A5061553965- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Cervical Cancer and HPV Research
- Uterine Myomas and Treatments
- Breast Lesions and Carcinomas
- Endometriosis Research and Treatment
- Renal cell carcinoma treatment
- Sarcoma Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Cancer Genomics and Diagnostics
- Cancer Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Neuroblastoma Research and Treatments
- Bladder and Urothelial Cancer Treatments
- Neuroendocrine Tumor Research Advances
- Urinary and Genital Oncology Studies
- Renal and related cancers
- Genital Health and Disease
- Cancer and Skin Lesions
- Lung Cancer Research Studies
- Gynecological conditions and treatments
- Global Cancer Incidence and Screening
- Urologic and reproductive health conditions
- Intraperitoneal and Appendiceal Malignancies
- Gastric Cancer Management and Outcomes
Centro Medico Nacional Siglo XXI
2012-2024
Universidad Mexicana
2012-2023
Hospital Médica Sur
2013-2023
Mexican Social Security Institute
2012-2022
Centro Médico ABC
2007-2022
Memorial Sloan Kettering Cancer Center
2017-2022
Sheba Medical Center
2020-2022
Hospital General de México
2009-2022
Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș
2017-2022
Belfast Health and Social Care Trust
2017-2022
We conducted a large international study to estimate fractions of head and neck cancers (HNCs) attributable human papillomavirus (HPV-AFs) using six HPV-related biomarkers viral detection, transcription, cellular transformation. Formalin-fixed, paraffin-embedded cancer tissues the oral cavity (OC), pharynx, larynx were collected from pathology archives in 29 countries. All samples subject histopathological evaluation, DNA quality control, HPV-DNA detection. Samples containing further HPV...
Knowledge about human papillomaviruses (HPV) types involved in anal cancers some world regions is scanty. Here, we describe the HPV DNA prevalence and type distribution a series of invasive intraepithelial neoplasias (AIN) grades 2/3 from 24 countries. We analyzed 43 AIN cases 496 diagnosed 1986 to 2011. After histopathological evaluation formalin-fixed paraffin-embedded samples, detection genotyping was performed using SPF-10/DEIA/LiPA25 system (version 1). A subset 116 further tested for...
We sought to classify endocervical adenocarcinomas (ECAs) based on morphologic features linked etiology (ie, human papillomavirus [HPV] infection), unlike the World Health Organization 2014 classification. The International Endocervical Adenocarcinoma Criteria and Classification (IECC criteria), described herein, distinguishes between papillomavirus-associated adenocarcinoma (HPVA), recognized by presence of luminal mitoses apoptosis seen at scanning magnification, no or limited HPVA...
The aggregate literature suggests that chromophobe renal cell carcinoma (RCC) is biologically a tumor of low malignant potential with reported 5-year and 10-year survival rates 78% to 100% 80% 90%, respectively. conventional prognostic parameters determine the outcome tumors progress remain be fully characterized. Clinicopathologic features 145 cases were correlated outcome. mean age patients was 59 years (range, 27 82) male female ratio 1.1:1. Most well circumscribed averaged 8.0 cm 1.0...
Although endometrial carcinoma (EC) is generally considered to have a good prognosis, over 20% of women with EC die their disease, projected increase in both incidence and mortality the next few decades. The aim accurate prognostication ensure that patients receive optimal treatment are neither overtreated nor undertreated, thereby improving patient outcomes overall. Patients can be categorized into prognostic risk groups based on clinicopathologic findings. Other than tumor type grade,...
Chromophobe renal cell carcinoma (RCC) is a histologic subtype of RCC that portends favorable prognosis. It controversial whether the Fuhrman nuclear grade chromophobe has prognostic utility. Irregular nuclei, prominent nucleoli, and pleomorphism are inherently present in RCC. Hence, higher even though majority these tumors have outcome. In this study, utility novel 3-tiered tumor grading system which innate atypia was discounted, herein referred to as from series 124 RCC, compared with...
The management of endocervical adenocarcinoma is largely based on tumor size and depth invasion (DOI); however, DOI difficult to measure accurately. surgical treatment includes resection regional lymph nodes, even though most nodes are negative lymphadenectomies can cause significant morbidity. We have investigated alternative parameters better identify patients at risk node metastases. Cases invasive from 12 institutions were reviewed, clinical/pathologic features assessed: patients' age,...
The International Endocervical Adenocarcinoma Criteria and Classification (IECC) categorizes endocervical adenocarcinomas (ECAs) on the basis of morphologic features linked to etiology (ie, human papilloma virus [HPV] infection), resulting in separation ECAs into HPV-associated (HPVA) unassociated or non-HPVA (NHPVA) types. NHPVAs are reported be large present at high stage older individuals. Our aim was examine clinical outcomes these tumor Full slide sets 205 were collected from 7...
A new 3-tier pattern-based system to classify endocervical adenocarcinoma was recently presented. In short, pattern tumors were characterized by well-demarcated glands frequently forming clusters or groups with relative lobular architecture. Pattern B demonstrated localized destructive invasion defined as desmoplastic stroma surrounding irregular and/or ill-defined borders incomplete and associated tumor cells (individual small clusters) within the stroma. Tumors C showed diffusely...
The International Endocervical Adenocarcinoma Criteria and Classification was developed to separate endocervical adenocarcinomas (ECAs) into 2 main categories on the basis of morphology such as human papilloma virus-associated (HPVA) non-human adenocarcinomas. We aimed improve diagnostic accuracy by performing a comprehensive immunohistochemical evaluation constructing objective immunohistochemical-based algorithms for classification these tumors. Tissue microarrays were constructed from 297...
The recent finding that lobular, and not ductal intraepithelial neoplasia (DIN) displays loss of E-cadherin expression has greatly facilitated the categorization a large proportion morphologically ambiguous neoplasias into or lobular types. One reason for such morphologic ambiguity is presence comedo-type necrosis within an lesion otherwise shows archetypal cytologic architectural features (LIN). clinicopathologic 18 cases are described in this report. These classic LIN were accumulated from...
Although well recognized in the literature, contemporary clinicopathologic data regarding choriocarcinoma (CC) as a pure or predominant component of testicular germ cell tumor (GCT) are limited. Herein, we present series CC and mixed GCT testis obtained from single oncology institution. A comprehensive histologic review 1010 orchiectomies 1999 to 2011 yielded 6 (0.6%) 9 (0.9%) cases with component. Patients' ages ranged 20 39 years (median 29 y). All patients had markedly elevated serum...
Endometrial cancer is the most common gynecologic neoplasm in developed countries; however, updated universal guidelines are currently not available to handle specimens obtained during surgical treatment of patients affected by this disease. This article presents recommendations on how gross and submit sections for microscopic examination hysterectomy other tissues removed management endometrial such as salpingo-oophorectomy, omentectomy, lymph node dissection—including sentinel nodes. In...