A5037929406- Cervical Cancer and HPV Research
- Retinoids in leukemia and cellular processes
- Cancer-related molecular mechanisms research
- SARS-CoV-2 and COVID-19 Research
- Animal Virus Infections Studies
- Lung Cancer Treatments and Mutations
- Gene expression and cancer classification
- Genital Health and Disease
- COVID-19 epidemiological studies
- Cancer Genomics and Diagnostics
- Bacteriophages and microbial interactions
- Genetic factors in colorectal cancer
- Immunotherapy and Immune Responses
- Molecular Biology Techniques and Applications
- Cancer-related Molecular Pathways
- Neurofibromatosis and Schwannoma Cases
- Cancer, Stress, Anesthesia, and Immune Response
- Genomics and Phylogenetic Studies
- Gene Regulatory Network Analysis
- Milk Quality and Mastitis in Dairy Cows
- Down syndrome and intellectual disability research
- Respiratory viral infections research
- Thyroid Cancer Diagnosis and Treatment
- Mathematical and Theoretical Epidemiology and Ecology Models
- Lattice Boltzmann Simulation Studies
Universidad Autónoma del Estado de Morelos
2015-2021
Laboratorios Ruiz
2018
Universidad Nacional Autónoma de México
2014-2018
Universidad Autónoma Monterrey
2018
Mexican Social Security Institute
2003-2012
Universidad de Guanajuato
2012
Centro Medico Nacional Siglo XXI
2011
Bank of Mexico
1995
Centre d'Analyse et de Mathématique Sociales
1994
Université Paris Cité
1994
Human Papillomavirus (HPV) in cervical epithelium has been identified as the main etiological factor developing of Cervical Cancer (CC), which recently become a public health problem Mexico. This finding allowed for development vaccines that help prevent this infection. In present study, we aimed to determine prevalence and HPV type-distribution Mexican women with CC, high-grade squamous intraepithelial lesion (HSIL), low-grade (LSIL), Normal cytology (N) estimate impact vaccines.The PubMed...
The aetiological relationship between human papillomavirus (HPV) infection and cervical cancer (CC) is widely accepted. Our goal was to determine the prevalence of HPV types in Mexican women attending at Institute for Social Security from different areas Mexico.DNAs 2,956 samples were subjected genotyping: 1,020 with normal cytology, 931 low-grade squamous intraepithelial lesions (LGSIL), 481 high grade HGSIL 524 CC.Overall 67.1%. A total 40 found; HPV16 detected 39.4% HPV-positive followed...
Ten publicly available metagenomic data sets from hydrothermal vents were analyzed to determine the taxonomic structure of viral communities present, as well their potential metabolic functions. The type natural selection on two auxiliary genes was also analyzed. virome in quite different comparison with viruses present sediments, specific populations being greater abundance plume samples when compared sediment samples. ssDNA genomes such Circoviridae and Microviridae predominantly samples,...
Abstract We develop a model for simulating the growth of biofilm in tortuous tube. The solutions to Navier‐Stokes equations and advection‐diffusion equation are calculated numerically using finite differences. These then coupled with model. © 1994 John Wiley & Sons, Inc.
We formulate a susceptible-vaccinated-infected-recovered (SVIR) model by incorporating the vaccination of newborns, vaccine-age, and mortality induced disease into SIR epidemic model. It is assumed that period immunity vaccines varies depending on vaccine-age. Using direct Lyapunov method with Volterra-type function, we show global asymptotic stability infection-free endemic steady states.
The purpose of this work was to identify and measure catecholamines, their metabolites, the gene expression catecholamine receptors in osteosarcoma tissue.The levels 3,4-dihydroxyphenylacetic acid, norepinephrine, serotonin, 5-hydroxyindoleacetic acid cancer tissue adjacent non-oncological bone were analysed by high-performance liquid chromatography, dopamine β-hydroxylase, monoaminoxidase, ki67, Runx2 tissue, tumour, bone, human brain RT-PCR.We found significantly higher norepinephrine...
Aims The authors have previously reported that cellular retinol-binding protein 1 ( CRBP1 ) gene gain and its expression correlated significantly with survival in laryngeal carcinoma patients. hypothesised inactivation of the through CpG methylation is associated patient status expression. In this work, determine correlation clinical variables Methods promoter was assessed by specific PCR analysis tissue samples from larynx cancer specimens immunohistochemistry on paraffin embedded using...
The relationship between Human Papillomavirus (HPV) infection and conjunctiva cancer is controversial. HPV detection will provide more information about the role of this infectious agent in biology cancer. In present study, DNA extracted purified from 36 Conjunctival Squamous Cell Carcinomas (CSCC) was evaluated by PCR for sequences. results were correlated with clinical histopathological variables.The showed that 8 CSCC samples (22%); HPV16 sole type detected. Significant association found...
Human papillomavirus (HPV) has been identified as the main etiological factor in developing of cervical cancer (CC). This finding propitiated development vaccines that help to prevent HPVs 16 and 18 infection. Both genotypes are associated with 70% CC worldwide. In present study, we aimed determine emergence high-risk nonvaccine HPV after actual vaccination scheme estimate impact current vaccines. A SIR-type model was used study dynamics vaccination. According results, our indicates...
BACKGROUND: Clinically non-functioning Pituitary Adenomas (NFPA) are among the most common neoplasms of sellar region. They usually present with compressive symptoms such as headache and visual field defects not infrequently, found incidentally. NFPA classified gonadotropinomas, null cell adenomas, according to their immunohistochemical phenotype. The molecular alterations responsible for development these lesions incompletely understood, there is scarce information regarding markers....
Introduction: In Head and Neck (HN) cancer, the High-Risk Human Papillomavirus (hr HPV) infection has been associated in about 40% of these tumors. The hr HPV is one etiological factors several epithelial tumors; however, its association with prognosis not yet established for patients Laryngeal Squamous Cell Carcinoma (LSCC). On other hand, Epidermal Growth Factor Receptor (EGFR) a molecular marker widely studied cancer overexpression poor some types including HN cancer. present study, we...
Similarities between the pathologic progression of cancer and physiologic process placentation have been recognized for many years proposing that both present similar mechanisms processes. Cervical (CC) is one most frequent neoplasia among Mexican women turning it into an important health problem.The aim this study was to determine degree involvement pregnancy related genes in by in-silico analysis validated CC samples.The data mining resulted identification expressed term placenta, first...
Aims Neurofibromin 1 (NF1) as a tumour suppressor gene can give rise to several transcripts by an alternative splicing event, generated at least for CELF cofactors. At present, the NF1 isoforms and in sporadic breast cancer are unknown. The aim of authors was detect expression, isoform ratio present cancer. Methods RAS expression were analysed on tissue microarrays containing (n=22), benign lesions (n=18, including six fibroadenomas, fibrocystic changes ductal hyperplasias) normal (n=6)...
Background: The purpose of this study was to determine the prevalence refractive errors in Mexican patients with keratoconus (KCN) and describe their clinical characteristics. Methods: In retrospective study, we reviewed records KCN for year 2012. Criteria classifying included following: emmetropia -0.25 +0.25 sphere, myopia >-0.25 hyperopia >+0.25 astigmatism >-1.00 cylinder. Patient information collected on refraction results, diagnosis, slit-lamp examination, keratometry values, contact...
Abstract Background Association between DNA alterations and clinical parameters as recurrence, survival or prognosis has been found in a variety of tumors. A clear association Medullary Thyroid Carcinoma (MTC) RET oncogene mutation accepted. Specifically M918T represents the main genetic event most cases sporadic MTC (SMTC) limited chromosomal analyses have performed. Methods In present work, comparative genomic hybridization (CGH) study was performed using from primary tumor...
Computational modeling has been applied to simulate the heterogeneity of cancer behavior. The development Cervical Cancer (CC) is a process in which cell acquires dynamic behavior from non-deleterious and deleterious mutations, exhibiting chromosomal alterations as manifestation this dynamic. To further determine progression precursor lesions CC, we introduce computational model study dynamics mutations an outcome tumor progression. analysis mediated by our reveals that multiple are more...
<p class="p1"><span class="s1"><strong>Resumen </strong></span>| Los datos de mortalidad en la población humana por cáncer son contundentes. Pese a los enormes esfuerzos e inversión investigación acerca sus causas, actualidad es tercera causa muerte nivel mundial. El estudio del se ha centrado visión genético-molecular; desde este enfoque disciplinar, han dilucidado ciertas características genéticas célula transformada y factores ambientales que tienen capacidad...
Abstract Human Papillomavirus (HPV) infection is the most common sexually transmitted disease in humans. About 200 HPV types have been described and classified into high low oncogenic risk for its ability to transform cell. Some main factors are multiple sexual partners, multiparity immunosuppression. However, these can not completely explain prevalence different world regions. Mexico has a global burden, being important determine other external biological implicated. The mediated by surface...