- Advanced Radiotherapy Techniques
- Management of metastatic bone disease
- Radiation Dose and Imaging
- Brain Metastases and Treatment
- Spinal Fractures and Fixation Techniques
- Advances in Oncology and Radiotherapy
- Spine and Intervertebral Disc Pathology
- Economic and Financial Impacts of Cancer
- Global Cancer Incidence and Screening
- Lung Cancer Research Studies
- Electronic Health Records Systems
- Lung Cancer Treatments and Mutations
- Medical Imaging Techniques and Applications
- Prostate Cancer Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Radiation Therapy and Dosimetry
- Meningioma and schwannoma management
- Pleural and Pulmonary Diseases
- Chemotherapy-induced cardiotoxicity and mitigation
- Digital Radiography and Breast Imaging
- Biomedical Text Mining and Ontologies
- Sarcoma Diagnosis and Treatment
- Radiology practices and education
- Occupational and environmental lung diseases
The University of Texas MD Anderson Cancer Center
2014-2022
Sutter Medical Center
2022
Varian Medical Systems (Germany)
2018
Novartis (China)
2018
Anderson University - South Carolina
2017
University of California, San Diego
2009-2012
American Society for Radiation Oncology
2012
The University of Texas Southwestern Medical Center
2009
Lung cancer is the leading cause of cancer-related mortality in United States and worldwide. As systemic therapies improve, patients with lung live longer thus are at increased risk for brain metastases. Understanding how prognosis varies across this heterogeneous patient population essential to individualize care design future clinical trials.To update current Diagnosis-Specific Graded Prognostic Assessment (DS-GPA) non-small-cell (NSCLC) The DS-GPA based on data from diagnosed between 1985...
Abstract BACKGROUND: Stereotactic body radiotherapy (SBRT) is a technique used to deliver high, ablative doses of radiation in limited number fractions ≥1 extracranial target(s). To the authors' knowledge, prevalence SBRT use among oncologists United States unknown. METHODS: A random sample 1600 American was surveyed via e‐mail and facsimile (fax) regarding usage, including year adoption, motivations, disease sites treated, common prescriptions used. RESULTS: Of 1373 contactable physicians,...
Online adaptive radiation therapy (ART) promises the ability to deliver an optimal treatment in response daily patient anatomic variation. A major technical barrier for clinical implementation of online ART is requirement rapid image segmentation. Deformable registration (DIR) has been used as automated segmentation method transfer tumor/organ contours from planning images. However, current computational time DIR insufficient ART. In this work, issue addressed by using computer graphics...
OBJECTIVE The objective of this study was to compare fractionation schemes and outcomes patients with renal cell carcinoma (RCC) treated in institutional prospective spinal stereotactic radiosurgery (SSRS) trials who did not previously undergo radiation treatment at the site SSRS. METHODS Patients enrolled 2 separate protocols SSRS between 2002 2011 were included. A secondary analysis performed on nonirradiated RCC metastases either single-fraction (SF) or multifraction (MF) RESULTS 47 sites...
Purpose To compare the toxicities and cost of proton radiation stereotactic body radiotherapy (SBRT) with intensity-modulated (IMRT) for prostate cancer among men younger than 65 years age private insurance. Methods Using MarketScan Commercial Claims Encounters database, we identified who received between 2008 2015. Patients undergoing therapy SBRT were propensity score–matched to IMRT patients on basis clinical sociodemographic factors. Proportional hazards models compared cumulative...
Online adaptive radiation therapy (ART) is an attractive concept that promises the ability to deliver optimal treatment in response inter-fraction variability patient anatomy. However, it has yet be realized due technical limitations. Fast dose deposit coefficient calculation a critical component of online planning process required for plan optimization intensity modulated (IMRT). Computer graphics processing units (GPUs) are well-suited provide requisite fast performance data-parallel...
Frameless stereotactic radiosurgery is commonly used to treat intracranial metastases, but mask-based immobilization can be uncomfortable for patients.To describe the clinical outcomes using a novel real-time, frameless, surface imaging--guided (SIG-RS) technique brain metastases.Data were prospectively gathered 44 consecutive patients totaling 115 metastases treated with SIG-RS in median of 1 fraction (range, 1-5) dose 20 Gy 15-30 Gy). Local control, regional and overall survival estimated...
Abstract Background: Cancer-specific mortality (CSM) is known to be higher among blacks and lower Hispanics compared with whites. Private insurance confers CSM benefit, but few studies have examined the relationship between status racial disparities. We sought determine differences in races within subgroups. Methods: A population-based cohort of 577,716 patients age 18 64 years diagnosed one 10 solid malignancies causing greatest over 2007 2012 were obtained from Surveillance, Epidemiology,...
Background: Metastatic deposits to the spine in thyroid cancer patients represent most common site of bone involvement and can contribute pain, neurologic deficits, death. This study sought determine efficacy safety stereotactic radiosurgery (SSRS) for patients. Methods: Thyroid with metastases were selected analyzed from a cohort who prospectively enrolled two single-institution Phase I/II studies. SSRS was delivered single or multi-fraction schedules. Dose regimens ranged 16–18 Gy one...
Stereotactic body radiation therapy (SBRT) is a technique used to deliver high, ablative doses of in limited number fractions ≥1 extracranial target(s). Although recent studies have shown that SBRT provides effective local tumor control medically inoperable early-stage lung cancer patients, its implementation clinical practice unknown.A random sample 1600 American oncologists was surveyed regarding usage, including year adopted, most common prescription, respiratory motion management, and...
Background Esthesioneuroblastoma (ENB) is a rare cancer of the nasal cavity in children. Radical surgery followed by postoperative radiation considered standard care adults. A similar approach children can lead to significant long-term morbidity. Procedure retrospective multi-institutional review patients less than 21 years age diagnosed with ENB between 1990 and 2014 was performed. Clinical features, treatment, outcome were obtained from medical records. Results Twenty-four identified...
To describe the feasibility and benefits of implementing a custom radiation oncology electronic data capture (EDC) system in large academic practice.A Web-based point-and-click EDC known as Brocade was internally developed implemented systemwide 2016. captures key elements, such stage, histology, patient treatment characteristics; links this information to dose extracted from record verify system; creates clinical notes that are automatically exported hospital health record. We report number...