020
Institut Agro Montpellier
2010-2015
Ourofino Saúde Animal (Brazil)
2012
Centre de Recherche et de Veille sur les Maladies Emergentes dans l’Océan Indien
2008-2011
Several Avian paramyxoviruses 1 (synonymous with Newcastle disease virus or NDV, used hereafter) classification systems have been proposed for strain identification and differentiation. These pioneered efforts; however, they were based on different approaches lacked objective criteria the differentiation of isolates. differences created discrepancies among systems, rendering discussions comparisons across studies difficult. Although a system that was by Diel co-workers in 2012, ample...
The phytochrome family of plant photoreceptors has a central role in the adaptation development to changes ambient light conditions. individual species regulate different or partly overlapping physiological responses. We generated transgenic Arabidopsis plants expressing A E:green fluorescent protein (GFP) fusion proteins assess biological intracellular compartmentation these light-regulated signaling. show that all phytochrome:GFP were imported into nuclei. Translocation nuclei was...
Abstract Infection with Usutu virus (USUV) has been recently associated neurologic disorders, such as encephalitis or meningoencephalitis, in humans. These findings indicate that USUV is a potential health threat. We report an acute human infection France putatively clinical diagnosis of idiopathic facial paralysis.
Genome segmentation is mainly thought to facilitate reassortment. Here, we show that can also allow differences in segment abundance populations of bluetongue virus (BTV). BTV has a genome consisting 10 segments, and its cycle primarily involves periodic alternation between ruminants Culicoides biting midges. We have developed reverse transcription-quantitative PCR (RT-qPCR) approach quantify each wild sampled both midges during an epizootic. Segment frequencies deviated from equimolarity...
The potential existence of a wild bird reservoir for highly pathogenic avian influenza (HPAI) has been recently questioned by the spread and persisting circulation H5N1 HPAI viruses, responsible concurrent outbreaks in migratory domestic birds over Asia, Europe, Africa. During large-scale surveillance programme Eastern Middle East, Africa, we detected viruses H5N2 subtype with (HP) viral genotype healthy two waterfowl species sampled Nigeria. We monitored survival regional movements one...
Background West Nile virus (WNV) and Usutu (USUV), two closely related flaviviruses, mainly follow an enzootic cycle involving mosquitoes birds, but also infect humans other mammals. Since 2010, their epidemiological situation may have shifted from irregular epidemics to endemicity in several European regions; this requires confirmation, as it could implications for risk assessment surveillance strategies. Aim To explore the seroprevalence animals potential of WNV USUV Southern France, given...
In Madagascar, Newcastle disease (ND) has become enzootic after the first documented epizootics in 1946, with recurrent annual outbreaks causing mortality up to 40%. Four ND viruses recently isolated Madagascar were genotypically and pathotypically characterised. By phylogenetic inference based on F HN genes, also full-genome sequence analyses, NDV Malagasy isolates form a cluster distant enough constitute new genotype hereby proposed as XI. This is presumably deriving from an ancestor close...
Newcastle disease (ND) is one of the most lethal diseases poultry worldwide. It caused by an avian paramyxovirus 1 that has high genomic diversity. In framework international surveillance program launched in 2007, several thousand samples from domestic and wild birds Africa were collected analyzed. ND viruses (NDV) detected isolated apparently healthy fowls birds. However, two thirds isolates this study classified as virulent strains NDV based on molecular analysis fusion protein...
Two genes involved in the biosynthesis of depsipeptide antibiotics pristinamycins I (PI) produced by Streptomyces pristinaespiralis were cloned and sequenced. The 1.7-kb snbA gene encodes a 3-hydroxypicolinic acid:AMP ligase, 7.7-kb snbC PI synthetase 2, responsible for incorporating L-threonine L-aminobutyric acid macrocycle. snbC, which encode two first structural enzymes synthesis, are not contiguous. Both located PI-specific transcriptional units, as disruption one or other led to...
In Streptomyces pristinaespiralis, two enzymes are necessary for conversion of pristinamycin IIB (PIIB) to IIA (PIIA), the major component (D. Thibaut, N. Ratet, D. Bisch, Faucher, L. Debussche, and F. Blanche, J. Bacteriol. 177:5199-5205, 1995); these PIIA synthase, a heterodimer composed SnaA SnaB proteins, which catalyzes oxidation PIIB PIIA, NADH:riboflavin 5'-phosphate oxidoreductase (hereafter called FMN reductase), SnaC protein, provides reduced form flavin mononucleotide reaction. By...
Heterogeneity in the transmission rates of pathogens across hosts or environments may produce disease hotspots, which are defined as specific sites, times species associations infection rate is consistently elevated. Hotspots for avian influenza virus (AIV) wild birds largely unstudied and poorly understood. A striking feature existence a unique but consistent AIV hotspot shorebirds (Charadriiformes) associated with single at location time (ruddy turnstone Arenaria interpres Delaware Bay,...
Summary Photomorphogenesis of higher plants is regulated by photoreceptors including the red/far‐red light‐absorbing phytochromes, blue‐UV/A sensing cryptochromes and as yet uncharacterized UV/B receptors. Specific phototransduction pathways that are controlled either individual or interacting mediate regulation. Phytochrome B (phyB) major red light‐sensing photoreceptor. Phototransduction mediated this light sensor has been shown to include light‐dependent nuclear import interaction phyB...
ABSTRACT A novel vip3 -related gene was identified in Bacillus thuringiensis . This is 2,406 bp long and codes for a 91-kDa protein (801 amino acids). exhibits between 61 62% similarity with Vip3A proteins designated Vip3Ba1. Vip3Ba1 has several specific features. Differences the are spread throughout sequence but more frequent C-terminal part from acid 456 onward. The regions containing two proteolytic processing sites, which highly conserved among toxins, markedly different pattern DCCEE...
Zika virus (ZIKV) and dengue (DENV) are two closely related members of the Flaviviridae family, both transmitted by mosquitoes genus Aedes, among arboviruses most at risk to human health. Burkina Faso has been facing an upsurge in DENV outbreaks since 2013. Unlike DENV, there is no serological evidence ZIKV circulation humans Faso. The main objective our study was determine seroprevalence blood donors A total 501 donor samples collected major cities country 2020 were first tested a...
Abstract Background Mosquitoes (Diptera: Culicidae) can have a significant negative impact on human health. The urbanization of natural environments and their conversion for agricultural use, as well population growth, may affect mosquito populations increase the risk emerging or re-emerging mosquito-borne diseases. We report variety number adult mosquitoes found in four with varying degrees (rural, urban, rice fields, forest) located savannah zone West Africa. Methods were collected from...
Four pap genes ( papA , papB papC papM ) were found by sequencing near to snbA a Streptomyces pristinaespiralis gene which was previously shown encode one of the pristinamycin I (PI) synthetases. Analysis homologies observed from deduced amino acid sequences suggested that these four could be involved in biosynthesis PI precursor 4‐dimethylamino‐ l ‐phenylalanine (DMPAPA). This first verified when disruption S. led − phenotype, reversed addition DMPAPA into culture medium. Further...
We have determined the 5-methylcytosine (5mC) content in high molecular weight DNA, from two dicot (tobacco and pea) monocot (wheat maize) plant species, fractionated according to base composition. The results show that proportion of 5mC genomic fractions increases linearly with their guanine + cytosine (G C) while non-methylated remains almost constant. This can be interpreted as a consequence difference mutation pressure related spontaneous deamination thymine between different...
Human encephalitis represents a medical challenge from diagnostic and therapeutic point of view. We investigated the cause 2 fatal cases unknown origin in immunocompromised patients.Untargeted metatranscriptomics was applied on brain tissue patients to search for pathogens (viruses, bacteria, fungi, or protozoans) without prior hypothesis.Umbre arbovirus, an orthobunyavirus never previously identified humans, found patients. In situ hybridization reverse transcriptase-quantitative polymerase...
Abstract Our knowledge of the diversity eukaryotic viruses has recently undergone a massive expansion. This could influence host physiology through yet unknown phenomena potential interest to fields health and food production. However, assembly processes this remain elusive in viromes terrestrial animals. situation hinders hypothesis-driven tests virome on physiology. Here, we compare taxonomic between different spatial scales mosquito Culex pipiens. is vector human pathogens worldwide. The...