A5045233806- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Asphalt Pavement Performance Evaluation
- Natural Language Processing Techniques
- Moyamoya disease diagnosis and treatment
- Cerebrovascular and Carotid Artery Diseases
- Translation Studies and Practices
- Infrastructure Maintenance and Monitoring
- Recycled Aggregate Concrete Performance
- Traumatic Brain Injury and Neurovascular Disturbances
- Text Readability and Simplification
- Spinal Fractures and Fixation Techniques
- Neurosurgical Procedures and Complications
- Acute Ischemic Stroke Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Physics of Superconductivity and Magnetism
- Neurological Complications and Syndromes
- Cerebral Venous Sinus Thrombosis
- Advanced Condensed Matter Physics
- Trigeminal Neuralgia and Treatments
- Crystallization and Solubility Studies
- Grouting, Rheology, and Soil Mechanics
- Innovative concrete reinforcement materials
- X-ray Diffraction in Crystallography
- linguistics and terminology studies
Rikkyo University
2014-2024
Yamato Municipal Hospital
1994-2022
Nagoya University
1988-2022
Kansai University
2016-2021
University of Portsmouth
2020
Chiba University
2020
Kansai Electric Power (Japan)
1991-2019
Kitasato University
2005-2015
Osaka City University
1991-2009
Yokufukai Hospital
2007
Background and Purpose— About one half of those who develop adult-onset moyamoya disease experience intracranial hemorrhage. Despite the extremely high frequency rebleeding attacks poor prognosis, measures to prevent have not been established. The purpose this study is determine whether extracranial–intracranial bypass can reduce incidence improve patient prognosis. Methods— This was a multicentered, prospective, randomized, controlled trial conducted by 22 institutes in Japan. Adult...
Background and Purpose —The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) lower serum cholesterol decrease the incidence of stroke cardiovascular disease. There is growing evidence that statins exert some their beneficial effects independent lowering. Indeed, we have previously demonstrated chronic simvastatin administration upregulates endothelial nitric oxide synthase (eNOS), resulting in more functional protein, augmentation cerebral blood flow,...
Cerebral blood flow is regulated by endothelium-derived nitric oxide (NO), and endothelial NO synthase–deficient (eNOS-deficient; eNOS–/–) mice develop larger cerebral infarctions following middle artery (MCA) occlusion. We report that disruption of Rho-mediated actin cytoskeleton leads to the upregulation eNOS expression reduces severity ischemia MCA Mice treated with Rho inhibitor Clostridium botulinum C3 transferase (10 μg/d) or disrupter cytochalasin D (1 mg/kg) showed a two- fourfold...
Background and Purpose— The primary results of the Japan Adult Moyamoya Trial revealed statistically marginal superiority bypass surgery over medical treatment alone in preventing rebleeding moyamoya disease. purpose this analysis is to test prespecified subgroup hypothesis that natural course surgical effects vary depending on hemorrhagic site at onset. Methods— site, classified as either anterior or posterior, was only stratifying variable for randomization. Statistical analyses were...
Nitric oxide, a product of nitric oxide synthase activity, relaxes vascular smooth muscle and elevates brain blood flow. We evaluated the importance eNOS to cerebral flow augmentation after L-arginine infusion increases in upregulation SV-129 mice. Blood was measured by laser-Doppler flowmetry before (450 mg/kg during 15-minute period) or 14 C-iodoamphetamine indicator fractionation C-iodoantipyrine tissue equilibration techniques. rCBF increased 26% (laser Doppler flowmetry) but did not...
Object. Intracranial vertebral artery (VA) dissection with subarachnoid hemorrhage is notorious for frequent rebleeding and a poor prognosis. Nevertheless, some patients survive good final outcome. The factors associated the prognosis of this disease are not fully understood appropriate treatment strategies continue to be debated. authors retrospectively evaluated clinical features conservatively treated elucidate relationship between angiographic characteristics outcomes. Methods. This...
Application of endovascular surgery for very small aneurysms is controversial because technical difficulties and high complication rates. The aim in the present study was to assess treatment results a series such lesions at one institution. Since 1997, has been advocated ruptured (< 3 mm maximum diameter) that fulfill criterion fundus/neck ratio greater than 1.5. Twenty-one patients were treated, whom World Federation Neurosurgical Societies classification before Grade I 10, II two, III IV...
Pseudomonas 0–3 strain which was isolated from soil can grow on polyvinyl alcohol (PVA) as a sole carbon source. When 0.5 per cent of PVA (500, 1500 or 2000) employed the source in culture medium, almost completely lost fluid after week and concentration total organic measured by TOC analyzer decreased initial value about 2700 ppm to 250~300 7~10 days culture. This bacterium found produce secrete an inducible enzyme degrade PVA. The way this degrades examined results were obtained suggested...
Although endovascular surgery is now widely used to treat intracranial aneurysms, no comparative studies of clipping versus address distal ACA aneurysms at the same institution are available. We compared results these treatment modalities our institution. treated 68 patients with ruptured (endovascular surgery, n=13; n=55). performed a retrospective comparison outcomes. To study efficacy we classified all cases into three types: type A were small-necked B wide-necked on parent artery, and C...
This study examined the impact of platelet transfusion (PLT) on survival intracerebral hemorrhage (ICH) patients who had been administered anti-platelet agents (APA). retrospective cohort analysis investigated 432 (259 men, 60%) were newly diagnosed with ICH between January 2006 and June 2011 at tertiary emergency center Kitasato University Hospital. Median age arrival was 67.0 years (range, 40–95 years). subcortical in 72 (16.7%), supratentorial 233 (53.9%), infratentorial 133 (30.8%). PLT...
This paper explores the influence of integrating purpose translation and target audience into prompts on quality translations produced by ChatGPT. Drawing previous studies, industry practices, ISO standards, research underscores significance pre-production phase in process. The study reveals that inclusion suitable large-scale language models like ChatGPT can yield flexible translations, a feat yet to be realized conventional Machine Translation (MT). scrutinizes changes when are used...
Although perfusion-weighted imaging techniques are increasingly used to study stroke, no particular hemodynamic variable has emerged as a standard marker for accumulated ischemic damage. To better characterize the signature of infarction, authors have assessed severity and temporal evolution hemodynamics in middle cerebral artery occlusion model rat. Cerebral blood flow (CBF) total microvascular volume (CBV) changes were measured with arterial spin labeling steady-state susceptibility...
The transvenous approach via the inferior petrosal sinus (IPS) is commonly used as most appropriate for carotid-cavernous fistula (CCF) or cavernous sampling. However, sometimes IPS not accessible because of anatomical problems and/or complications, therefore an alternative route needed. In this paper, authors present and discuss utility a to petrooccipital vein.Four patients, 3 with dural CCFs other Cushing disease, in whom endovascular surgical attempts failed using conventional venous...
AbstractAbstractChild patients with Moyamoya disease initially present ischemic symptoms. However, the long-term risk of intracranial hemorrhage for childhood is unknown. Hemodynamic overload to fragile collateral vessels has been considered cause hemorrhage. We reviewed angiograms evaluate effect encephalo-myo-synangiosis (EMS) on abnormally dilated in 13 child disease. EMS was performed 24 sides ranging from 5 14 years age. Post-operative angiography (6-88 months after surgery) revealed...
Background and Purpose To verify the hypothesis that impaired autoregulation may contribute to cerebral swelling or hemorrhage after a sudden recovery of perfusion pressure, we studied chronic effects hypoperfusion on autoregulatory responses pial arterioles in situ. Methods Eight 12 weeks carotid-jugular fistula was created rats, experiments were performed under α-chloralose urethane anesthesia. Regional blood flow (rCBF) determined by hydrogen clearance method, carotid pressure measured....