A5001283434- Immune Cell Function and Interaction
- COVID-19 Clinical Research Studies
- Chronic Myeloid Leukemia Treatments
- CAR-T cell therapy research
- Acute Myeloid Leukemia Research
- Social Work Education and Practice
- Interprofessional Education and Collaboration
- Chronic Lymphocytic Leukemia Research
- COVID-19 and Mental Health
- T-cell and B-cell Immunology
- Antibiotic Resistance in Bacteria
- Immune cells in cancer
- Extracellular vesicles in disease
- Digital Mental Health Interventions
- Social Media in Health Education
- Long-Term Effects of COVID-19
- Adolescent Sexual and Reproductive Health
- Inflammatory Biomarkers in Disease Prognosis
- Calcium signaling and nucleotide metabolism
- Personality Disorders and Psychopathology
- Nanowire Synthesis and Applications
- Infections and bacterial resistance
- Medical Research and Treatments
- China's Ethnic Minorities and Relations
- SARS-CoV-2 detection and testing
Guangdong Ocean University
2025
Guilin University of Technology
2025
Nanjing Medical University
2024
First Affiliated Hospital of Wannan Medical College
2024
Huazhong University of Science and Technology
2017-2022
Zhongnan Hospital of Wuhan University
2022
Wuhan University
2022
University of Houston
2016-2021
Hubei Normal University
2020
Union Hospital
2017-2020
Without an urban hukou, or registered residency status, migrant workers in China have experienced urban–rural cultural divide. Rural who migrate to areas are socially excluded from the mainstream because of hukou national policy and region-specific regulations. In 2014, was revised gradually allow children receive public education cities; however, migrants still challenged by social exclusion discrimination. This study discusses that integrates into educational system analyzes welfare...
ObjectivesThe objectives of this study were to determine species distribution and in vitro antifungal susceptibility Candida isolates identified the multicentre China-SCAN invasive infection (ICI) intensive care units (ICUs) across China.
Mangrove ecosystems are valuable coastal ecosystems; however, studies on the diversity and functional features of their soil fungal communities during restoration limited. In this study, we examined trophic modes across mudflat, young mangrove, mature mangrove stages. We found that Ascomycota Basidiomycota were dominant phyla, with saprotrophs as most abundant mode. The abundance major phyla significantly varied Although alpha (α)-diversity remained stable among stages, beta (β)-diversity...
Soil fungi in mangroves are diverse and crucial for organic matter decomposition element cycling. However, the drivers influencing network complexity stability of fungal communities across different mangrove soil habitats remain unclear. This study investigated main factors driving composition, diversity, complexity, clay loam sandy soils ecosystems. Results showed that Dothideomycetes Sordariomycetes dominated soils, respectively. Sandy exhibited higher alpha diversity than loam. Beta...
Technology-based simulations provide vehicles for social work students to practice clinical skills in online environments. This teaching note reviews 2 simulation tools educators may consider implementing their training programs: virtual patients and Second Life. The current literature is presented discussing the use of these learning programs. Suggestions incorporating into distance education programs are provided along with suggestions future directions research this area. Educators...
T cell function in cancer patients is usually impaired due to the constitutive activation of immune checkpoint inhibitors. This state known as 'exhaustion' and often associated with inefficient control tumors or persistent infections. In this work, we investigated role leukemia cell-derived microvesicles (MVs) exhaustion. Following incubation MVs from various sources, all subtypes exhibited exhaustion phonotype cytokine secretion vitro. Mice models also showed connection between inhibitors...
Objectives: To analyze follow-up CTs of patients recovering from COVID-19 in Wuhan, focusing on fibrotic change and its relevant risk factors. Methods: From January 13 to February 27, 2020, 166 hospitalized meeting our criteria were included. The scores patterns CT evaluated. Patients designated as group 1 (with evidence pattern) 2 (without pattern). Multivariate logistic regression was performed explore factors for with COVID-19. Results: obtained 56 days (median, IQR 51–63 days) after...
Background: Immunotherapy utilizing T cells genetically modified to express chimeric antigen receptors (CARs) is rapidly emerging as a promising novel treatment for hematological and nonhematological malignancies. In order target the TKI-insensitive leukemia stem (LSCs) in chronic myeloid (CML) by CAR cells, we chose CD26 cell surface tumor-associated due preferentially expression on LSCs. Additionally, has also been suggested be multipurpose therapeutic other cancer. Therefore, developing...
The goal of China’s new guidelines for physical education within universities is to promote greater levels active engagement and an emphasis on the development cultivation students’ individual abilities. This study follows perspective examine responses stakeholders incorporation essential elements Sport Education elective basketball sports club. Participants were 152 students who after five weeks term could elect participate in a season or continue practice individually. Dependent measures...
Myeloid-derived suppressor cells (MDSCs) are considered to be a strong contributor the immunosuppressive tumor microenvironment. In our study, counts of MDSCs were correlated with remission status CML patients, especially M-MDSCs. M-MDSCs promoted proliferation K562 or CD34+ from newly diagnosed no matter in mice experiments. We also established TKI discontinuation model using cell line for examining effect microvesicles (MVs) derived before and after on MDSCs. found mutual promotion...
BACKGROUNDGraft-vs-host disease (GVHD) is a major cause of mortality after allogeneic hematopoietic stem cell transplantation.Some patients have steroid-refractory (SR) GVHD. AIMTo evaluate the effect and safety ruxolitinib add-on in treatment with SR acute (a) chronic (c)
Purpose: This article provides benchmark data on within-group effect sizes from published randomized clinical trials supporting the efficacy of dialectical behavioral therapy (DBT) for borderline personality disorder (BPD) in adults aged 18–65 years. Method: Within-group were calculated via Glass approach and adjusted sample size using Hedges’s g then aggregated to produce benchmarks symptoms commonly associated with BPD, such as self-harm, depression, anger. Results: Aggregate are presented...
Eleven doctoral interns and 9 faculty mentors participated in a two-year Teaching Mentorship Project (TMP). Qualitative analyses of 20 interviews reflective writing by the resulted six themes: preparation guidance from mentors; teaching innovation; rehearsal with intern peers; mentor-intern reciprocal support; readiness/empowerment; pedagogical reflexivity. Interns valued empowerment, intern-mentor support, innovative styles methods. Mentors envisioned essentiality adding mentorship to...
In late December 2019, COVID-19 was firstly recognized in Wuhan, China and spread rapidly to all of the provinces China. The West Campus Wuhan Union Hospital, designated hospital admit treat severe critically ill cases, has treated a large number such patients with great success obtained lots valuable experiences based on Chinese guideline (V7.0). To standardize share treatment procedures Hospital established working group formulated an operational recommendation, including monitoring, early...
COVID-19 has highlighted the need for evidence-based behavioural health interventions that can be delivered remotely. This article provides within-group effect size benchmarks randomised controlled trials of Internet-based Acceptance and Commitment Therapy treatment adults with anxiety depression. Effect sizes were calculated using Glass approach, adjusted Hedges g, then aggregated to produce separate measures These used by community-based providers evaluate effectiveness their web-based...
BCR-ABL1 tyrosine kinase inhibitors (TKIs) are selective therapies for patients with chronic myeloid leukemia (CML) and induce deep molecular response (DMR). However, ∼60% of relapse after the discontinuation TKIs. Relapse is likely due inability TKIs to eradicate CML stem cells (CML-LSCs). In our previous study, 12 out 22 maintained a stable DMR TKI withdrawal, we found that fewer who were treated second-generation relapsed compared those receiving imatinib. Therefore, hypothesized imatinib...
Stenotrophomonas maltophilia is an opportunistic pathogen associated with various nosocomial infections and known for its intrinsic multidrug resistance. This study aims to provide a comprehensive overview of the epidemiology resistance patterns S. in China from 2014 2021. Data were extracted Antimicrobial Resistance Surveillance System (CARSS) Blood Bacterial Investigation Collaborative (BRICS), encompassing 1412 medical institutions across 31 provinces China. We analyzed prevalence...
This study examines the process of shifting from being a frontline worker to performing supervisory role, focusing on challenges faced by new supervisors during this transition. Semi-structured interviews were conducted with 24 different practice settings in large southern city US. The phenomenological method was employed data analysis. findings indicate that most significant included peer-to-supervisor transition, an overwhelming workload, unclear role expectations, and managing seasoned...
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