Laurent Brisard
A5043609414- Airway Management and Intubation Techniques
- Respiratory Support and Mechanisms
- Clinical Nutrition and Gastroenterology
- Aortic aneurysm repair treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Nutrition and Health in Aging
- Intensive Care Unit Cognitive Disorders
- Aortic Disease and Treatment Approaches
- Cardiac Arrest and Resuscitation
- Hemodynamic Monitoring and Therapy
- Pneumonia and Respiratory Infections
- Tracheal and airway disorders
- Infectious Aortic and Vascular Conditions
- Radiation Dose and Imaging
- Simulation-Based Education in Healthcare
- Advanced X-ray and CT Imaging
- Anesthesia and Sedative Agents
- Anesthesia and Pain Management
- Interpreting and Communication in Healthcare
- Non-Invasive Vital Sign Monitoring
- Nosocomial Infections in ICU
- Traumatic Brain Injury and Neurovascular Disturbances
- Abdominal vascular conditions and treatments
- Pediatric Pain Management Techniques
- Body Composition Measurement Techniques
Centre Hospitalier Universitaire de Nantes
2012-2024
Hôpital Laennec
2013-2023
Nantes Université
2013-2022
Hôpital Nord
2014-2021
Hôpital Mère-Enfant
2012-2015
Institut du Thorax
2014
Institut Génétique Nantes Atlantique
2014
Centre Hospitalier Guillaume Régnier
2013
Centre d'Investigation Clinique de Nantes
2010
Ceftriaxone is widely used to treat community-acquired CNS bacterial infections. French guidelines for meningitis in adults promote 75–100 mg/kg/day ceftriaxone without an upper limit dosage, yet little known about the pharmacology and tolerability of such regimens. A multicentre prospective cohort study was conducted adult patients assess adverse drug reactions (ADRs) high-dose (i.e. daily dosage ≥4 g or ≥75 mg/kg) infections analyse their related factors. Drug causality systematically...
Nutritional support is crucial to the management of patients receiving invasive mechanical ventilation (IMV) and most commonly prescribed treatment in intensive care units (ICUs). International guidelines consistently indicate that enteral nutrition (EN) should be preferred over parenteral (PN) whenever possible started as early possible. However, no adequately designed study has evaluated whether a specific nutritional modality associated with decreased mortality. The primary goal this...
In Brief BACKGROUND: The Manujet™ and the ENK Oxygen Flow Modulator™ (ENK) deliver oxygen during transtracheal oxygenation. We sought to describe ventilation characteristics of these 2 devices. METHODS: study was conducted in an artificial lung model consisting a 15-cm ringed tube, simulating trachea, connected via flow analyzer lung. A 15-gauge wire reinforced catheter used for Manujet were studied 3 minutes at respiratory rates 0, 4, 12 breaths/min, with without lung, totally partially...
Introduction International guidelines include early nutritional support (≤48 hour after admission), 20–25 kcal/kg/day, and 1.2–2 g/kg/day protein at the acute phase of critical illness. Recent data challenge appropriateness providing standard amounts calories during Restricting calorie intakes seemed beneficial, suggesting a role for metabolic pathways such as autophagy, potential key mechanism in safeguarding cellular integrity, notably muscle, However, optimal supply severe illness remains...
Despite recent improvements, spinal cord ischemia remains the most feared and dramatic complication following extensive aortic repair. Although endovascular procedures are associated with a lower risk compared open procedures, this is still significant must be considered. A combined medical surgical approach may help to optimize tolerance of ischemia. The aim review describe underlying mechanism involved in injury during repair, different techniques used improve ischemia-including...
Purpose: Spinal cord injury (SCI) is a devastating complication of thoracoabdominal aortic (TAA) repair. The use prophylactic cerebrospinal fluid drainage (CSFD) as part protective protocol during endovascular repair controversial. This article reports the results CSFD prevention implemented in 2016. Methods: Retrospective review spinal outcomes (SCI rate and CSFD-related complications) patients treated endovascularly for TAA disease at single institution from 2016 (implementation an...
A widely used physiological simulator is generally accepted to give valid predictions of oxygenation status during disturbances in breathing associated with anesthesia. We compared predicted measures measurements available the literature, or derived from other models.Five studies were selected literature which explored arterial oxygenation, without preoxygenation, clinical situations through mathematical modeling as well evolution fraction expired oxygen (Feo2) preoxygenation maneuvers....
Extracorporeal life support may be used in patients with refractory cardiogenic shock. The femoral venoarterial route can for implanting cannulae who are hemodynamically unstable. Here we describe the use of an ultrasound-guided transversus abdominis plane block supplemented component genitofemoral nerve as anesthesia technique peripheral cannulation vessels a patient severe acute heart failure after myocardial infarction ST-segment elevation. procedure was performed using 40 mL 50:50...
Early nutrition management in patients receiving extracorporeal membrane oxygenation (ECMO) remains controversial. Despite its potentially beneficial effect, enteral (EN) could be associated with gastrointestinal (GI) complications. Total daily energy requirements remain difficult to achieve ECMO support. Analysis of practices improve this particular population.A monocentric retrospective study requiring a cardiac surgery intensive care unit (ICU) between 2010 and 2014 follow-up ≥6 days....