A5100606510- Corneal surgery and disorders
- Ophthalmology and Visual Impairment Studies
- Glaucoma and retinal disorders
- Liver Disease Diagnosis and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Ocular Surface and Contact Lens
- Inflammasome and immune disorders
- Inflammatory Myopathies and Dermatomyositis
- Pancreatitis Pathology and Treatment
- Gout, Hyperuricemia, Uric Acid
- Alcohol Consumption and Health Effects
- Plant and Fungal Interactions Research
- Selenium in Biological Systems
- Birth, Development, and Health
- Immunodeficiency and Autoimmune Disorders
- Intraocular Surgery and Lenses
- Pregnancy and preeclampsia studies
- Plant Disease Resistance and Genetics
- Gallbladder and Bile Duct Disorders
- Autophagy in Disease and Therapy
- Thyroid Cancer Diagnosis and Treatment
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- MRI in cancer diagnosis
- T-cell and B-cell Immunology
- Pancreatic and Hepatic Oncology Research
Tianjin Medical University
2020-2025
Nankai University
2021-2025
Tianjin Medical University Eye Hospital
2020-2025
Zhongshan Hospital
2024
Fudan University
2019-2024
Shanghai Ninth People's Hospital
2023-2024
Shanghai Jiao Tong University
2019-2024
First Affiliated Hospital of Zhengzhou University
2021-2024
National Clinical Research
2024
Shanghai Stomatological Hospital
2024
Abstract Circulating neutrophil extracellular traps (NETs) resistant to t‐PA have not been studied completely although NETs in thrombi may contribute tissue plasminogen activator (t‐PA) resistance. This research intended elucidate whether circulating are associated with resistance and the underlying mechanism. The levels of were detected neutrophils, ischemic brain acute stroke (AIS) patients, transient middle cerebral artery occlusion (tMCAO) models. NET formation blood, thrombi, mice...
Objective The objective of this study is to investigate the risk and prognostic factors for radioactive iodine (RAI)-refractory (RAIR) differentiated thyroid cancer (DTC) with distant metastasis. Methods A total 128 patients metastasis-DTC who underwent iodine-131 radiotherapy were included in cohort study. After exclusion, 75 DTC resistant radioiodine therapy 53 whom treatment was successful finally included. Clinical data as well BRAF V600E telomerase reverse transcriptase (TERT) promoter...
With the advancement of technology and popularity new media, short videos have become increasingly prominent in field cultural communication. Bilibili, a platform known for encouraging high-quality video production providing highly interactive environment, is favored by young people. The “YChina” has gained significant influence on this due to its solid fan base strong communication capabilities. Therefore, study selects 60 released Bilibili from January 9, 2023, April 3, 2024, as research...
In the current environment of actively advocating telling Chinese stories in China, with rise short video platforms "we media", many foreign bloggers take this opportunity to share stories, show their eyes China from perspective "other", and arouse attention discussion majority netizens through comparison cultural differences, becoming ambassadors cross-cultural communication. This study selected "I am Jerry Kowal", a well-known blogger on bilibili, very representative platform as research...
Purpose: The purpose of this study was to quantify the corneal power changes after wearing orthokeratology lenses different back optic zone diameters (BOZDs) and propose a novel 4-parameter model capable revealing associations between each parameter axial length growth (ALG). Methods: A prospective self-controlled conducted June 2022 December 2023. One eye in subject (N = 33) randomly assigned wear lens with BOZD either 5 mm (5 oz) or 6 (6 oz). Axial lengths were measured at 12 months ALG...
Straw application (SP) is a promising strategy for the improvement of soil fertility, but biological effects and mechanisms its on microorganisms remain unclear. The investigation into tea plantations (CK/S) in southern Henan, China, without/with straw amendment was carried out to assess SP bacterial communities using high-throughput sequencing. induced community restructuring dominant phyla, e.g., Acidobacteriota, Pseudomonadota, Chloroflexota, with significantly increasing Nitrospirota,...
Abstract Background To assess the corneal stress-strain index (SSI), which is a marker for material stiffness and biomechanical parameters, in myopic eyes. Methods A total of 1054 patients were included this study. Corneal visualisation Scheimpflug technology was used to measure SSI. biomechanics assessed using first second applanation times (A1-and A2-times); maximum deflection amplitude (DefAmax); area (HCDefArea); highest concavity peak distance (HC-PD), time (HC-time), (HC-DefA);...
Serum uric acid (SUA) is associated with many cardiovascular risk factors, such as metabolic syndrome (MetS) and subclinical atherosclerosis. However, the relationship of SUA carotid atherosclerosis remains controversial. We aimed to investigate whether elevated levels are a high MetS in patients type 2 diabetes mellitus (T2DM). This cross-sectional study was performed sample 1,947 hospitalized T2DM. Carotid intima-media thickness artery plaques were measured via Doppler ultrasound. Uric...
Chemiluminescence (CL) imaging has high sensitivity with significantly increased signal-to-background ratio due to no interferences of light source and autofluorescence. However, it is still a great challenge design synthesize highly sensitive CL probe that acquires intensive long-lasting emission. Here, we demonstrate mimic-enzyme catalytic polymer dots (polystyrene (PS)–hemin dots) consisting hemin, polystyrene, amphiphilic polymer. emission catalyzed by PS–hemin tremendously, 6000-fold...
This study aimed to investigate the association of serum bone turnover markers (BTMs) with metabolic syndrome components and carotid atherosclerosis in patients type 2 diabetes mellitus (T2DM). We performed a cross-sectional based T2DM populations. Serum BTMs including N-terminal osteocalcin (N-MID), β-cross-linked C-telopeptide I collagen (β-CTX), procollagen propeptide (PINP) were measured by immunoassay method. Carotid artery intima-media thickness plaque (CAP) B-mode ultrasound. The...
Abstract Selenium deficiency is thought to be associated with the occurrence of gestational complications. However, underlying mechanism selenium impairs placental function remains unclear. In this study, female mice were separately supplemented a Se-deficient (0.02 mg/kg Se) or control diet (0.2 for 12 weeks before mating and throughout gestation. Maternal liver placentas collected at embryonic day 15.5 analyzed Se content. Oxidative stress status, proliferation capability, autophagy,...
The aim of this study was to construct crosslinked polylysine-hyaluronic acid microspheres (pl-HAM) ladened with gingival mesenchymal stem cells (GMSCs) and explore its biologic behavior in soft tissue regeneration.
Terahertz technology has shown broad prospects for measuring corneal water content, which is an important parameter of ocular health. Based on terahertz time-domain spectroscopy, a new indicator named characteristic ratio (CR) the sum low (0.2-0.7 THz) and high (0.7-1.0 frequency spectral intensities, characterizing hydration introduced in this work. CR calculated from real-time reflection spectra after error elimination ex vivo human stroma samples collected during dehydration under natural...
Identifying priority zones for river restoration is important biodiversity conservation and catchment management. However, limited data due to the difficulty of field collection has led research better understand ecological status within a develop targeted planning strategy restoration. To address this need, coupling hydrological machine learning models were constructed identify based on dataset aquatic organisms (i.e., algae, macroinvertebrates, fish) physicochemical indicators that...
Purpose: To investigate environmental factors associated with corneal morphologic changes. Methods: A cross-sectional study was conducted, which enrolled adults of the Han ethnicity aged 18 to 44 years from 20 cities. The cornea-related morphology measured using an ocular anterior segment analysis system. geographic indexes each city and meteorological daily city-level data past 40 (1980–2019) were obtained. Correlation analyses at level multilevel model eye performed. Results: In total,...
Abstract Objectives To validate an appropriate evaluation method of liver fibrosis assessment based on the unique pathological features biliary atresia (BA) that could well predict its prognosis. Methods A total 68 patients with BA who underwent Kasai procedure (KP) and intraoperative biopsy, followed up from January 2019 to December 2021, were recruited in a retrospective analysis. Ishak, Metavir, BA-specific staging systems relation outcomes analyzed using logistic regression, COX...
Aging is a major risk factor for various eye diseases, such as cataract, glaucoma, and age-related macular degeneration. Age-related changes are observed in almost all structures of the human eye. Considerable individual variations exist within group similarly aged individuals, indicating need more informative biomarkers assessing aging eyes. The morphology ocular anterior segment has been reported to vary across age groups, focusing on only few corneal parameters, keratometry thickness...
The Rho kinase inhibitor fasudil exerts neuroprotective effects. We previously showed that can regulate M1/M2 microglia polarization and inhibit neuroinflammation. Here, the therapeutic effect of on cerebral ischemia‑reperfusion (I/R) injury was investigated using middle artery occlusion reperfusion (MCAO/R) model in Sprague‑Dawley rats. phenotype neurotrophic factors I/R brain its potential molecular mechanism also explored. It found ameliorated neurological deficits, neuronal apoptosis,...