A5053344144- Antibiotic Resistance in Bacteria
- Antifungal resistance and susceptibility
- Bacterial Identification and Susceptibility Testing
- Fungal Infections and Studies
- Antibiotic Use and Resistance
- Viral gastroenteritis research and epidemiology
- Antimicrobial Resistance in Staphylococcus
- Pneumonia and Respiratory Infections
- Salmonella and Campylobacter epidemiology
- Vibrio bacteria research studies
- Infective Endocarditis Diagnosis and Management
- Streptococcal Infections and Treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Hepatitis Viruses Studies and Epidemiology
- Pharmaceutical and Antibiotic Environmental Impacts
- Listeria monocytogenes in Food Safety
- Antibiotics Pharmacokinetics and Efficacy
- Orthopedic Infections and Treatments
- Urinary Tract Infections Management
- Plant Pathogens and Fungal Diseases
- Infectious Diseases and Tuberculosis
- Yersinia bacterium, plague, ectoparasites research
- Viral Infections and Outbreaks Research
- Food Safety and Hygiene
- Neutropenia and Cancer Infections
University Hospital Cologne
2022-2024
University Hospital Regensburg
2013-2024
University of Cologne
2022-2024
Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases
2024
University of Regensburg
2007-2023
Institute of Medical Microbiology and Hygiene
2012-2022
Instituto de Salud Carlos III
2020
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2020
Agencia de Salud Pública de Barcelona
2009-2014
University Hospital of Geneva
2010
Most COVID-19-associated mucormycosis (CAM) cases are reported from India and neighbouring countries. Anecdotally Europe have been presented.To estimate the disease burden describe clinical presentation of CAM in Germany.We identified through German mycology networks scientific societies, collected anonymised information via FungiScope®.We 13 six tertiary referral hospitals diagnosed between March 2020 June 2021. Twelve patients had severe or critical COVID-19, eleven were mechanically...
Abstract Between April and June 2020, i.e., during the first wave of pandemic coronavirus disease 2019 (COVID-19), 55 patients underwent long-term treatment in intensive care unit at University Hospital Regensburg. Most them were transferred from smaller hospitals, often due to need for an extracorporeal membrane oxygenation system. Autopsy was performed 8/17 COVID-19-proven after (mean: 33.6 days). revealed that typical pathological changes occurring early stages (e.g., thrombosis,...
Infection and inflammation are able to induce diet-independent Na+-accumulation without commensurate water retention in afflicted tissues, which favors the pro-inflammatory activation of mouse macrophages augments their antibacterial antiparasitic activity. While Na+-boosted host defense against protozoan parasite Leishmania major is mediated by increased expression leishmanicidal NOS2 (nitric oxide synthase 2, inducible), molecular mechanisms underpinning this enhanced with high Na+ (HS)...
Abstract Introduction In Germany, the growing incidence of invasive fungal infections (IFIs) is a significant health concern, particularly impacting individuals with compromised immune systems due to factors like increasing transplant recipients, an ageing population, and heightened use immunosuppressive medications. Diagnosing IFI remains challenging, integration biomarker assays into clinical practice difficult. Antifungal resistance, exemplified by pan-antifungal-resistant Candida auris...
Human cysticercosis caused by Taenia crassiceps tapeworm larvae involves the muscles and subcutis mostly in immunocompromised patients eye immunocompetent persons. We report a successfully treated cerebellar infection an woman. developed serologic tests, parasite was identified histologic examination 12s rDNA PCR sequencing.
Abstract We present four cases with Gram-positive bacteremia (pathogens: MRSA n = 1 , Enterococcus spp. 3) due to an intravascular source (left ventricular assist device: 2, transfemoral aortic valve implantation 1, prosthetic valve: 1) where no curative treatment was available. These patients received indefinite, chronic suppressive (palliative) therapy dalbavancin (500 mg weekly or 1000 biweekly regimens). Outcomes and clinical characteristics are described; effective in suppression of all...
Aim: Cold atmospheric plasma (CAP) has already proven efficient at disinfection of microorganisms including biofilms. The objective the present study is to assess efficacy CAP against dermatophytes Trichophyton rubrum and Microsporum canis in vitro. Materials & methods:T. M. were exposed for different treatment times time intervals Treatment with ciclopirox olamine or UVC radiation (0.120 J/cm2) served as controls. was generated by surface microdischarge technology. Fungal colony growth...
Community-acquired pneumonia due to Pseudomonas aeruginosa in previously healthy individuals is a rare disease that associated with high fatality. On 14 February 2010 49-year-old woman presented an emergency room signs and symptoms of pneumonia, 2 days after returning from spa holiday wellness hotel. Blood cultures respiratory specimens grew P. aeruginosa. Despite adequate antimicrobial therapy, the patient died septic multiorgan failure on day nine hospitalization. 26, water samples were...
Efficacy of antibiotic treatment implant-associated Staphylococcus aureus infections with moxifloxacin, flucloxacillin, rifampin, and combination therapy: an animal study Felix Greimel,1 Christine Scheuerer,1 Andre Gessner,2 Michaela Simon,2 Thomas Kalteis,1 Joachim Grifka,1 Achim Benditz,1 Hans-Robert Springorum,1 Jens Schaumburger1 1Department Orthopedics, University Medical Center Regensburg, Asklepios Klinikum Bad Abbach, 2Institute Clinical Microbiology Hygiene, Bavaria, Germany...
L. CASANOVAS, M. DE SIMÓN, M.D. FERRER, J. ARQUÉS AND G. MONZÓN. 1995. The faecal bacterial flora of pigeons, which may be the source infectious diseases in man, was studied city Barcelona. Four hundred cloacal specimens were examined for Campylobacter jejuni, Camp. coli, Salmonella spp., Yersinia spp. and Listeria over a 12 month period. jejuni most frequently isolated micro‐organism, found 105 pigeons (26.2%), with greater incidence districts high density without seasonal variation. from...
Blood cultures from a heroin user who died in June 2012, few hours after hospital admission, due to acute septic disease, revealed the presence of Bacillus anthracis. This report describes extended diagnosis by MALDI-TOF and real-time PCR rapid confirmation anthrax infection through reference laboratories. Physicians diagnostic laboratories were informed alerted efficiently reporting channels German public health institutions, which is essential for prevention further cases.
Abstract The European Confederation of Medical Mycology (ECMM), formed due to the surge in invasive fungal infections (IFI), initiated Excellence Centers program 2016 guide stakeholders leading medical mycology sites. This report focuses on Cologne ECMM Center, recognized with Diamond status for active global involvement 2017. center offers free consultation via email and phone, responding within 24 h life-threatening IFI, collecting data origin, pathogens, infection details, more. Over two...
Fungal implant-associated bone infections are rare but difficult to treat and often associated with a poor outcome for patients. Candida species account approximately 90% of all fungal infections. In vivo biofilm models play major role study development potential new treatment options; however, there only very few in fungi-associated biofilms. Furthermore, mammalian infection replaced more due ethical restrictions other alternative basic research. Recently, we developed an insect model...