Fan Wang

ORCID: 0000-0002-7048-8166
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About
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Research Areas
  • Traditional Chinese Medicine Studies
  • Healthcare and Venom Research
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Acupuncture Treatment Research Studies
  • Obstructive Sleep Apnea Research
  • Neurological Disease Mechanisms and Treatments
  • Medical Research and Treatments
  • Suicide and Self-Harm Studies
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Neurosurgical Procedures and Complications
  • Head and Neck Surgical Oncology
  • Diet and metabolism studies
  • Folate and B Vitamins Research
  • Neuroscience of respiration and sleep
  • Tracheal and airway disorders
  • Maternal Mental Health During Pregnancy and Postpartum
  • Treatment of Major Depression
  • Neuroendocrine Tumor Research Advances
  • Medicinal Plant Pharmacodynamics Research
  • Plant-based Medicinal Research
  • Gastrointestinal motility and disorders
  • Hernia repair and management
  • Bone Metabolism and Diseases
  • Lipid metabolism and disorders
  • Lung Cancer Treatments and Mutations

Second Affiliated Hospital of Xinjiang Medical University
2021-2025

Xinjiang Medical University
2021-2025

Peking University
2010-2025

Beijing HuiLongGuan Hospital
2021-2025

Soochow University
2021-2024

Anhui Medical University
2013-2024

Baoding People's Hospital
2023

Shanghai Jiao Tong University
2014-2022

Shanghai Sixth People's Hospital
2019-2022

First Affiliated Hospital of Anhui Medical University
2013-2021

The aim of this study was to determine the clinical features, treatment factors, and prognosis patients with multiple primary malignant tumors (MPMTs). In total, 161 MPMTs at our hospital (The First Affiliated Hospital Xi'an Jiaotong University, Xi'an, Shaanxi, China) were analyzed in study. We found that among MPMTs, 78 (48.4%) had synchronous 83 (51.6%) metachronous tumors. Most pathological features similar both groups. men older (>50 years old), adenocarcinoma most frequent pathology...

10.1097/md.0000000000006799 article EN cc-by-nc Medicine 2017-04-01

Psychological status is a decisive factor for regulating the lung cancer chemotherapy patients' levels of fatigue and hope. Using PERMA (Positive Emotion, Engagement, Relationships, Meaning, Accomplishment) framework. We aimed to explore influences psychological intervention on negative emotion, cancer-related fatigue, level hope.A total 100 patients admitted in Wuhan No.4 Hospital, China, from Jan 2018 Aug 2019 were enrolled as research objects divided into control group observation group....

10.18502/ijph.v50i4.5997 article EN cc-by-nc Iranian Journal of Public Health 2021-04-14

This study aims to review and analyze factors associated with suicidal ideation provide a rationale for subsequent effective interventions. Data from this were obtained the Assessing Nocturnal Sleep/Wake Effects on Risk of Suicide (ANSWERS). The University Arizona evaluated 404 young adults aged 18–25 years using different scales. Then, general demographic data was recorded. An elastic network (EN) used optimize feature selection, combined logistic regression, determine influencing SI in...

10.1186/s12888-024-06415-6 article EN cc-by-nc-nd BMC Psychiatry 2025-01-06

Cigarette smoking has been linked to severe and persistent sleep disturbances alongside notable fluctuations in neuropeptide levels. Substance P (SubP), influenced by smoking, also impacts sleep-wake cycles. However, its specific role smoking-induced disorders remains unclear. This study aimed explore the connection between cigarette quality examining SubP levels cerebrospinal fluid (CSF) identifying potential treatment avenues for disorders. A total of 146 Chinese men (93 nonsmokers, 53...

10.1002/brb3.70296 article EN cc-by Brain and Behavior 2025-02-01

Cigarette smoking increases both the risk for insulin resistance and amyloid-β (Aβ) aggregation, impaired brain insulin/insulin-like growth factor 1 (IGF1) signaling might increase factors Alzheimer's disease (AD). We aimed to investigate association among cerebrospinal fluid (CSF) sensitivity/IGF1, glucose/lactate, Aβ42 further explore whether sensitivity contributed AD in active smokers. In this cross-sectional study, levels of insulin, IGF1, lactate/glucose 75 smokers 78 nonsmokers CSF...

10.1002/brb3.3432 article EN cc-by Brain and Behavior 2024-02-01

Abstract Panitumumab (ABX-EGF or Vectibix), the first fully human monoclonal antibody targeting epidermal growth factor receptor (EGFR), was approved by Food and Drug Administration for treatment of patients with metastatic colorectal cancer. Here, we report time radioimmunotherapy (RIT) EGFR-positive head neck cancer in a nude mouse model using pure β− emitter 90Y-labeled panitumumab. Biodistribution planar γ-imaging studies were carried out 111In-DOTA-panitumumab. The RIT efficacy...

10.1158/1535-7163.mct-10-0444 article EN Molecular Cancer Therapeutics 2010-08-01

The objective of this study was to investigate the effects Rosiglitazone (RSG) infusion therapy following minimally invasive surgery (MIS) for intracerebral hemorrhage(ICH) evacuation on perihematomal secondary brain damage as assessed by MMP-9 levels, blood-brain barrier (BBB) permeability and neurological function.A total 40 male rabbits (2.8-3.4 kg) randomly assigned a normal control group (NC group; 10 rabbits), model (MC treatment (MIS rabbits) or combined MIS RSG + rabbits). ICH...

10.1186/s12883-015-0287-3 article EN cc-by BMC Neurology 2015-03-16

Almost half of patients with major depressive disorder (MDD) also have clinically meaningful levels anxiety. Anxious depression is a distinct clinical subtype MDD, which has poor response to pharmacotherapy; however, the neural mechanisms behind are largely unknown. In present study, we explored white matter (WM) integrity traits anxious in first-episode and medication-free (medication-naïve medication washout) Chinese young adult by detecting differences diffusion tensor imaging (DTI)...

10.2147/ndt.s169583 article EN cc-by-nc Neuropsychiatric Disease and Treatment 2018-08-01

To study the association between IL-6 level and seizure recurrence in patients with first post-ischemic stroke assess its predictive value for recurrence.A total of 2976 consecutive ischemic were retrospectively enrolled. Among them, 209 (7.02%) included this analysis. The mRNA expression was evaluated through quantitative real-time PCR (qRT-PCR) 2-ΔΔCt method. Demographic data clinical characteristics collected. Univariate analysis performed independent-samples t-test, Mann-Whitney U-test,...

10.2147/ndt.s257870 article EN cc-by-nc Neuropsychiatric Disease and Treatment 2020-08-01

Several clinical trials have proven that icotinib hydrochloride, a novel epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor, exhibits encouraging efficacy and tolerability in patients with advanced non-small-cell lung cancer (NSCLC) who failed previous chemotherapy. This study was performed to assess the toxicity of as first-line therapy for pulmonary adenocarcinoma EGFR-sensitive mutation.Thirty-five NSCLC mutation were sequentially admitted First Affiliated Hospital Xi'an...

10.2147/ott.s98363 article EN OncoTargets and Therapy 2016-02-01

Abstract A higher dietary intake or serum concentration of betaine has been associated with greater lean body mass in middle-aged and older adults. However, it remains unknown whether is age-related loss skeletal muscle (SMM). We assessed the association between relative changes SMM after 3 years total 1242 participants aged 41–60 from Guangzhou Nutrition Health Study 2011–2013 2014–2017 composition measurements by dual-energy X-ray absorptiometry were included. face-to-face questionnaire...

10.1017/s0007114520002433 article EN British Journal Of Nutrition 2020-07-03

The objective of our study was to evaluate the effects upper-airway surgery on improvement endothelial function-related markers in patients with obstructive sleep apnea (OSA). Subjects moderate severe OSA who underwent surgery, a follow-up duration at least 6 months, were included. Pre- and postoperative polysomnographic variables compared. Subgroup correlation analyses conducted find possible indicators for better after surgery. In total, 44 mean 1.72 ± 0.92 years. Serum VEGFA [-20.29 (CI:...

10.1038/s41598-019-56601-w article EN cc-by Scientific Reports 2019-12-27
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