Michaël Darmon
- Sepsis Diagnosis and Treatment
- Acute Kidney Injury Research
- Respiratory Support and Mechanisms
- Neutropenia and Cancer Infections
- Nosocomial Infections in ICU
- Intensive Care Unit Cognitive Disorders
- Cardiac Arrest and Resuscitation
- Dialysis and Renal Disease Management
- Hemodynamic Monitoring and Therapy
- Pneumonia and Respiratory Infections
- Renal function and acid-base balance
- Methemoglobinemia and Tumor Lysis Syndrome
- Palliative Care and End-of-Life Issues
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- COVID-19 Clinical Research Studies
- Family and Patient Care in Intensive Care Units
- Chronic Kidney Disease and Diabetes
- Neonatal Health and Biochemistry
- Muscle and Compartmental Disorders
- Complement system in diseases
- Long-Term Effects of COVID-19
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac, Anesthesia and Surgical Outcomes
- Blood disorders and treatments
- Pneumocystis jirovecii pneumonia detection and treatment
Sorbonne Paris Cité
2018-2025
Hôpital Saint-Louis
2015-2025
Inserm
1995-2025
European Society of Intensive Care Medicine
2025
Clinical Trial Investigators
2025
Assistance Publique – Hôpitaux de Paris
2012-2024
Université Paris Cité
2011-2024
Centre de Recherche Épidémiologie et Statistique
2018-2024
Hôpital Fernand-Widal
2021-2024
Délégation Paris 7
2009-2023
Intensive care unit (ICU) admission of a relative is stressful event that may cause symptoms post-traumatic stress disorder (PTSD).Factors associated with these need to be identified.For patients admitted 21 ICUs between March and November 2003, we studied the family member main potential decision-making role.Ninety days after ICU discharge or death, members completed Impact Event Scale (which evaluates severity reactions), Hospital Anxiety Depression Scale, 36-item Short-Form General Health...
There is a need for close communication with relatives of patients dying in the intensive care unit (ICU). We evaluated format that included proactive end-of-life conference and brochure to see whether it could lessen effects bereavement.
Purpose Patients with hematologic malignancies are increasingly admitted to the intensive care unit (ICU) when life-threatening events occur. We sought report outcomes and prognostic factors in these patients. Methods Ours was a prospective, multicenter cohort study of critically ill patients malignancies. Health-related quality life (HRQOL) disease status were collected after 3 6 months. Results Of 1,011 patients, 38.2% had newly diagnosed malignancies, 23.1% remission, 24.9% received...
for the Groupe de Recherche en Réanimation Respiratoire du patient d'Onco-Hématologie (GRRR-OH) IMPORTANCE Noninvasive ventilation has been recommended to decrease mortality among immunocompromised patients with hypoxemic acute respiratory failure.However, its effectiveness this indication remains unclear.OBJECTIVE To determine whether early noninvasive improved survival in nonhypercapnic failure.
Abstract Background The COVID-19 pandemic has resulted in an unprecedented healthcare crisis with a high prevalence of psychological distress providers. We sought to document the burnout syndrome amongst intensivists facing outbreak. Methods Cross-sectional survey among part European Society Intensive Care Medicine. Symptoms severe burnout, anxiety and depression were collected. Factors independently associated assessed using Cox model. Results Response rate was 20% (1001 completed...
Cancer patients requiring mechanical ventilation are widely viewed as poor candidates for intensive care unit (ICU) admission. We designed a prospective study evaluating new admission policy titled The ICU Trial.Prospective study.Intensive unit.One hundred eighty-eight and having at least one other organ failure.Over 3-yr period, all with hematologic malignancies or solid tumors proposed underwent triage procedure. Bedridden in whom palliative was the only cancer treatment option were not...
A few decades have passed since intensive care unit (ICU) beds been available for critically ill patients with cancer. Although the initial reports showed dismal prognosis, recent data suggest that an increased number of solid and hematological malignancies benefit from support, dramatically decreased mortality rates. Advances in management underlying support organ dysfunctions led to survival gains life-threatening complications malignancy itself, as well infectious toxic adverse effects...
<h3>Importance</h3> High-flow nasal oxygen therapy is increasingly used for acute hypoxemic respiratory failure (AHRF). <h3>Objective</h3> To determine whether high-flow decreases mortality among immunocompromised patients with AHRF compared standard therapy. <h3>Design, Setting, and Participants</h3> The HIGH randomized clinical trial enrolled 776 adult (Pao<sub>2</sub><60 mm Hg or Spo<sub>2</sub><90% on room air, tachypnea >30/min labored breathing distress, need ≥6 L/min) at 32...
To determine whether the survival gains achieved in critically ill cancer patients recent years exist subset with neutropenia and severe sepsis or septic shock.Retrospective 11-yr study (1998-2008).Medical intensive care unit a teaching hospital.Four hundred twenty-eight cancer, neutropenia, shock. The primary outcome was hospital mortality.The main underlying diseases were acute leukemia (35.7%), lymphoma (31.7%), solid tumors (16.5%). Two thirty-seven (55.5%) had microbiologically...
Rationale: Frontline healthcare providers (HCPs) during the coronavirus disease (COVID-19) pandemic are at high risk of mental morbidity.Objectives: To assess prevalence symptoms anxiety, depression, and peritraumatic dissociation in HCPs.Methods: This was a cross-sectional study 21 ICUs France between April 20, 2020, May 21, 2020. The Hospital Anxiety Depression Scale Peritraumatic Dissociative Experience Questionnaire were used. Factors independently associated with reported health...
Multi-organ dysfunction in critical illness is common and frequently involves the lungs kidneys, often requiring organ support such as invasive mechanical ventilation (IMV), renal replacement therapy (RRT) and/or extracorporeal membrane oxygenation (ECMO).
Acute respiratory failure (ARF) in patients with cancer is frequently a fatal event. To identify factors associated survival of admitted to an intensive care unit (ICU) for ARF, we conducted prospective 5-year observational study medical ICU teaching hospital Paris, France. The were 203 ARF mainly due infectious pneumonia (58%), but also noninfectious (9%), congestive heart (12%), and no identifiable cause (21%). We measured clinical characteristics mortality rates.ICU was 44.8% 47.8%....