A5027420060- Glioma Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Head and Neck Cancer Studies
- Radiomics and Machine Learning in Medical Imaging
- Colorectal and Anal Carcinomas
- Bladder and Urothelial Cancer Treatments
- Advances in Oncology and Radiotherapy
- Endometrial and Cervical Cancer Treatments
- Brain Metastases and Treatment
- Medical Imaging Techniques and Applications
- Lung Cancer Treatments and Mutations
- Urinary and Genital Oncology Studies
- Cervical Cancer and HPV Research
- Head and Neck Surgical Oncology
- Lung Cancer Diagnosis and Treatment
- Mentoring and Academic Development
- Cancer, Lipids, and Metabolism
- Radiation Dose and Imaging
- COVID-19 and healthcare impacts
- Radiopharmaceutical Chemistry and Applications
- Management of metastatic bone disease
- Urological Disorders and Treatments
- Diversity and Career in Medicine
The University of Texas MD Anderson Cancer Center
2023-2025
Washington University in St. Louis
2017-2022
University of Missouri–Kansas City
2016-2021
Pomona Valley Hospital Medical Center
2021
Brown University
2021
Massachusetts General Hospital
2021
Harvard University
2021
Rhode Island Hospital
2021
Cleveland Clinic
2021
Cornell University
2021
Patients with inoperable pancreatic adenocarcinoma have limited options, traditional chemoradiation providing modest clinical benefit and an otherwise poor prognosis. Stereotactic body radiation therapy for cancer is by proximity to organs-at-risk (OAR). However, stereotactic magnetic resonance-guided adaptive (SMART) has shown promise in delivering ablative doses safely. We sought demonstrate the benefits of SMART using a 5-fraction approach daily on-table adaptation.Patients locally...
799 Background: Metastasis-directed therapy (MDT) for oligometastatic cancer is a concept utilized prostate and kidney cancer. Clinical research in MDT urothelial carcinoma (UC) remains sparse especially the modern era where systemic advancements have substantially improved patient’s outcomes overall. We explored our institutional experience of patients with bladder upper tract undergoing utilizing radiotherapy (RT). Methods: Patients were retrospectively identified or from January 2016 to...
385 Background: Trials comparing moderately hypofractionated radiotherapy (MHFRT) against conventionally-fractionated (CFRT) for prostate cancer have varied considerably in intent (non-inferiority vs. superiority) and MHFRT dose. Herein, we compare the efficacy toxicity profiles of isodose dose-escalated MHFRT. Methods: Individual patient data were obtained from 7 phase III trials CFRT: three (n=3454) with four (n=2426) Meta-analyses designed to progression-free survival (PFS), late grade ≥2...
Background: Retroperitoneal sarcomas (RPS) are rare and primarily managed with surgery, which improves local recurrence-free overall survival. Radiation can improve control or provide palliation for inoperable metastatic RPS by eliciting tumor cell death via irreparable DNA damage. In extraordinary circumstances radiation-induced promotes immune-mediated regression of non-irradiated lesions in a process termed the abscopal effect. Abscopal effects incompletely understood, involving balance...
Consolidation durvalumab improved overall survival (OS) in locally advanced non-small cell lung cancer (LA-NSCLC) treated with chemoradiotherapy (CRT) the PACIFIC trial; however, pneumonitis was increased durvalumab. We sought to examine real-world outcomes paradigm, especially factors associated pneumonitis, using a multi-institutional review.Patients LA-NSCLC CRT followed by from January 2017-February 2019 were identified at 2 institutions. characterized demographics, tumor factors,...
Focused ultrasound (FUS)-enabled liquid biopsy (sonobiopsy) is an emerging technique for the noninvasive and spatiotemporally controlled diagnosis of brain cancer by inducing blood-brain barrier (BBB) disruption to release tumor-specific biomarkers into blood circulation. The feasibility, safety, efficacy sonobiopsy were demonstrated in both small large animal models using magnetic resonance-guided FUS devices. However, high cost complex operation devices limit future broad application...
Abstract The role of acid-sensing ion channels (ASICs) in the ventrolateral medulla (VLM) remains uncertain. Here, we found that ASIC1a and ASIC2 are widely expressed rat medulla, expression level is higher at neonatal stage as compared to adult stage. two ASIC subunits co-localized medualla neurons. Furthermore, pH reduction triggered typical ASIC-type currents including VLM. These showed a 50 value 6.6 were blocked by amiloride. Based on their sensitivity psalmotoxin 1 (PcTx1) zinc,...
Purpose/Objectives: Multi-parametric advanced MR and FDG-PET imaging may be important biomarkers for prognosis as well distinguishing recurrent glioblastoma (GBM) from treatment-related changes. Methods/Materials: We retrospectively evaluated 30 patients treated with chemoradiation GBM underwent confirmation of tumor progression. MRI metrics were their association 6-month overall (OS) progression-free survival (PFS) based on pathological, radiographic, clinical criteria. Results: 17 males 13...
AMA Thomas H, Chen J, Shaheen et al. Safety of high-dose-rate brachytherapy in patients with prostate cancer and inflammatory bowel disease: A case series. Journal Contemporary Brachytherapy. 2024. doi:10.5114/jcb.2024.135645. APA Thomas, H., Chen, J., Shaheen, Sabbagh, A., Abdul-Baki, & Chau, O. (2024). https://doi.org/10.5114/jcb.2024.135645 Chicago Horatio, Jie Jane Haitham Ali Hasan Oi Wai Nauman Malik "Safety series". Harvard O., Malik, N., Ayoub, Hassanzadeh, C., Hsu, I., Mohamad, MLA...