A5091710067- RNA Research and Splicing
- RNA modifications and cancer
- RNA and protein synthesis mechanisms
- Plant Disease Resistance and Genetics
- Soybean genetics and cultivation
- Traffic control and management
- Plant Molecular Biology Research
- Cancer-related molecular mechanisms research
- Aviation Industry Analysis and Trends
- Air Traffic Management and Optimization
- CRISPR and Genetic Engineering
- Vehicle Routing Optimization Methods
- Plant Pathogens and Fungal Diseases
- Genetics, Aging, and Longevity in Model Organisms
- MicroRNA in disease regulation
- Plant Genetic and Mutation Studies
- Evacuation and Crowd Dynamics
- Robotic Path Planning Algorithms
- Electric Motor Design and Analysis
- Context-Aware Activity Recognition Systems
- Dendrimers and Hyperbranched Polymers
- Heat shock proteins research
- Metaheuristic Optimization Algorithms Research
- Multiple Myeloma Research and Treatments
- Advanced Data Processing Techniques
Center for Life Sciences
2022-2024
Tsinghua University
2022-2024
Meizhou City People's Hospital
2024
Inner Mongolia University
2024
Beihang University
2024
Nanjing Tech University
2024
Nanjing University of Aeronautics and Astronautics
2021-2023
Nanjing Agricultural University
2017-2021
Boston VA Research Institute
2019-2021
Harvard University
2019-2021
ObjectivesThe objectives of this study were to determine species distribution and in vitro antifungal susceptibility Candida isolates identified the multicentre China-SCAN invasive infection (ICI) intensive care units (ICUs) across China.
The nodal-line semimetals have attracted immense interest due to the unique electronic structures such as linear dispersion and vanishing density of states Fermi energy approaching nodes. Here, we report temperature-dependent transport scanning tunneling microscopy (spectroscopy) [STM(S)] measurements on semimetal ZrSiSe. Our experimental results theoretical analyses consistently demonstrate that temperature induces Lifshitz transitions at 80 106 K in ZrSiSe, which anomalies same...
Aiming at enhancing the electrochemical performance of cathode material NaNi0.5Mn0.5O2 (NM) for sodium ion battery, a novel Indium-intercalated NaNi0.5-xMn0.5InxO2 enriched with oxygen vacancies was first synthesized via high-shear...
MicroRNAs (miRNAs) play essential roles in plant growth, development and stress responses through post-transcriptionally regulating the expression levels of their target mRNAs. Although some tools databases were developed for predicting relationships between miRNAs targets (miR-Tar), most them dependent on computational methods without experimental validations. With degradome sequencing techniques, researchers can identify potential interactions based data. The validations with specific data...
Usually the microRNA (miRNA)-mediated gene regulatory network (GRN) is constructed from investigation of miRNA expression profiling and target predictions. However, higher/lower level miRNAs does not always indicate cleavages such analysis, thus, sometimes ignores crucial cleavage events. In present work, degradome sequencing data were employed to construct complete miRNA-mediated in soybean, unlike traditional approach starting with small RNA data.We root-, cotyledon-, leaf- seed-specific...
Small regulatory RNAs, such as small interfering RNAs (siRNAs) and PIWI-interacting regulate splicing, transcription, genome integrity in many eukaryotes. In
Abstract Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) positively affect the initial control of non-small cell lung cancer (NSCLC). Rapidly acquired resistance to EGFR-TKIs is a major hurdle in successful treatment. However, mechanisms that remain largely unknown. RNA structures have widespread and crucial functions many biological regulations; however, regulating drug unclear. Here, psoralen analysis interactions (PARIS) method used establish higher-order structure...
Abstract Summary A critical aspect for exploring the biological function of a microRNA (miRNA) lies on exact detection and validation its target mRNAs. However, no convenient efficient web-based server is available plant biologists to identify experimentally verified mRNAs miRNAs. In this work, we built comprehensive platform miRNA–target analysis, named as Whole-degradome-based Plant MiRNA–target Interaction Analysis Server (WPMIAS), predicted interactions miRNAs their (MTIs) by...
Phased siRNAs (phasiRNAs) are a class of small interfering RNAs (siRNAs) which play essential roles in plant development and defence. However, only few phasiRNAs have been extensively studied due to the difficulties identifying characterizing by biologists. Herein, we describe comprehensive multi-functional web server termed PhasiRNAnalyzer, is able identify all crucial components phasiRNA's regulatory pathway (phase-initiator→PHAS gene→phasiRNA cluster→target gene). Currently,...
Urban air traffic has gradually attracted attention in recent years, which will bring endless vitality to future urban development. An objective and accurate method of assessing vertiport capacity is the basis for flow management UAVs, plays an important role improving efficiency airspace resources. First all, this paper establishes a theoretical calculation model ground facilities such as takeoff landing platforms, taxiways aprons, respectively. Next, analyzes service characteristics each...
City air traffic as a new transportation mode has gradually attracted attention in recent years which will bring endless vitality to future urban development. An objective and accurate assessment of the vertiport capacity for UAVs (Unmanned Aerial Vehicles) is basis implementing flow management UAVs, also prerequisite improving efficiency airspace resources used. Firstly, topology designs are proposed named connected compact based on existing central airport design. Subsequently, three modes...
In recent years, phased small interfering RNA has been found to play crucial roles in many biological processes plants. However, efficiently predicting phasiRNA regulatory cascades with computational methods is still challenging. Here, we introduce PhasiHunter, a network prediction tool that several distinctive features compared existing tools: (i) PhasiHunter employs two major algorithms, namely phase score and hypergeometric distribution-based methods, ensure the integrity accuracy of...
Abstract Mobile genetic elements threaten genome integrity in all organisms. MUT-2/RDE-3 is a ribonucleotidyltransferase required for transposon silencing and RNA interference (RNAi) C. elegans . When tethered to RNAs heterologous expression systems, RDE-3 can add long stretches of alternating non-templated uridine (U) guanosine (G) ribonucleotides the 3’ termini these (polyUG or pUG tails). Here, we show that, its natural context , adds tails RNAs, as well targets RNAi. with more than 16...
Abstract Non-coding RNAs (ncRNAs) play important roles in regulating expression of protein-coding genes. Although gene databases have emerged a timely manner, comprehensive database for ncRNAs is still lacking. Herein, we constructed rice ncRNA co-expression atlas (RiceNCexp), based on 491 RNA-seq and 274 small RNA (sRNA)-seq datasets. RiceNCexp hosts four types ncRNAs, namely lncRNAs, PHAS genes, miRNAs, phasiRNAs. provides information 22 tissues/organs, an efficient tau-based mining tool...
Aiming at the problem of path planning and evaluation logistics UAV (Unmanned Aerial Vehicle) in urban area, paper plans flight by using improved A-star algorithm. The algorithm considers airspace restrictions performance constraints from perspectives delivery efficiency cost. At same time, deeply analyzes influencing factors four aspects. These aspects are external environment, route conditions, distribution, influence. Then, constructs index system according to characteristics airspace....
RNA molecules function in numerous biological processes by folding into intricate structures. Here we present RASP v2.0, an updated database for structure probing data featuring a substantially expanded collection of datasets along with enhanced online structural analysis functionalities. Compared to the previous version, v2.0 includes following improvements: (i) number has increased from 156 438, comprising 216 transcriptome-wide datasets, 141 target-specific and 81 RNA-RNA interaction...