Michaël Darmon

ORCID: 0000-0003-4198-8038
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About
Contact & Profiles
Research Areas
  • Sepsis Diagnosis and Treatment
  • Acute Kidney Injury Research
  • Respiratory Support and Mechanisms
  • Neutropenia and Cancer Infections
  • Nosocomial Infections in ICU
  • Intensive Care Unit Cognitive Disorders
  • Cardiac Arrest and Resuscitation
  • Dialysis and Renal Disease Management
  • Hemodynamic Monitoring and Therapy
  • Pneumonia and Respiratory Infections
  • Renal function and acid-base balance
  • Methemoglobinemia and Tumor Lysis Syndrome
  • Palliative Care and End-of-Life Issues
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • COVID-19 Clinical Research Studies
  • Family and Patient Care in Intensive Care Units
  • Chronic Kidney Disease and Diabetes
  • Neonatal Health and Biochemistry
  • Muscle and Compartmental Disorders
  • Complement system in diseases
  • Long-Term Effects of COVID-19
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Cardiac, Anesthesia and Surgical Outcomes
  • Blood disorders and treatments
  • Pneumocystis jirovecii pneumonia detection and treatment

Sorbonne Paris Cité
2018-2025

Hôpital Saint-Louis
2015-2025

Inserm
1995-2025

European Society of Intensive Care Medicine
2025

Clinical Trial Investigators
2025

Assistance Publique – Hôpitaux de Paris
2012-2024

Université Paris Cité
2011-2024

Centre de Recherche Épidémiologie et Statistique
2018-2024

Hôpital Fernand-Widal
2021-2024

Délégation Paris 7
2009-2023

Intensive care unit (ICU) admission of a relative is stressful event that may cause symptoms post-traumatic stress disorder (PTSD).Factors associated with these need to be identified.For patients admitted 21 ICUs between March and November 2003, we studied the family member main potential decision-making role.Ninety days after ICU discharge or death, members completed Impact Event Scale (which evaluates severity reactions), Hospital Anxiety Depression Scale, 36-item Short-Form General Health...

10.1164/rccm.200409-1295oc article EN American Journal of Respiratory and Critical Care Medicine 2005-01-22

Purpose Patients with hematologic malignancies are increasingly admitted to the intensive care unit (ICU) when life-threatening events occur. We sought report outcomes and prognostic factors in these patients. Methods Ours was a prospective, multicenter cohort study of critically ill patients malignancies. Health-related quality life (HRQOL) disease status were collected after 3 6 months. Results Of 1,011 patients, 38.2% had newly diagnosed malignancies, 23.1% remission, 24.9% received...

10.1200/jco.2012.47.2365 article EN Journal of Clinical Oncology 2013-06-11
Jean Reignier Julie Helms Laurent Brisard Jean-Baptiste Lascarrou Ali Ait Hssain and 95 more Nadia Anguel Laurent Argaud Karim Asehnoune Pierre Asfar Frédéric Bellec Vlad Botoc Anne Bretagnol Hoang-Nam Bui Emmanuel Canet Daniel Silva Michaël Darmon Vincent Das Jérôme Devaquet Michel Djibré Frédérique Ganster Maïté Garrouste-Orgeas Stéphane Gaudry Olivier Gontier Claude Guérin Bertrand Guidet Christophe Guitton Jean-Étienne Herbrecht Jean-Claude Lachérade Philippe Letocart Frédéric Martino Virginie Maxime Emmanuelle Mercier Jean‐Paul Mira Saad Nseir Gaël Piton Jean‐Pierre Quenot Jack Richecoeur Jean‐Philippe Rigaud R. Robert Nathalie Rolin Carole Schwebel Michel Sirodot François Tinturier Didier Thévenin Bruno Giraudeau Amélie Le Gouge Hervé Dupont Marc Pierrot François Beloncle Danièle Combaux Romain Mercier Hadrien Winiszewski Gilles Capellier Gilles Hilbert Didier Gruson Pierre Kalfon Bertrand Souweine Elizabeth Coupez Jean‐Damien Ricard Jonathan Messika François Bougerol Pierre-Louis Declercq Auguste Dargent Audrey Large Djillali Annane Bernard Clair Agnès Bonadona Rébecca Hamidfar Christian Richard M. Henry-Lagarrigue Ahiem Yehia Yehia Johanna Temime Stéphanie Barrailler Raphaël Favory Erika Parmentier-Decrucq M. Jourdain Loredana Baboi Marie Simon Thomas Baudry Mehran Monchi Jérôme Roustan Patrick Bardou Alice Cottereau Philippe Guiot N. Brulé Mickaël Landais Antoine Roquilly Thierry Boulain Dalila Benzekri Benoît Champigneulle Jalel Tahiri Gabriel Preda Benoît Misset Virginie Lemiale Lara Zafrani Muriel Fartoukh Guillaume Thiéry Delphine Chatellier Rémi Coudroy Renaud Chouquer

10.1016/s0140-6736(17)32146-3 article EN The Lancet 2017-11-09

for the Groupe de Recherche en Réanimation Respiratoire du patient d'Onco-Hématologie (GRRR-OH) IMPORTANCE Noninvasive ventilation has been recommended to decrease mortality among immunocompromised patients with hypoxemic acute respiratory failure.However, its effectiveness this indication remains unclear.OBJECTIVE To determine whether early noninvasive improved survival in nonhypercapnic failure.

10.1001/jama.2015.12402 article EN JAMA 2015-10-07

Abstract Background The COVID-19 pandemic has resulted in an unprecedented healthcare crisis with a high prevalence of psychological distress providers. We sought to document the burnout syndrome amongst intensivists facing outbreak. Methods Cross-sectional survey among part European Society Intensive Care Medicine. Symptoms severe burnout, anxiety and depression were collected. Factors independently associated assessed using Cox model. Results Response rate was 20% (1001 completed...

10.1186/s13613-020-00722-3 article EN cc-by Annals of Intensive Care 2020-08-08

Cancer patients requiring mechanical ventilation are widely viewed as poor candidates for intensive care unit (ICU) admission. We designed a prospective study evaluating new admission policy titled The ICU Trial.Prospective study.Intensive unit.One hundred eighty-eight and having at least one other organ failure.Over 3-yr period, all with hematologic malignancies or solid tumors proposed underwent triage procedure. Bedridden in whom palliative was the only cancer treatment option were not...

10.1097/01.ccm.0000256846.27192.7a article EN Critical Care Medicine 2007-01-19

10.1016/s0140-6736(18)31080-8 article EN The Lancet 2018-06-14

A few decades have passed since intensive care unit (ICU) beds been available for critically ill patients with cancer. Although the initial reports showed dismal prognosis, recent data suggest that an increased number of solid and hematological malignancies benefit from support, dramatically decreased mortality rates. Advances in management underlying support organ dysfunctions led to survival gains life-threatening complications malignancy itself, as well infectious toxic adverse effects...

10.1186/2110-5820-1-5 article EN cc-by Annals of Intensive Care 2011-03-23

<h3>Importance</h3> High-flow nasal oxygen therapy is increasingly used for acute hypoxemic respiratory failure (AHRF). <h3>Objective</h3> To determine whether high-flow decreases mortality among immunocompromised patients with AHRF compared standard therapy. <h3>Design, Setting, and Participants</h3> The HIGH randomized clinical trial enrolled 776 adult (Pao<sub>2</sub>&lt;60 mm Hg or Spo<sub>2</sub>&lt;90% on room air, tachypnea &gt;30/min labored breathing distress, need ≥6 L/min) at 32...

10.1001/jama.2018.14282 article EN JAMA 2018-10-25

To determine whether the survival gains achieved in critically ill cancer patients recent years exist subset with neutropenia and severe sepsis or septic shock.Retrospective 11-yr study (1998-2008).Medical intensive care unit a teaching hospital.Four hundred twenty-eight cancer, neutropenia, shock. The primary outcome was hospital mortality.The main underlying diseases were acute leukemia (35.7%), lymphoma (31.7%), solid tumors (16.5%). Two thirty-seven (55.5%) had microbiologically...

10.1097/ccm.0b013e31822b50c2 article EN Critical Care Medicine 2011-10-04

Rationale: Frontline healthcare providers (HCPs) during the coronavirus disease (COVID-19) pandemic are at high risk of mental morbidity.Objectives: To assess prevalence symptoms anxiety, depression, and peritraumatic dissociation in HCPs.Methods: This was a cross-sectional study 21 ICUs France between April 20, 2020, May 21, 2020. The Hospital Anxiety Depression Scale Peritraumatic Dissociative Experience Questionnaire were used. Factors independently associated with reported health...

10.1164/rccm.202006-2568oc article EN cc-by-nc-nd American Journal of Respiratory and Critical Care Medicine 2020-08-31

Multi-organ dysfunction in critical illness is common and frequently involves the lungs kidneys, often requiring organ support such as invasive mechanical ventilation (IMV), renal replacement therapy (RRT) and/or extracorporeal membrane oxygenation (ECMO).

10.1007/s00134-019-05869-7 article EN cc-by-nc Intensive Care Medicine 2019-12-09
Jean Reignier Gaëtan Plantefève Jean‐Paul Mira Laurent Argaud Pierre Asfar and 95 more Nadia Aïssaoui Julio Badié Nicolae-Vlad Botoc Laurent Brisard Hoang-Nam Bui Delphine Chatellier Louis Chauvelot Alain Combes Christophe Cracco Michaël Darmon Vincent Das Matthieu Débarre Agathe Delbove Jérôme Devaquet Louis‐Marie Dumont Olivier Gontier Samuel Groyer Laurent Guérin Bertrand Guidet Yannick Hourmant Samir Jaber Fabien Lambiotte Christophe Leroy Philippe Letocart Benjamin Madeux Julien Maizel Olivier Martinet Frédéric Martino Virginie Maxime Emmanuelle Mercier Mai-Anh Nay Saad Nseir Johanna Oziel Walter Picard Gaël Piton Jean‐Pierre Quenot Florian Reizine Anne Renault Jack Richecoeur Jean‐Philippe Rigaud Francis Schneider Daniel Silva Michel Sirodot Bertrand Souweine Fabienne Tamion Nicolas Terzi Didier Thévenin Guillaume Thiéry Nathalie Thieulot-Rolin Jean‐François Timsit François Tinturier Patrice Tirot Thierry Vanderlinden Isabelle Vinatier Christophe Vinsonneau Sébastian Voicu Jean-Baptiste Lascarrou Amélie Le Gouge Damien Contou Olivier Pajot Paul Jaubert Nathalie Marin Marie Simon Martin Cour Satar Mortaza Vincent Souday Marie Lemerle Sylvain Malfroy Fernando Berdaguer Ferrari Bertrand Rozec Didier Gruson Charline Sazio Suzanne Champion Florence Boissier Anne Veinstein Loredana Baboi Jean‐Christophe Richard Hodane Yonis Loïc Le Guennec Lucie Lefèvre Juliette Chommeloux Guillaume Hékimian Virginie Lemiale Éric Mariotte Sandrine Valade Joanna Tirolien Yannick Fédun Charles Cerf Guillaume Tachon Jérôme Roustan Sylvie Vimeux Michel Bonnivard Nadia Anguel David Osman Karim Asehnoune

10.1016/s2213-2600(23)00092-9 article EN publisher-specific-oa The Lancet Respiratory Medicine 2023-03-21

Acute respiratory failure (ARF) in patients with cancer is frequently a fatal event. To identify factors associated survival of admitted to an intensive care unit (ICU) for ARF, we conducted prospective 5-year observational study medical ICU teaching hospital Paris, France. The were 203 ARF mainly due infectious pneumonia (58%), but also noninfectious (9%), congestive heart (12%), and no identifiable cause (21%). We measured clinical characteristics mortality rates.ICU was 44.8% 47.8%....

10.1097/01.md.0000145370.63676.fb article EN Medicine 2004-11-01
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